CONFIRMING DIAGNOSIS Esophagogastroduodenoscopy or gastroscopy (with biopsy) confirms gastritis when done before lesions heal (usually within 24 hours). This test is contraindicated after ingestion of a corrosive agent.
Laboratory analyses can detect occult blood in vomitus or stool (or both) if the patient has gastric bleeding. Hemoglobin level and hematocrit are decreased if the patient has developed anemia from bleeding.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Vomiting:
History and physical examination
(Professional Guide to Signs & Symptoms (Fifth Edition))
Ask your patient to describe the onset, duration, and intensity of his vomiting. What started it? What makes it subside? If possible, collect, measure, and inspect the character of the vomitus. (See Vomitus: Characteristics and causes.) Explore any associated complaints, particularly nausea, abdominal pain, anorexia and weight loss, changes in bowel elimination patterns or the appearance of stools, excessive belching or flatus, and bloating or fullness.
Obtain a medical history, noting GI, endocrine, and metabolic disorders; recent infections; and cancer, including chemotherapy or radiation therapy. Ask about current medication use and alcohol consumption. If the patient is a female of childbearing age, ask if she is or could be pregnant and which contraceptive method she uses.
Inspect the abdomen for distention, and auscultate for bowel sounds and bruits. Palpate for rigidity and tenderness, and test for rebound tenderness. Next, palpate and percuss the liver for enlargement. Assess other body systems as appropriate.
During the examination, keep in mind that projectile vomiting unaccompanied by nausea may indicate increased intracranial pressure, a life-threatening emergency. If this occurs in a patient with a CNS injury, quickly check his vital signs. Be alert for widened pulse pressure or bradycardia.
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Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006
Nausea and Vomiting:
History.
(The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter)
As is usually the case in clinical practice, most diagnoses will be made by history and confirmed by physical examination and laboratory studies. Key points in the history include the following:
A. Are the symptoms acute, chronic, or recurrent?
B. If vomiting is the predominant feature, consider GI infection, reflux, gastritis, or ulcer.
C. Nausea as the predominant feature often results from systemic problems.
D. Is there a history of travel, drinking unsafe water, or eating unusual or uncooked food?
E. Is there a history of fevers or chills (Chapter 2.6.)?
F. Are general systemic symptoms or signs such as edema, discolored urine or jaundice, fatigue, weight loss or anorexia, headache, or blurred vision present?
G. Are psychiatric symptoms present?
H. Is the patient taking any medications?
I. Is diarrhea present?
J. Is there abdominal pain? The presence of abdominal pain raises some important and potentially serious possibilities:
1. Common problems presenting with abdominal pain and vomiting include cholecystitis, appendicitis, gastritis or ulcer, hepatitis, small bowel obstruction, inferior myocardial infarction or ischemia, renal colic, peritonitis, pancreatitis, food poisoning, and complications of pregnancy.
2. Uncommon problems presenting with abdominal pain and vomiting include diabetic ketoacidosis, drug withdrawal, uremia, and vasculitis or abdominal migraine.
3. Rare problems presenting with abdominal pain and vomiting include porphyria, lead intoxication, adrenal insufficiency, hyperlipidemia, abdominal epilepsy, glaucoma, hypercalcemia, and acute hemolysis.
Physical examination.
A directed physical examination is dictated by the findings on history, but the following are areas of key importance:
A. Vital signs. Focus on presence of fever, pulse, and blood pressure to assess hydration, and respiratory rate to look for acidosis-related hyperventilation.
B. Skin, eyes, mucous membranes. Look for dehydration and signs of jaundice.
C. Signs of systemic infection. Pay special attention to examining the lung and the costovertebral angle for tenderness.
D. A detailed abdominal examination should include inspection, auscultation, palpation, percussion, areas of tenderness, rebound, guarding, hepatomegaly, Murphy’s sign, stool for occult blood, and bimanual pelvic examination.
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Source: The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter, 2000
Nausea/Vomiting:
Differential Overview
(Field Guide to Bedside Diagnosis)
Presenting Symptom
❑ Gastroesophageal reflux
❑ Pregnancy
❑ Psychogenic
❑ Bulimia
❑ Rumination
❑ Diabetic ketoacidosis
❑ Hepatitis
❑ Inferior myocardial infarction
❑ Uremia
❑ Adrenal insufficiency
With Abdominal Pain
❑ Viral gastroenteritis
❑ Food poisoning
❑ Peptic ulcer disease
❑ Renal colic
❑ Pancreatitis
❑ Pyelonephritis
❑ Appendicitis
❑ Cholecystitis
❑ Small bowel obstruction
❑ Peritonitis
With Neurologic Signs
❑ Migraine headache
❑ Vestibular disturbance
❑ Autonomic dysfunction
❑ Increased intracranial pressure
❑ Hypercalcemia
❑ Cerebellar hemorrhage
Diagnostic Approach
Neurological vomiting may be projectile (forceful emesis without prior nausea), positional, or associated with other neurological signs. Central vomiting (chemoreceptor trigger zone stimulation, usually caused by toxins) is alleviated by antidopaminergic medications, which do not work well when treating nausea due to mechanical causes such as obstruction.
Early morning nausea suggests pregnancy or metabolic causes (e.g., uremia). Vomiting of a large amount of undigested food 4 to 6 hours after eating is consistent with gastric retention resulting from pyloric obstruction
or gastroparesis or to esophageal disorders such as achalasia or Zencker diverticulum. Feculent vomiting suggests intestinal obstruction or gastrocolic fistula.
» READ BOOK EXCERPT ONLINE »
Source: Field Guide to Bedside Diagnosis, 2007
Gastritis:
Diagnosis
(Handbook of Diseases)
The following tests are usually included to diagnose gastritis:
❑ Fecal occult blood test can detect occult blood in vomitus and stools if the patient has gastric bleeding.
❑ Hemoglobin level and hematocrit are low if significant bleeding has occurred.
❑ Upper GI endoscopy with biopsy confirms the diagnosis when performed within 24 hours of bleeding. An upper GI series may also be performed to exclude serious lesions.
Clinical tip Upper endoscopy is contraindicated after ingestion of a corrosive agent.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Vomiting:
History
(Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series)
Ask the patient to describe the onset, duration, and intensity of his vomiting. What started the vomiting? What makes it subside? If possible, collect, measure, and inspect the character of the vomitus. (See Vomitus: Characteristics and causes.) Explore associated complaints, particularly nausea, abdominal pain, anorexia and weight loss, changes in bowel habits or stools, excessive belching or flatus, and bloating or fullness.
Obtain a medical history, noting GI, endocrine, and metabolic disorders; recent infections; and cancer, including chemotherapy or radiation therapy. Ask about current medication use and alcohol consumption. If the patient is a female of childbearing age, ask if she is or could be pregnant. Ask which contraceptive method she’s using.
Physical examination
Inspect the abdomen for distention, and auscultate for bowel sounds and bruits. Palpate for rigidity and tenderness, and test for rebound tenderness. Next, palpate and percuss the liver for enlargement. Assess other body systems as appropriate.
During the examination, keep in mind that projectile vomiting unaccompanied by nausea may indicate increased intracranial pressure (ICP), a life-threatening emergency. If this occurs in a patient with a CNS injury, you should quickly check his vital signs. Stay alert for widened pulse pressure or bradycardia.
» READ BOOK EXCERPT ONLINE »
Source: Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series, 2007
Vomiting:
History
(Signs & Symptoms: A 2-in-1 Reference for Nurses)
Ask your patient to describe the onset, duration, and intensity of his vomiting. What started the vomiting? What makes it subside? If possible, collect, measure, and inspect the character of the vomitus. (See Vomitus: Characteristics and causes, page 700.) Explore any associated complaints, particularly nausea, abdominal pain, anorexia and weight loss, changes in bowel habits or stools, excessive belching or flatus, and bloating or fullness.
Obtain a medical history, noting GI, endocrine, and metabolic disorders; recent infections; and cancer, including chemotherapy or radiation therapy. Ask about current medication use and alcohol consumption. If the patient is a female of childbearing age, ask if she is or could be pregnant. Ask which contraceptive method she’s using.
» READ BOOK EXCERPT ONLINE »
Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007
Regurgitation and Vomiting:
Clinical Features and Diagnosis: Regurgitation
(The Diagnostic Approach to Symptoms and Signs in Pediatrics)
Normal Variations
In infants,milk may flow from mouth during or after feeding with little effortor distress.Common causes include overfeeding,air swallowed during feeding, crying, or coughing.Physical exam is normal and weightgain is adequate. History and physical exam are diagnostic. Gastroesophageal Reflux
Is the spontaneouspassage of stomach contents into esophagus.Common finding in many infants. Maybegin by a few weeks of age and usually resolves by 8–12mos of age. Infant is otherwise asymptomatic and has normal weightgain. No testing is required in this clinical circumstance.Gastroesophageal reflux disease refersto infants with regurgitation and vomiting associated with poorweight gain; respiratory symptoms (e.g., wheezing, hoarseness, orapnea); or esophagitis. Upper GI series is valuable to exclude anyanatomic abnormality. Esophageal pH probe study can quantitate frequencyand duration of acid reflux episodes. Endoscopy with biopsy shouldbe performed if esophagitis is suspected. Esophageal Disorders
Congenital Anomalies
Esophageal Atresia with or without Tracheoesophageal Fistula
Esophagealatresia usually exists with distal tracheoesophageal fistula. Uppersegment of esophagus ends in blind pouch and lower segment communicateswith trachea.Maternal history of polyhydramniosis common.Drooling, choking, and regurgitationoccur with first feeding.Opaque nasal catheter that fails topass into stomach and remains curled up in proximal esophagus establishesdiagnosis. Air in stomach on chest radiograph indicates presenceof tracheoesophageal fistula. If diagnosis is uncertain, injectionof small amount of contrast material into upper esophagus with fluoroscopyis confirmatory. Esophageal Stenosis
Usuallyoccurs in middle third of esophagus.Regurgitation and poor weight gainare prominent symptoms.Contrast esophagram is diagnostic. Esophageal Web
Mucosalmembrane that usually occurs in upper esophagus or at junction between middleand lower third of esophagus.Obstruction may be complete and causeregurgitation soon after birth.Diagnosis may be confirmed by esophagramor endoscopy. Duplication
Duplicationsof esophagus are cystic or tubular structures that can compressesophagus, causing regurgitation. Some duplications contain gastricmucosa, which may produce GI bleeding.Combination of tests, including chestradiography, upper GI radiographic series, and chest CT or MRI,is diagnostic. Foreign Body
Esophagealforeign bodies usually cause obstruction at level of cricopharyngeusmuscle or just above lower esophageal sphincter.Choking, coughing, dysphagia, regurgitation,and vomiting may occur. If foreign body is radiopaque, it may beseen on chest radiograph. Otherwise, filling defect is usually seenon esophagram.Diagnosis may be confirmed by endoscopy. Stricture
Usuallydue to long-standing reflux esophagitis but also may be due to causticingestion.Usual manifestations are dysphagia,regurgitation, and vomiting.Contrast esophagraphy or endoscopyis diagnostic. Hiatal Hernia
Herniationof portion of stomach into thorax.Usually is congenital and often isassociated with gastroesophageal reflux.Although regurgitation, vomiting, andepigastric pain may occur, it can be asymptomatic.Upper GI radiographic series is diagnostic. Rumination
Regurgitationof already ingested food from stomach and esophagus into mouth, whereit is rechewed and swallowed or spit out.Primarily occurs in 2 populations:developmentally impaired young children as self-stimulation behaviorand adolescents with significant psychological stress. Younger childrenhave minimal vomiting, whereas adolescents have significant vomiting.pH probe shows resolution of esophagealacidification during sleep. Diagnostic Approach: Regurgitation
In infantwith regurgitation who is otherwise well and gaining weight, mostlikely diagnosis is normal variation or mild gastroesophageal reflux.Persistent regurgitation with poorweight gain, respiratory symptoms, or symptoms suggesting esophagitisrequires investigation.Upper GI radiographic series excludesother causes of esophageal obstruction. Most reliable test for gastroesophagealreflux is esophageal pH monitoring. Endoscopy with biopsy can confirmdiagnosis of esophagitis.Other investigations depend on history,physical exam, and results of the above studies.
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Source: The Diagnostic Approach to Symptoms and Signs in Pediatrics, 2006
Vomiting:
History and physical examination
(Nursing: Interpreting Signs and Symptoms)
Ask your patient to describe the onset, duration, and intensity of his vomiting. What started the vomiting? What makes it subside? If possible, collect, measure, and inspect the character of the vomitus. (See Vomitus: Characteristics and causes.) Explore associated complaints, particularly nausea, abdominal pain, anorexia and weight loss, changes in bowel habits or stools, excessive belching or flatus, and bloating or fullness.
Obtain a medical history, noting GI, endocrine, and metabolic disorders; recent infections; and cancer, including chemotherapy or radiation therapy. Ask the patient about current medication use and alcohol consumption. If the patient is a female of childbearing age, ask if she is or could be pregnant or which contraceptive method she's using.
Inspect the patient's abdomen for distention and localized bulging, and auscultate for bowel sounds and bruits. Palpate for rigidity and tenderness and test for rebound tenderness. Palpate and percuss the liver for enlargement. Assess the patient's other body systems as appropriate.
During the examination, keep in mind that projectile vomiting unaccompanied by nausea may be an indication of increased intracranial pressure, a life-threatening emergency. If this occurs in a patient with CNS injury, you should quickly check his vital signs. Be alert for widened pulse pressure or bradycardia.
» READ BOOK EXCERPT ONLINE »
Source: Nursing: Interpreting Signs and Symptoms, 2007
NAUSEA AND VOMITING:
Approach to the Diagnosis
(Differential Diagnosis in Primary Care)
The association of other symptoms and signs is essential in pinpointing
the diagnosis of vomiting. For example, vomiting with tinnitus and vertigo
suggests Ménière disease, whereas vomiting with hematemesis suggests
gastritis, esophageal varices, and gastric ulcers. The laboratory workup
should include a flat plate of the abdomen, upper GI series, esophagram,
cholecystogram, gastric analysis, serum electrolytes, and amylase and lipase
levels. Stools for occult blood, ova, and parasites are usually indicated.
Gastroscopy and esophagoscopy are often indicated in the acute case, but an
exploratory laparotomy should not be delayed if the patient’s condition is
deteriorating and pancreatitis has been excluded.
» READ BOOK EXCERPT ONLINE »
Source: Differential Diagnosis in Primary Care, 2007
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