Conditions listing Fibromyalgia as a symptom may also be potential underlying causes of Fibromyalgia. Our database lists the following as having Fibromyalgia as a symptom of that condition:
Causes: Fibromyalgia:
Although the cause of fibromyalgia is unknown, researchers
have several theories about what triggers the disease. Some scientists
believe that the syndrome may result from an injury or trauma. This
injury may affect the central nervous system. Fibromyalgia may be
associated with changes in muscle metabolism, such as decreased blood
flow, causing fatigue and decreased strength. Others believe the
syndrome may be triggered by an infectious agent such as a virus in
susceptible people, but no such agent has been identified.
(Source: excerpt from Fibromyalgia Research Challenges and Opportunities: NIAMS)
Article excerpts about the
causes of Fibromyalgia:
Although the cause of fibromyalgia is unknown, researchers have several
theories about causes or triggers of the disease. Some scientists believe
that the syndrome may be caused by an injury or traumThis injury may
affect the central nervous system. Fibromyalgia may be associated with
changes in muscle metabolism, such as decreased blood flow, causing
fatigue and decreased strength. Others believe the syndrome may be
triggered by an infectious agent such as a virus in susceptible people,
but no such agent has been identified. (Source: excerpt from Fibromyalgia: NWHIC)
The following conditions are listed as possible triggers for Fibromyalgia:
The following medical news items are relevant to causes of Fibromyalgia:
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Fibromyalgia may be found in:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Fibromyalgia.
The cause of FMS is unknown, but many theories exist regarding its pathophysiology. Although the pain is located primarily in muscle areas, no distinct abnormalities have been documented on microscopic evaluation of biopsies of tender points when compared to normal muscle. Other theories suggest decreased blood flow to muscle tissue (due to poor muscle aerobic conditioning versus other physiologic abnormalities); decreased blood flow in the thalamus and caudate nucleus, leading to a lowering of the pain threshold; endocrine dysfunction such as abnormal pituitary-adrenal axis responses; and abnormal levels of the neurotransmitter serotonin in brain centers, which affect pain and sleep. Abnormal functioning of other pain-processing pathways may also be involved. Considerable overlap of symptoms with other pain syndromes, such as chronic fatigue syndrome, raises the question of an association with an infection such as with parvovirus B19. Human immunodeficiency virus (HIV) infection and Lyme disease have also been associated with FMS.
It’s possible that the development of FMS is multifactorial and is influenced by stress (physical and mental), physical conditioning, and quality of sleep as well as by neuroendocrine, psychiatric and, possibly, hormonal factors (because of the female predominance).
Source: Handbook of Diseases, 2003
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