Clinical Trials for Fibrosis

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Fibrosis is grouped into the following categories:-

• View by trial name
• View by drugs used in Fibrosis clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Fibrosis:

• The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Interferon gamma-1b ("Actimmune")
• An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF - This study is no longer recruiting patients (Current: 23 Nov 2006) - Interferon gamma-1b
• Pirfenidone for the Treatment of Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis (PF/IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Pirfenidone
• Gleevec Idiopathic Pulmonary Fibrosis (IPF) Study - This study has been completed (Current: 23 Nov 2006) - Imatinib Mesylate (Gleevec)
• Behavioral & Nutritional Treatment to Help CF Preschoolers Grow - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Study Evaluating the Safety and Efficacy of Etanercept in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Etanercept
• Trial of Pentoxifylline in Patients With Functional Disability Caused by Radiation-Induced Advanced Regional Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study is currently recruiting patients (Current: 23 Nov 2006) - GC1008, Human Anti-Transforming Growth Factor-b 1, 2, 3 mAb
• Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lung Disease Associated With Rheumatoid Arthritis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Specimen Collection for Individuals With Lung Disease Associated With Rheumatoid Arthritis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Safety and Efficacy Study of Aztreonam Lysinate for Inhalation (AI) in Cystic Fibrosis Patients With P. Aeruginosa - This study is no longer recruiting patients (Current: 23 Nov 2006) - aztreonam lysinate for inhalation (AI)
• International Safety and Efficacy Study of Aztreonam Lysinate for Inhalation (AI) in Cystic Fibrosis Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - aztreonam lysinate for inhalation (AI)
• Specimen Procurement From People With Hereditary Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Safety and Tolerability Study of FG-3019 in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006) - FG-3019
• Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis) - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
• Efficacy of Prazosin Versus Placebo Associated With Peg-Interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Peg-interferon alpha 2b (drug),Ribavirin (drug),Prazosin (drug)
• Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006) - adefovir dipivoxil
• Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis - This study has been completed (Current: 23 Nov 2006) - interferon gamma-1b
• Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
• Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
• Studying Patients With Cystic Fibrosis and Other Pulmonary and Pancreatic Disorders - This study is currently recruiting patients (Current: 23 Nov 2006)
• Role of Genetic Factors in the Development of Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone (Deskar),Pirfenidone
• Segmental Bronchoalveolar Lavage - This study is currently recruiting patients (Current: 23 Nov 2006)
• Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Phase I Study of the Third Generation Adenovirus H5.001CBCFTR in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Multicenter Study of Nontuberculous Mycobacteria in Cystic Fibrosis Patients - This study has been completed (Current: 23 Nov 2006)
• Phase II Pilot Study to Compare the Bioavailability of Buffered, Enteric-Coated Ursodiol With Unmodified Ursodiol for Chronic Cholestatic Liver Disease and Cystic Fibrosis-Associated Liver Disease - This study is no longer recruiting patients (Current: 23 Nov 2006) - ursodiol
• Phase I Randomized Study of CPX for the Treatment of Adult Patients With Mild Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - CPX
• Study of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - ibuprofen
• Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - tauroursodeoxycholic acid,ursodiol
• Phase I Pilot Study of Gene Therapy for Cystic Fibrosis Using Cationic Liposome Mediated Gene Transfer - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis - This study is currently recruiting patients (Current: 23 Nov 2006) - alendronate sodium,calcium carbonate,cholecalciferol
• Phase I Randomized Study of Adeno-Associated Virus-CFTR Vector in Patients With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Adeno-associated virus-CFTR vector
• Study of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - amiloride,uridine
• Phase II Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Mucoid Exopolysaccharide Pseudomonas Aeruginosa Immune Globulin for Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - mucoid exopolysaccharide P. aeruginosa immune globulin IV
• Phase I Pilot Study of Ad5-CB-CFTR, an Adenovirus Vector Containing the Cystic Fibrosis Transmembrane Conductance Regulator Gene, in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Phase I Study of Liposome-Mediated Gene Transfer in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Phase III Randomized Study of the Inhalation of Tobramycin in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - tobramycin
• Randomized Study of Pancrelipase With Bicarbonate (PANCRECARB) Capsules in Reducing Steatorrhea in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - pancrelipase with bicarbonate
• Weight Gain in CF - This study has been completed (Current: 23 Nov 2006)
• Study of Total Energy Expenditure in Infants and Children With Moderate to Severe Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• A Study of the Safety and Efficacy of Tobramycin for Inhalation in Young Children With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - Tobramycin for Inhalation
• Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis - This study has been terminated (Current: 23 Nov 2006) - glucose,insulin,leucine
• Study of Hepatic Glucose Production and De Novo Lipogenesis in Patients With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Benefits and Risks of Newborn Screening for Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Tissue Collection From People With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Phase II Study of Growth Hormone in Children With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - growth hormone
• Study of Mycobacterial Infections - This study is currently recruiting patients (Current: 23 Nov 2006) - Clofazimine
• Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa - This study is currently recruiting patients (Current: 23 Nov 2006)
• Interferon Gamma-1b by Inhalation for the Treatment of Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - interferon gamma-1b
• Study of Interferon Gamma-1b by Injection for the Treatment of Patients With Cystic Fibrosis - This study has been terminated (Current: 23 Nov 2006) - interferon gamma-1b
• Study of INS37217 Inhalation Solution in Mild to Moderate Cystic Fibrosis Lung Disease - This study has been completed (Current: 23 Nov 2006) - denufosol tetrasodium (INS37217)
• Efficacy and Safety of 24 Weeks of Oral Treatment With BIIL 284 BS in Adult and Pediatric Patients - This study has been terminated (Current: 23 Nov 2006) - BIIL 283 BS (Amelubent)
• Oral TheraCLEC - Total in Cystic Fibrosis Subjects With Exocrine Pancreatic Insufficiency - This study has been completed (Current: 23 Nov 2006) - TheraCLEC™ – Total
• Zinc Homeostasis and Kinetics in Children With Cystic Fibrosis (CF) - This study is currently recruiting patients (Current: 23 Nov 2006) - Zinc acetate (20mg/d)
• Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - mannitol,pulmozyme,mannitol + pulmozyme
• Study of Aztreonam Lysinate for Inhalation (AI) in Cystic Fibrosis Patients With P. Aeruginosa - This study is currently recruiting patients (Current: 23 Nov 2006) - aztreonam lysinate for inhalation (AI)
• Standard Vs. Biofilm Susceptibility Testing in CF - This study is currently recruiting patients (Current: 23 Nov 2006) - IV amikacin,PO azithromycin,IV ceftazidime,PO ciprofloxacin,IV meropenem,IV piperacillin-tazobactam,IV ticarcillin-clavulanate,IV tobramycin
• Non-Invasive Ventilation and Oxygen Therapy in Cystic Fibrosis Patients With Nocturnal Oxygen Desaturation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of Alendronate to Prevent and Treat Osteoporosis in Cystic Fibrosis Patients - This study is no longer recruiting patients (Current: 23 Nov 2006) - Alendronate
• Treatment of Metabolic Alkalosis in Acute Exacerbations of Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Normal saline IV, salt tablets
• Inhaled Bicarbonate Therapy in Cystic Fibrosis - This study has been suspended (Current: 23 Nov 2006)
• Effectiveness of Pulmozyme in Infants With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Recombinant Human DNase (Pulmozyme)
• An Effectiveness, Safety, and Palatability Study of Pancrelipase Microtablets in Infants and Toddlers With Cystic Fibrosis and Fat Malabsorption - This study is no longer recruiting patients (Current: 23 Nov 2006) - pancrelipase
• Safety Study of Orally Administered Curcuminoids in Adult Subjects With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - standardized turmeric root extract
• Assessment of Inflammatory Mediators (AIM) - This study is currently recruiting patients (Current: 23 Nov 2006) - Ibuprofen
• PTC124 for Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - PTC124
• Safety and Efficacy of PTC124 for Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - PTC124
• Cystic Fibrosis and Totally Implantable Vascular Access Devices: Evaluation of the Incidence of Venous Thrombosis Related to the Catheter and Study of the Genetic and Acquired Risk Factors - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Assessing Mucociliary Clearance and Airway Liquid Volume in the CF Airway - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effect of Simvastatin on CF Airway Inflammation - This study is currently recruiting patients (Current: 23 Nov 2006) - Simvastatin treatment for 28 days
• Safety Study of Inhaled 552-02 in Cystic Fibrosis Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - 552-02
• A Study to Evaluate the Safety and Efficacy of Eurand Pancreatic Enzyme Product (PEP) in Patients With Cystic Fibrosis and Exocrine Pancreatic Insufficiency - This study is currently recruiting patients (Current: 23 Nov 2006) - Eurand PEP Capsules
• Azithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex - This study is currently recruiting patients (Current: 23 Nov 2006) - Azithromycin,Placebo
• Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. - This study is currently recruiting patients (Current: 23 Nov 2006) - Sodium Pyruvate in 0.9% Sodium Chloride Solution
• Comparison of Airway Clearance Efficacy of Two High Frequency Chest Wall Oscillation (HFCWO) Devices in Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Hydroxychloroquine in Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - hydroxychloroquine
• A Phase I Study of Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. - This study is currently recruiting patients (Current: 23 Nov 2006) - Inhaled Sodium Pyruvate
• PTC124 for the Treatment of Cystic Fibrosis - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - PTC124
• Antimicrobial Resistance in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• 18FDG- PET/CT Contribution to the Assessment of Lesion Severity in Cystic Fibrosis (CF) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
• Nasal Epithelial Cells/Blood Lymphocyte Markers for CF/CF Pulmonary Exacerbations - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Whole Body Vibration - a New Therapeutic Approach to Improve Muscle Function in CF - This study has been completed (Current: 23 Nov 2006)
• STIMUCO : Assessment of Quadriceps Muscle Electrostimulation Used in Patients Suffering From Cystic Fibrosis - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• A Randomized, Double-Blind, Three-Arm, Phase 3b Study Comparing the Safety and Efficacy of Interferon Gamma-1b With Azathioprine, and Azathioprine Alone in Patients With IPF Receiving Prednisone - This study has been terminated (Current: 23 Nov 2006) - interferon-gamma 1b,azathioprine
• An Open-Label Study of the Safety and Efficacy of Subcutaneous Recombinant Interferon-Gamma 1b (IFN-Gamma 1b) in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006) - interferon-gamma 1b
• Inhaled Iloprost in Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Iloprost Inhalation Solution (Ventavis)
• Rare Genetic Disorders of the Breathing Airways - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension - This study is currently recruiting patients (Current: 23 Nov 2006) - Sildenafil (50 mg)
• Efficacy and Safety of Oral Bosentan in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - bosentan
• Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study - This study is currently recruiting patients (Current: 23 Nov 2006) - minocycline
• BUILD 3: Bosentan Use in Interstitial Lung Disease - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - bosentan
• A Study to Evaluate Nutropin AQ for the Treatment of Growth Restriction in Children With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Nutropin AQ [somatropin (DNA origin) injection]
• An Interactive Program to Improve Care for Children With CF - This study has been completed (Current: 23 Nov 2006)
• Evaluation of a Decision Aid for Adult Cystic Fibrosis Patients Considering Bilateral Lung Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Diabetes Therapy to Improve BMI and Lung Function in CF - This study is currently recruiting patients (Current: 23 Nov 2006) - Insulin Aspart,Rapaglinide
• Macrolide Antibiotic Therapy for Patients With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Biaxin ( clarithromycin)
• Cystic Fibrosis Withdrawal of Inhaled Steroids Evaluation Study (CF WISE Study) - This study has been completed (Current: 23 Nov 2006) - Fluticasone or placebo
• Interest of Gentamicin-Induced Readthrough in Cystic Fibrosis Patients - This study has been terminated (Current: 23 Nov 2006) - Gentamicin
• Efficacy and Safety of 28 or 56 Days Treatment With Inhaled Tobramycin Nebuliser Solution for Pseudomonas Aeruginosa Infection in Children With Cystic Fibrosis. - This study is no longer recruiting patients (Current: 23 Nov 2006) - Tobramycin Nebulised Solution
• Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - sildenafil
• Tobramycin Inhalation Solution Administered by eFlow Rapid Nebulizer: Scintigraphy Study - This study is currently recruiting patients (Current: 23 Nov 2006) - Tobramycin
• Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Combination Drug Therapy for Patients With Hepatitis C - This study has been completed (Current: 23 Nov 2006) - Ribavirin
• Peginterferon Alpha-2a Maintenance Therapy for Portal Hypertension in Patients With Hepatitis C - This study is currently recruiting patients (Current: 23 Nov 2006) - Peginterferon Alpha-2a
• PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to Alpha-Interferon Plus Ribavirin (Study P02370) - This study is currently recruiting patients (Current: 23 Nov 2006) - Peginterferon alfa-2B,Ribavirin
• Effect of a Perioperative Oral Nutritional Supplementation on Patients Undergoing Hepatic Surgery for Liver Cancer. - This study is currently recruiting patients (Current: 23 Nov 2006) - Oral Impact®
• Study of Long-Term Peg Intron Vs. Colchicine in Non-Responders. - This study is currently recruiting patients (Current: 23 Nov 2006) - PEG interferon Alfa-2b; Colchicine
• Diffuse Fibrotic Lung Disease - This study has been completed (Current: 23 Nov 2006) - prednisone,cyclophosphamide,dapsone
• Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Scleroderma Lung Study - This study has been completed (Current: 23 Nov 2006) - cyclophosphamide,azathioprine
• A Multi-Centered Study of the Long-Term Effect of Salmeterol and Albuterol in Cystic Fibrosis - This study has been suspended (Current: 23 Nov 2006) - Salmeterol,Albuterol
• Growth Hormone Use in Cystic Fibrosis - a Multicenter Study - This study has been completed (Current: 23 Nov 2006) - Human recombinant growth hormone
• Idiopathic Pulmonary Fibrosis: a Case-Control Study - This study has been completed (Current: 23 Nov 2006)
• Idiopathic Pulmonary Fibrosis--Pathogenesis and Staging - SCOR in Occupational and Immunological Lung Diseases - This study has been completed (Current: 23 Nov 2006)
• Bone Health of People With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Pressure Support Ventilation During CF Exacerbations - This study has been suspended (Current: 23 Nov 2006)
• Linkage Study in Familial Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006)
• A Pilot Trial of Phenylbutyrate/Genistein Duotherapy (for Cystic Fibrosis) - This study is currently recruiting patients (Current: 23 Nov 2006) - Sodium 4-Phenylbutyrate (Buphenyl),PTI G4660 (Genistein)
• Quantification of Pulmonary Neutrophil Activity in Cystic Fibrosis Using Radiolabeled Fluorodeoxyglucose and PET Imaging - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Study in Adult and Pediatric Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - denufosol tetrasodium (INS37217) Inhalation Solution
• Gene Modifiers in Cystic Fibrosis Lung Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Genetic Modifiers of Cystic Fibrosis: Sibling Study - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma - This study is no longer recruiting patients (Current: 23 Nov 2006) - Bosentan
• Safety and Efficacy of Recombinant Adeno-Associated Virus Containing the CFTR Gene in the Treatment of Cystic Fibrosis - This study has been terminated (Current: 23 Nov 2006)
• Increased Gluconeogenesis is One Cause of Cystic Fibrosis Related Diabetes (CFRD) - This study is currently recruiting patients (Current: 23 Nov 2006) - Ibuprofen
• Comparison of Two Treatment Regimens to Reduce PA Infection in Children With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Tobramycin,Ciprofloxacin
• Study of Denufosol Tetrasodium in Patients With Cystic Fibrosis Lung Disease - This study has been completed (Current: 23 Nov 2006) - denufosol tetrasodium (INS37217)
• Tobramycin Inhalation Powder (TIP) in Cystic Fibrosis Subjects - This study is currently recruiting patients (Current: 23 Nov 2006) - Tobramycin Inhalation Powder
• A Study in Pediatric Patients With Cystic Fibrosis Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - denufosol tetrasodium (INS37217)
• Multi Breath Nitrogen Washout (MBNW) as a Measure of Small Airway Function in Patients With Respiratory Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Prevalence and Significance of Gastro-Oesophageal Reflux in Cystic Fibrosis Before and After Lung Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006) - Anti-reflux pharmacotherapy
• Prevalence and Treatment of Urinary Incontinence in Women With Cystic Fibrosis and Chronic Obstructive Pulmonary Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Mucin in Sputum of CF During Pulmonary Exacerbation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effect of Non-Invasive Ventilation in Cystic Fibrosis Patient With Chronic Respiratory Failure. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Influence of DHA-Rich Supplement on DHA-Status and Health Evolution of Patients With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Giving DHA-rich supplement versus placebo
• Serum Zn Status of Patients With Cystic Fibrosis at Diagnosis and One Year Later, Compared to a Healthy Control Group - This study has been completed (Current: 23 Nov 2006)
• Can Quantitative Ultrasound Be Used for the Evaluation of Bone Health in Adolescents and Adults With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effects of a 6-Months Physical Conditioning Program in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Mannitol Dose Response Study in Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - mannitol
• Growth Hormone Treatment Study in Children With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Nutropin AQ
• Microarray Analysis of Gene Expression in IPF - This study is currently recruiting patients (Current: 23 Nov 2006)
• Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Nasal Inhalation of Dornase Alfa (Pulmozyme) in Patients With Cystic Fibrosis and Chronic Rhinosinusitis - This study is currently recruiting patients (Current: 23 Nov 2006) - Pulmozyme
• The Effects of Long Term Inhalation of Hypertonic Saline in Subjects With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - hypertonic saline
• Efficacy of Amiloride and Hypertonic Saline in Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006) - 7% NaCl,Amiloride HCl
• Growth Hormone Use in Adolescents and Adults With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Growth Hormone
• Metabolic Abnormalities in Hispanic Children With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• A Study to Determine the Variability of a 6-Minute Walk Test in Cystic Fibrosis Subjects With Advanced Lung Disease - This study has been completed (Current: 23 Nov 2006)
• Safety and Efficacy of Pioglitazone as an Anti-Inflammatory for the Treatment of CF Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - pioglitazone
• Continuous Versus Short Infusions of Ceftazidime in Cystic Fibrosis - This study has been terminated (Current: 23 Nov 2006) - ceftazidime
• Capsule Endoscopy in Cystic Fibrosis - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Study of Denufosol Inhalation Solution in Patients With Mild Cystic Fibrosis Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - denufosol tetrasodium (INS37217) Inhalation Solution
• Blood Collection From Individuals With Lung Disease for Genetic Studies - This study is currently recruiting patients (Current: 23 Nov 2006)
• Genomic and Proteomic Analysis of Disease Progression in IPF - This study is currently recruiting patients (Current: 23 Nov 2006)
• Safety of Tobramycin Inhalation Powder (TIP) vs Tobramycin Solution for Inhalation in Patients With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Tobramycin
• A Study of the Safety and Efficacy Interferon-Gamma 1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006) - Interferon-gamma 1b
• A Study of the Safety and Clinical Effects of Interferon Gamma-1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006) - Interferon-gamma 1b
• Safety Study of Tetrathiomolybdate in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006) - Tetrathiomolybdate
• Evaluation of Patients With Idiopathic Pulmonary Fibrosis (IPF) Through an IPF Registry - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Pilot Study of Aerosol Interferon-Gamma Treatment in Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006) - Aerosol Interferon-gamma treatment
• Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - zileuton,azathioprine/prednisone
• Low-Dose Radiation to Prevent Complications of Back Surgery - This study has been completed (Current: 23 Nov 2006)
• Treatment of Idiopathic Pulmonary Fibrosis With Thalidomide - This study is currently recruiting patients (Current: 23 Nov 2006) - Thalidomide
• Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Women Who Have Undergone Radiation Therapy for Early Breast Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - hyperbaric oxygen
• Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy - This study is currently recruiting patients (Current: 23 Nov 2006) - captopril
• Liver Fibrosis in HIV-Infected Patients With Elevated Liver Enzymes on Antiretroviral Therapy - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lumbar Spinal Fibrosis and TNF Alpha Inhibition - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - TNF blocker
• The Microvascular Complications Study - This study has been completed (Current: 23 Nov 2006)
• Insulin Glargine Vs Standard Insulin Therapy - This study has been completed (Current: 23 Nov 2006) - Glargine insulin
• Development of a Breath Test for Monitoring Patients With Liver Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - 13C-Methacetin
• Pirfenidone in Treating Patients With Fibrosis Caused by Radiation Therapy for Cancer - This study has been suspended (Current: 23 Nov 2006) - pirfenidone
• IH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy for Early Breast Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - IH636 grape seed proanthocyanidin extract
• Prevention of Disease Progress in Chronic Hepatitis C Patients With Liver Fibrosis (Study P02570AM2) - This study is currently recruiting patients (Current: 23 Nov 2006) - Peginterferon alfa-2b
• Efficacy and Safety of Pentoxyphilline and Tocopherol on the Fibrosis in Patients With Chronic Hepatitis C - This study is no longer recruiting patients (Current: 23 Nov 2006) - pentoxyphilline,tocopherol
• Effects of Losartan on Hepatic Fibrogenesis in Chronic Hepatitis C - This study is no longer recruiting patients (Current: 23 Nov 2006) - Losartan
• Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Bosentan (Tracleer)
• Interest of Ribavirin in the Maintenance Treatment of Liver Fibrosis Using Low Dose Pegylated Interferon alpha2b in Patients With Chronic Hepatitis C Non Responders to Previous Antiviral Therapy. - This study is currently recruiting patients (Current: 23 Nov 2006) - Peginterferon alpha-2b + ribavirin
• Pergolide Treatment and Valvular Heart Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard Treatment - This study has been completed (Current: 23 Nov 2006) - Peginterferon alfa-2a + Ribavirin,Peginterferon alfa-2a
• Use of the Insulin Pump in Cystic Fibrosis Patients With Impaired Glucose Tolerance or CFRD and in Type 1 Diabetes Patients. - This study is no longer recruiting patients (Current: 23 Nov 2006) - Insulin
• Prevalence of Chronic Rhinosinusitis in Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Restore Claims Characterization Study - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Phase I Study of Colchicine Therapy in Childhood Hepatic Cirrhosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - colchicine
• Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis - This study has been completed (Current: 23 Nov 2006) - lactulose
• Role of Nitric Oxide in Cirrhosis: Relationship With Systemic Hemodynamics, Renal Function, Vasoactive Systems and Endotoxemia - This study is currently recruiting patients (Current: 23 Nov 2006) - N-monomethyl-L-arginine
• Peg-Intron for Prevention of Disease Progress in Chronic Hepatitis C Patients With Cirrhosis (Study P02569AM) - This study is currently recruiting patients (Current: 23 Nov 2006) - Peginterferon alfa 2-b
• Gabapentin to Treat Itch in Patients With Liver Disease - This study has been completed (Current: 23 Nov 2006) - gabapentin
• Prevention of Recurrent Hepatitis B After Liver Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006) - HBIG,Epivir,Hepsera
• Telbivudine Versus Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Telbivudine (LdT) versus Lamivudine
• Adult-to-Adult Living Donor Liver Transplantation Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Vasoconstrictors as Alternatives to Albumin After LVP (Large-Volume Paracentesis) in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006) - octreotide plus midodrine,albumin
• Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites - This study has been completed (Current: 23 Nov 2006) - Terlipressin
• A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making - This study is currently recruiting patients (Current: 23 Nov 2006)
• Albumin Administration in Patients With Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis - This study is currently recruiting patients (Current: 23 Nov 2006) - Human Albumin
• FibroScan in Patients With Hepatitis B and C Presenting for Liver Biopsy - This study is currently recruiting patients (Current: 23 Nov 2006)
• Use of NovoSeven in Active Variceal Bleeding - This study is currently recruiting patients (Current: 23 Nov 2006) - Activated recombinant human factor VII (NovoSeven®)
• Clinical Trial of Pentoxifyllin in Patient With Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006) - pentoxifyllin
• Urotensin II and Vascular Tone in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006) - urotensin II
• Diagnosis of Variceal Bleeding and Its Control in Cirrhosis - This study has been terminated (Current: 23 Nov 2006)
• TIPS With Coated Stents for Refractory Ascites in Patients With Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• DOCICAR: Cardiac Dysfunction in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Dobutamine
• A Comparison of the Drug Telbivudine (LdT) and Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis. - This study is currently recruiting patients (Current: 23 Nov 2006) - LdT (Telbivudine) and lamivudine
• Treatment of Hepatorenal Syndrome With Terlipressin Plus Albumin Vs Albumin - This study is currently recruiting patients (Current: 23 Nov 2006) - terlipressin
• Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment. - This study is currently recruiting patients (Current: 23 Nov 2006) - l-ornithine l-aspartate
• Effect of Yogurt on Minimal Hepatic Encephalopathy - This study is currently recruiting patients (Current: 23 Nov 2006) - Yogurt Supplementation
• Echocardiographic Assessment of Intrapulmonary Vasodilatation: Agitated Saline Versus Polygeline - This study is currently recruiting patients (Current: 23 Nov 2006)
• Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis - This study has been completed (Current: 23 Nov 2006) - Oral norfloxacin
• Transplant-Related Accelerated Progression of Hepatitis C - This study is currently recruiting patients (Current: 23 Nov 2006)
• Breath Test to Assess Hepatic Metabolic Reserve and to Predict Hepatic Decompensation in Cirrhotics - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Transjugular Intrahepatic Portosystemic Shunt With 8- or 10-mm Covered Stents - This study is currently recruiting patients (Current: 23 Nov 2006)
• Development of a Noninvasive Method of Evaluation of Pulmonary Inflammation in the Condensates of Exhaled Air - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Pirfenidone to Treat Hypertrophic Cardiomyopathy - This study has been completed (Current: 23 Nov 2006) - Pirfenidone
• Evaluation of Autosomal Recessive Polycystic Kidney Disease and Congenital Hepatic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Diabetes Therapy to Improve Body Mass Index (BMI) and Lung Function in Cystic Fibrosis (CF) - This study is currently recruiting patients (Current: 23 Nov 2006) - Repaglinide and insulin aspart (Novolog)
• Sirolimus for Focal Segmental Glomerulosclerosis - This study has been completed (Current: 23 Nov 2006) - Sirolimus
• Retinoids for Minimal Change Disease and Focal Segmental Glomerulosclerosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Retinoids for Podocyte Disease
• Pirfenidone to Treat Kidney Disease in Patients With Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
• Treatment of Early Systemic Sclerosis by Bosentan - This study is currently recruiting patients (Current: 23 Nov 2006) - bosentan
• Study for Treatment of Moderate or Severe, Periodic, "Cyclic", Breast Pain - This study is currently recruiting patients (Current: 23 Nov 2006) - IoGen (molecular iodine)
• Methacetin Breath Test in HCV Patients With Normal and Near-Normal ALT - This study is currently recruiting patients (Current: 23 Nov 2006)
• CMR to Assess Fibrosis in Cardiomyopathy Using Eplerenone - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Eplerenone
• The Safety and Effectiveness of Zidovudine in the Treatment of HIV-Infected Children With Mild to Moderate Symptoms - This study has been completed (Current: 23 Nov 2006) - Zidovudine
• The Role of Heart Stiff and Weak Atrium on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy - This study has been completed (Current: 23 Nov 2006)
• Anticoagulation in Liver Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Warfarin
• Pilot Study on the Use of Sirolimus to Treat Chronic Allograft Nephropathy in Children After Kidney Transplant - This study is currently recruiting patients (Current: 23 Nov 2006) - sirolimus
• Aurexis in Cystic Fibrosis Subjects Chronically Colonized With Staphylococcus Aureus in Their Lungs - This study is currently recruiting patients (Current: 23 Nov 2006) - Aurexis® (tefibazumab)
• Repaglinide for Adolescents With Cystic Fibrosis-Related Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Repaglinide and Insulin
• Antifibrotic Activity Of GI262570 In Chronic Hepatitis C Subjects - This study is currently recruiting patients (Current: 23 Nov 2006) - GI262570
• Database of Interstitial Lung Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
• Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion - This study is currently recruiting patients (Current: 23 Nov 2006)
• Allograft Fibrosis Following Pediatric Cardiac Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Ocular Surface Changes in Patients With Cystic Fibrosis - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Pegylated Interferon and Ribavirin in Hepatitis C Virus Infection After Liver Transplantation. - This study has been completed (Current: 23 Nov 2006) - Pegylated interferon and ribavirin
• Non-Invasive Evaluation of Hepatic Fibrosis in Patients With the Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pulmonary Rehabilitation in Interstitial Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Multicenter Study on Fibrotic Valvular Heart Disease in Patients With Parkinson's Disease Treated With Dopamine Agonists - This study is currently recruiting patients (Current: 23 Nov 2006)
• Repository for Inherited Eye Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
• Herpesvirus in Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Liver Fibrosis in Patients Transplanted for Hepatitis C Receiving Either Cyclosporine Microemulsion or Tacrolimus - This study is currently recruiting patients (Current: 23 Nov 2006) - Cyclosporine microemulsion and tacrolimus
• Treating Nonalcoholic Steatohepatitis with Pioglitazone - This study is currently recruiting patients (Current: 23 Nov 2006) - Actos (Pioglitazone)
• Treating Nonalcoholic Steatohepatitis (NASH) with Metformin - This study is currently recruiting patients (Current: 23 Nov 2006) - Metformin
• SALT Trial Study of Ascending Levels of Tolvaptan in Hyponatremia - This study has been completed (Current: 23 Nov 2006) - tolvaptan
• SALT-2 Trial Study of Ascending Levels of Tolvaptan in Hyponatremia - This study is no longer recruiting patients (Current: 23 Nov 2006) - Tolvaptan
• The Use of Drugs to Improve Kidney Function in Patients With Liver and Kidney Dysfunction - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Midodrine, albumin, octreotide LAR
• Weight Management in Nonalcoholic Steatohepatitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Selenium Supplementation of Patients With Cirrhosis - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Selenium Supplements (essential nutrient)
• A 6-Month Efficacy, Safety and Tolerability Study of Rifaximin In Preventing Hepatic Encephalopathy - This study is currently recruiting patients (Current: 23 Nov 2006) - Rifaximin
• Efficacy and Safety of Endoscopic Injection of Fibrin Sealant Versus Endoscopic Ligature for Bleeding Esophageal Varices - This study is no longer recruiting patients (Current: 23 Nov 2006) - Fibrin Sealant
• N-Butyl-2-Cyanoacrylate Injection Versus Band Ligation for Gastric Variceal Hemorrhage - This study has been completed (Current: 23 Nov 2006)
• Thymosin Plus PEG-Interferon in Hepatitis C Patients With Cirrhosis Who Did Not Respond to Interferon or Interferon Plus Ribavirin - This study is no longer recruiting patients (Current: 23 Nov 2006) - thymalfasin (thymosin alpha 1),PEGinterferon alfa-2a

Drugs used in Clinical Trials for Fibrosis

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Fibrosis:

• 13C-Methacetin - Development of a Breath Test for Monitoring Patients With Liver Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• 552-02 - Safety Study of Inhaled 552-02 in Cystic Fibrosis Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• 7% NaCl - Efficacy of Amiloride and Hypertonic Saline in Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Activated recombinant human factor VII (NovoSeven®) - Use of NovoSeven in Active Variceal Bleeding - This study is currently recruiting patients (Current: 23 Nov 2006)
• Actos (Pioglitazone) - Treating Nonalcoholic Steatohepatitis with Pioglitazone - This study is currently recruiting patients (Current: 23 Nov 2006)
• Adefovir Dipivoxil - Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Adeno-associated virus-CFTR vector - Phase I Randomized Study of Adeno-Associated Virus-CFTR Vector in Patients With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Aerosol Interferon-gamma treatment - A Pilot Study of Aerosol Interferon-Gamma Treatment in Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Albumin - Vasoconstrictors as Alternatives to Albumin After LVP (Large-Volume Paracentesis) in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Albuterol - A Multi-Centered Study of the Long-Term Effect of Salmeterol and Albuterol in Cystic Fibrosis - This study has been suspended (Current: 23 Nov 2006)
• Alendronate Sodium - Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Alendronate - Study of Alendronate to Prevent and Treat Osteoporosis in Cystic Fibrosis Patients - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Amiloride HCl - Efficacy of Amiloride and Hypertonic Saline in Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Amiloride - Study of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Anti-reflux pharmacotherapy - The Prevalence and Significance of Gastro-Oesophageal Reflux in Cystic Fibrosis Before and After Lung Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Aurexis® (tefibazumab) - Aurexis in Cystic Fibrosis Subjects Chronically Colonized With Staphylococcus Aureus in Their Lungs - This study is currently recruiting patients (Current: 23 Nov 2006)
• Azathioprine/Prednisone - Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Azathioprine - A Randomized, Double-Blind, Three-Arm, Phase 3b Study Comparing the Safety and Efficacy of Interferon Gamma-1b With Azathioprine, and Azathioprine Alone in Patients With IPF Receiving Prednisone - This study has been terminated (Current: 23 Nov 2006)
• Azathioprine - Scleroderma Lung Study - This study has been completed (Current: 23 Nov 2006)
• Azithromycin - Azithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex - This study is currently recruiting patients (Current: 23 Nov 2006)
• Aztreonam Lysinate For Inhalation (Ai) - International Safety and Efficacy Study of Aztreonam Lysinate for Inhalation (AI) in Cystic Fibrosis Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• Aztreonam Lysinate For Inhalation (Ai) - Safety and Efficacy Study of Aztreonam Lysinate for Inhalation (AI) in Cystic Fibrosis Patients With P. Aeruginosa - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Aztreonam Lysinate For Inhalation (Ai) - Study of Aztreonam Lysinate for Inhalation (AI) in Cystic Fibrosis Patients With P. Aeruginosa - This study is currently recruiting patients (Current: 23 Nov 2006)
• BIIL 283 BS (Amelubent) - Efficacy and Safety of 24 Weeks of Oral Treatment With BIIL 284 BS in Adult and Pediatric Patients - This study has been terminated (Current: 23 Nov 2006)
• Biaxin ( clarithromycin) - Macrolide Antibiotic Therapy for Patients With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Bosentan (Tracleer) - Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Bosentan - BUILD 3: Bosentan Use in Interstitial Lung Disease - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Bosentan - Efficacy and Safety of Oral Bosentan in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Bosentan - Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Bosentan - Treatment of Early Systemic Sclerosis by Bosentan - This study is currently recruiting patients (Current: 23 Nov 2006)
• CPX - Phase I Randomized Study of CPX for the Treatment of Adult Patients With Mild Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Calcium Carbonate - Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Captopril - Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ceftazidime - Continuous Versus Short Infusions of Ceftazidime in Cystic Fibrosis - This study has been terminated (Current: 23 Nov 2006)
• Cholecalciferol - Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ciprofloxacin - Comparison of Two Treatment Regimens to Reduce PA Infection in Children With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Clofazimine - Study of Mycobacterial Infections - This study is currently recruiting patients (Current: 23 Nov 2006)
• Colchicine - Phase I Study of Colchicine Therapy in Childhood Hepatic Cirrhosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Cyclophosphamide - Diffuse Fibrotic Lung Disease - This study has been completed (Current: 23 Nov 2006)
• Cyclophosphamide - Scleroderma Lung Study - This study has been completed (Current: 23 Nov 2006)
• Cyclosporine microemulsion and tacrolimus - Liver Fibrosis in Patients Transplanted for Hepatitis C Receiving Either Cyclosporine Microemulsion or Tacrolimus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Dapsone - Diffuse Fibrotic Lung Disease - This study has been completed (Current: 23 Nov 2006)
• Denufosol Tetrasodium (Ins37217) Inhalation Solution - A Study in Adult and Pediatric Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Denufosol Tetrasodium (Ins37217) Inhalation Solution - Study of Denufosol Inhalation Solution in Patients With Mild Cystic Fibrosis Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Denufosol Tetrasodium (Ins37217) - A Study in Pediatric Patients With Cystic Fibrosis Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Denufosol Tetrasodium (Ins37217) - Study of Denufosol Tetrasodium in Patients With Cystic Fibrosis Lung Disease - This study has been completed (Current: 23 Nov 2006)
• Denufosol Tetrasodium (Ins37217) - Study of INS37217 Inhalation Solution in Mild to Moderate Cystic Fibrosis Lung Disease - This study has been completed (Current: 23 Nov 2006)
• Dobutamine - DOCICAR: Cardiac Dysfunction in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Epivir - Prevention of Recurrent Hepatitis B After Liver Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Eplerenone - CMR to Assess Fibrosis in Cardiomyopathy Using Eplerenone - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Etanercept - Study Evaluating the Safety and Efficacy of Etanercept in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Eurand PEP Capsules - A Study to Evaluate the Safety and Efficacy of Eurand Pancreatic Enzyme Product (PEP) in Patients With Cystic Fibrosis and Exocrine Pancreatic Insufficiency - This study is currently recruiting patients (Current: 23 Nov 2006)
• FG-3019 - Safety and Tolerability Study of FG-3019 in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Fibrin Sealant - Efficacy and Safety of Endoscopic Injection of Fibrin Sealant Versus Endoscopic Ligature for Bleeding Esophageal Varices - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Fluticasone or placebo - Cystic Fibrosis Withdrawal of Inhaled Steroids Evaluation Study (CF WISE Study) - This study has been completed (Current: 23 Nov 2006)
• GC1008, Human Anti-Transforming Growth Factor-b 1, 2, 3 mAb - Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study is currently recruiting patients (Current: 23 Nov 2006)
• GI262570 - Antifibrotic Activity Of GI262570 In Chronic Hepatitis C Subjects - This study is currently recruiting patients (Current: 23 Nov 2006)
• Gabapentin - Gabapentin to Treat Itch in Patients With Liver Disease - This study has been completed (Current: 23 Nov 2006)
• Gentamicin - Interest of Gentamicin-Induced Readthrough in Cystic Fibrosis Patients - This study has been terminated (Current: 23 Nov 2006)
• Giving DHA-rich supplement versus placebo - Influence of DHA-Rich Supplement on DHA-Status and Health Evolution of Patients With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Glargine insulin - Insulin Glargine Vs Standard Insulin Therapy - This study has been completed (Current: 23 Nov 2006)
• Glucose - Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis - This study has been terminated (Current: 23 Nov 2006)
• Growth Hormone - Growth Hormone Use in Adolescents and Adults With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Growth Hormone - Phase II Study of Growth Hormone in Children With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• HBIG - Prevention of Recurrent Hepatitis B After Liver Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Hepsera - Prevention of Recurrent Hepatitis B After Liver Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Human Albumin - Albumin Administration in Patients With Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Human recombinant growth hormone - Growth Hormone Use in Cystic Fibrosis - a Multicenter Study - This study has been completed (Current: 23 Nov 2006)
• Hydroxychloroquine - Hydroxychloroquine in Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Hyperbaric Oxygen - Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Women Who Have Undergone Radiation Therapy for Early Breast Cancer - This study is currently recruiting patients (Current: 23 Nov 2006)
• Hypertonic Saline - The Effects of Long Term Inhalation of Hypertonic Saline in Subjects With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• IH636 grape seed proanthocyanidin extract - IH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy for Early Breast Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
• IV amikacin - Standard Vs. Biofilm Susceptibility Testing in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• IV ceftazidime - Standard Vs. Biofilm Susceptibility Testing in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• IV meropenem - Standard Vs. Biofilm Susceptibility Testing in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• IV piperacillin-tazobactam - Standard Vs. Biofilm Susceptibility Testing in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• IV ticarcillin-clavulanate - Standard Vs. Biofilm Susceptibility Testing in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• IV tobramycin - Standard Vs. Biofilm Susceptibility Testing in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ibuprofen - Assessment of Inflammatory Mediators (AIM) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ibuprofen - Increased Gluconeogenesis is One Cause of Cystic Fibrosis Related Diabetes (CFRD) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ibuprofen - Study of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Iloprost Inhalation Solution (Ventavis) - Inhaled Iloprost in Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Imatinib Mesylate (Gleevec) - Gleevec Idiopathic Pulmonary Fibrosis (IPF) Study - This study has been completed (Current: 23 Nov 2006)
• Inhaled Sodium Pyruvate - A Phase I Study of Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Aspart - Diabetes Therapy to Improve BMI and Lung Function in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin - Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis - This study has been terminated (Current: 23 Nov 2006)
• Insulin - Use of the Insulin Pump in Cystic Fibrosis Patients With Impaired Glucose Tolerance or CFRD and in Type 1 Diabetes Patients. - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Interferon Gamma-1B - Interferon Gamma-1b by Inhalation for the Treatment of Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Interferon Gamma-1B - Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis - This study has been completed (Current: 23 Nov 2006)
• Interferon Gamma-1B - Study of Interferon Gamma-1b by Injection for the Treatment of Patients With Cystic Fibrosis - This study has been terminated (Current: 23 Nov 2006)
• Interferon gamma-1b ("Actimmune") - The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Interferon gamma-1b - An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Interferon-Gamma 1B - A Randomized, Double-Blind, Three-Arm, Phase 3b Study Comparing the Safety and Efficacy of Interferon Gamma-1b With Azathioprine, and Azathioprine Alone in Patients With IPF Receiving Prednisone - This study has been terminated (Current: 23 Nov 2006)
• Interferon-Gamma 1B - An Open-Label Study of the Safety and Efficacy of Subcutaneous Recombinant Interferon-Gamma 1b (IFN-Gamma 1b) in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006)
• Interferon-gamma 1b - A Study of the Safety and Clinical Effects of Interferon Gamma-1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006)
• Interferon-gamma 1b - A Study of the Safety and Efficacy Interferon-Gamma 1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006)
• IoGen (molecular iodine) - Study for Treatment of Moderate or Severe, Periodic, "Cyclic", Breast Pain - This study is currently recruiting patients (Current: 23 Nov 2006)
• L-Ornithine L-Aspartate - Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lactulose - Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis - This study has been completed (Current: 23 Nov 2006)
• LdT (Telbivudine) and lamivudine - A Comparison of the Drug Telbivudine (LdT) and Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Leucine - Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis - This study has been terminated (Current: 23 Nov 2006)
• Losartan - Effects of Losartan on Hepatic Fibrogenesis in Chronic Hepatitis C - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Mannitol + Pulmozyme - Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Mannitol - Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Mannitol - Mannitol Dose Response Study in Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Metformin - Treating Nonalcoholic Steatohepatitis (NASH) with Metformin - This study is currently recruiting patients (Current: 23 Nov 2006)
• Midodrine, albumin, octreotide LAR - The Use of Drugs to Improve Kidney Function in Patients With Liver and Kidney Dysfunction - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Minocycline - Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Mucoid Exopolysaccharide P. Aeruginosa Immune Globulin Iv - Phase II Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Mucoid Exopolysaccharide Pseudomonas Aeruginosa Immune Globulin for Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• N-monomethyl-L-arginine - Role of Nitric Oxide in Cirrhosis: Relationship With Systemic Hemodynamics, Renal Function, Vasoactive Systems and Endotoxemia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Normal saline IV, salt tablets - Treatment of Metabolic Alkalosis in Acute Exacerbations of Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Nutropin AQ [somatropin (DNA origin) injection] - A Study to Evaluate Nutropin AQ for the Treatment of Growth Restriction in Children With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Nutropin AQ - Growth Hormone Treatment Study in Children With Cystic Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Octreotide Plus Midodrine - Vasoconstrictors as Alternatives to Albumin After LVP (Large-Volume Paracentesis) in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Oral Impact® - Effect of a Perioperative Oral Nutritional Supplementation on Patients Undergoing Hepatic Surgery for Liver Cancer. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Oral norfloxacin - Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis - This study has been completed (Current: 23 Nov 2006)
• PEG interferon Alfa-2b; Colchicine - Study of Long-Term Peg Intron Vs. Colchicine in Non-Responders. - This study is currently recruiting patients (Current: 23 Nov 2006)
• PEGinterferon alfa-2a - Thymosin Plus PEG-Interferon in Hepatitis C Patients With Cirrhosis Who Did Not Respond to Interferon or Interferon Plus Ribavirin - This study is no longer recruiting patients (Current: 23 Nov 2006)
• PO azithromycin - Standard Vs. Biofilm Susceptibility Testing in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• PO ciprofloxacin - Standard Vs. Biofilm Susceptibility Testing in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• PTC124 - PTC124 for Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• PTC124 - PTC124 for the Treatment of Cystic Fibrosis - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• PTC124 - Safety and Efficacy of PTC124 for Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• PTI G4660 (Genistein) - A Pilot Trial of Phenylbutyrate/Genistein Duotherapy (for Cystic Fibrosis) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pancrelipase With Bicarbonate - Randomized Study of Pancrelipase With Bicarbonate (PANCRECARB) Capsules in Reducing Steatorrhea in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Pancrelipase - An Effectiveness, Safety, and Palatability Study of Pancrelipase Microtablets in Infants and Toddlers With Cystic Fibrosis and Fat Malabsorption - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Peg-interferon alpha 2b (drug) - Efficacy of Prazosin Versus Placebo Associated With Peg-Interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Peginterferon Alpha-2a - Peginterferon Alpha-2a Maintenance Therapy for Portal Hypertension in Patients With Hepatitis C - This study is currently recruiting patients (Current: 23 Nov 2006)
• Peginterferon alfa 2-b - Peg-Intron for Prevention of Disease Progress in Chronic Hepatitis C Patients With Cirrhosis (Study P02569AM) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Peginterferon alfa-2B - PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to Alpha-Interferon Plus Ribavirin (Study P02370) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Peginterferon alfa-2a + Ribavirin - Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard Treatment - This study has been completed (Current: 23 Nov 2006)
• Peginterferon alfa-2a - Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard Treatment - This study has been completed (Current: 23 Nov 2006)
• Peginterferon alfa-2b - Prevention of Disease Progress in Chronic Hepatitis C Patients With Liver Fibrosis (Study P02570AM2) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Peginterferon alpha-2b + ribavirin - Interest of Ribavirin in the Maintenance Treatment of Liver Fibrosis Using Low Dose Pegylated Interferon alpha2b in Patients With Chronic Hepatitis C Non Responders to Previous Antiviral Therapy. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pegylated interferon and ribavirin - Pegylated Interferon and Ribavirin in Hepatitis C Virus Infection After Liver Transplantation. - This study has been completed (Current: 23 Nov 2006)
• Pentoxifyllin - Clinical Trial of Pentoxifyllin in Patient With Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pentoxyphilline - Efficacy and Safety of Pentoxyphilline and Tocopherol on the Fibrosis in Patients With Chronic Hepatitis C - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pioglitazone - Safety and Efficacy of Pioglitazone as an Anti-Inflammatory for the Treatment of CF Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pirfenidone (Deskar) - Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pirfenidone - Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pirfenidone - Pirfenidone for the Treatment of Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis (PF/IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pirfenidone - Pirfenidone in Treating Patients With Fibrosis Caused by Radiation Therapy for Cancer - This study has been suspended (Current: 23 Nov 2006)
• Pirfenidone - Pirfenidone to Treat Hypertrophic Cardiomyopathy - This study has been completed (Current: 23 Nov 2006)
• Pirfenidone - Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pirfenidone - Pirfenidone to Treat Kidney Disease in Patients With Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pirfenidone - Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pirfenidone - Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Placebo - Azithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex - This study is currently recruiting patients (Current: 23 Nov 2006)
• Prazosin (drug) - Efficacy of Prazosin Versus Placebo Associated With Peg-Interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Prednisone - Diffuse Fibrotic Lung Disease - This study has been completed (Current: 23 Nov 2006)
• Pulmozyme - Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pulmozyme - Nasal Inhalation of Dornase Alfa (Pulmozyme) in Patients With Cystic Fibrosis and Chronic Rhinosinusitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rapaglinide - Diabetes Therapy to Improve BMI and Lung Function in CF - This study is currently recruiting patients (Current: 23 Nov 2006)
• Recombinant Human DNase (Pulmozyme) - Effectiveness of Pulmozyme in Infants With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Repaglinide and Insulin - Repaglinide for Adolescents With Cystic Fibrosis-Related Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Repaglinide and insulin aspart (Novolog) - Diabetes Therapy to Improve Body Mass Index (BMI) and Lung Function in Cystic Fibrosis (CF) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Retinoids for Podocyte Disease - Retinoids for Minimal Change Disease and Focal Segmental Glomerulosclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ribavirin (drug) - Efficacy of Prazosin Versus Placebo Associated With Peg-Interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ribavirin - Combination Drug Therapy for Patients With Hepatitis C - This study has been completed (Current: 23 Nov 2006)
• Ribavirin - PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to Alpha-Interferon Plus Ribavirin (Study P02370) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rifaximin - A 6-Month Efficacy, Safety and Tolerability Study of Rifaximin In Preventing Hepatic Encephalopathy - This study is currently recruiting patients (Current: 23 Nov 2006)
• Salmeterol - A Multi-Centered Study of the Long-Term Effect of Salmeterol and Albuterol in Cystic Fibrosis - This study has been suspended (Current: 23 Nov 2006)
• Selenium Supplements (essential nutrient) - Selenium Supplementation of Patients With Cirrhosis - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Sildenafil (50 mg) - Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sildenafil - Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Simvastatin treatment for 28 days - Effect of Simvastatin on CF Airway Inflammation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sirolimus - Pilot Study on the Use of Sirolimus to Treat Chronic Allograft Nephropathy in Children After Kidney Transplant - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sirolimus - Sirolimus for Focal Segmental Glomerulosclerosis - This study has been completed (Current: 23 Nov 2006)
• Sodium 4-Phenylbutyrate (Buphenyl) - A Pilot Trial of Phenylbutyrate/Genistein Duotherapy (for Cystic Fibrosis) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sodium Pyruvate in 0.9% Sodium Chloride Solution - Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Standardized Turmeric Root Extract - Safety Study of Orally Administered Curcuminoids in Adult Subjects With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• TNF blocker - Lumbar Spinal Fibrosis and TNF Alpha Inhibition - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Tauroursodeoxycholic Acid - Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Telbivudine (LdT) versus Lamivudine - Telbivudine Versus Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Terlipressin - Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites - This study has been completed (Current: 23 Nov 2006)
• Terlipressin - Treatment of Hepatorenal Syndrome With Terlipressin Plus Albumin Vs Albumin - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tetrathiomolybdate - Safety Study of Tetrathiomolybdate in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Thalidomide - Treatment of Idiopathic Pulmonary Fibrosis With Thalidomide - This study is currently recruiting patients (Current: 23 Nov 2006)
• TheraCLEC™ – Total - Oral TheraCLEC - Total in Cystic Fibrosis Subjects With Exocrine Pancreatic Insufficiency - This study has been completed (Current: 23 Nov 2006)
• Thymalfasin (Thymosin Alpha 1) - Thymosin Plus PEG-Interferon in Hepatitis C Patients With Cirrhosis Who Did Not Respond to Interferon or Interferon Plus Ribavirin - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Tobramycin Inhalation Powder - Tobramycin Inhalation Powder (TIP) in Cystic Fibrosis Subjects - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tobramycin Nebulised Solution - Efficacy and Safety of 28 or 56 Days Treatment With Inhaled Tobramycin Nebuliser Solution for Pseudomonas Aeruginosa Infection in Children With Cystic Fibrosis. - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Tobramycin for Inhalation - A Study of the Safety and Efficacy of Tobramycin for Inhalation in Young Children With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Tobramycin - Comparison of Two Treatment Regimens to Reduce PA Infection in Children With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tobramycin - Phase III Randomized Study of the Inhalation of Tobramycin in Patients With Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Tobramycin - Safety of Tobramycin Inhalation Powder (TIP) vs Tobramycin Solution for Inhalation in Patients With Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tobramycin - Tobramycin Inhalation Solution Administered by eFlow Rapid Nebulizer: Scintigraphy Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tocopherol - Efficacy and Safety of Pentoxyphilline and Tocopherol on the Fibrosis in Patients With Chronic Hepatitis C - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Tolvaptan - SALT Trial Study of Ascending Levels of Tolvaptan in Hyponatremia - This study has been completed (Current: 23 Nov 2006)
• Tolvaptan - SALT-2 Trial Study of Ascending Levels of Tolvaptan in Hyponatremia - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Uridine - Study of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis - This study has been completed (Current: 23 Nov 2006)
• Urotensin Ii - Urotensin II and Vascular Tone in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ursodiol - Phase II Pilot Study to Compare the Bioavailability of Buffered, Enteric-Coated Ursodiol With Unmodified Ursodiol for Chronic Cholestatic Liver Disease and Cystic Fibrosis-Associated Liver Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Ursodiol - Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Warfarin - Anticoagulation in Liver Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Yogurt Supplementation - Effect of Yogurt on Minimal Hepatic Encephalopathy - This study is currently recruiting patients (Current: 23 Nov 2006)
• Zidovudine - The Safety and Effectiveness of Zidovudine in the Treatment of HIV-Infected Children With Mild to Moderate Symptoms - This study has been completed (Current: 23 Nov 2006)
• Zileuton - Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Zinc acetate (20mg/d) - Zinc Homeostasis and Kinetics in Children With Cystic Fibrosis (CF) - This study is currently recruiting patients (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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