Prevalence and Incidence of Friedreich's ataxia

Friedreich's ataxia: Rare Disease

Friedreich's ataxia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Friedreich's ataxia, or a subtype of Friedreich's ataxia, affects less than 200,000 people in the US population.

Friedreich's ataxia Prevalence: Book Excerpts

• Ataxia - epidemiology - Ataxia

Prevalence/Incidence of Friedreich's ataxia: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Friedreich's ataxia.

Ataxia: Ataxia - epidemiology
(The 5-Minute Pediatric Consult)

Ataxia - incidence

• ~1 in 1,000 children develop acute ataxia following varicella infection.
• The most common congenital cerebellar syndromes are caused by perinatal trauma and hypercoagulable or hemorrhagic vascular events (“ataxic cerebral palsy”). Fetal stroke is estimated to complicate 1 in 4,000 full-term births. The Dandy-Walker syndrome and structural cerebellar abnormalities are rarer causes of congenital cerebellar dysfunction.
• Metabolic/heredodegenerative causes are rare.
  • Friedreich ataxia incidence is 2–4 in 100,000.
  • Ataxia with oculomotor apraxia occurrence is near 5 in 100,000.

Ataxia - prevalence

Cerebellar medulloblastomas represent 20% of pediatric primary brain tumors (associated with (ataxia-telangiectasia, basal cell nevus syndrome). Cerebellar astrocytomas, fourth ventricle ependymomas, and brainstem gliomas are also more common in children than in adults.

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008

About prevalence and incidence statistics:

The term 'prevalence' of Friedreich's ataxia usually refers to the estimated population of people who are managing Friedreich's ataxia at any given time. The term 'incidence' of Friedreich's ataxia refers to the annual diagnosis rate, or the number of new cases of Friedreich's ataxia diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.

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