Diseases » Generalized pustular psoriasis » Introduction

Generalized pustular psoriasis

Generalized pustular psoriasis: Introduction

Generalized pustular psoriasis: This is a rare form of psoriasis is also known as von Zumbusch psoriasis. It can be life-threatening especially in the elderly. It is characterized by the development of pustules in the flexural areas - the backs of the knees, the insides of the elbows, the armpits and the groin. These pustules continue to spread and soon they join to form lakes of pus. The pustules rupture easily and can become infected. This condition can be fatal if the patient gets dehydrated, or the infection spreads to the bloodstream. Generalized pustular psoriasis is often triggered by stopping topical or oral steroids. More detailed information about the symptoms, causes, and treatments of Generalized pustular psoriasis is available below.

Symptoms of Generalized pustular psoriasis

• Raised pus-filled skin bumps
• Skin redness around pustules
• Stinging skin
• Itching skin
• Burning skin
• more symptoms...»

See full list of 24 symptoms of Generalized pustular psoriasis

Generalized pustular psoriasis: Complications

Review possible medical complications related to Generalized pustular psoriasis:

• Death
• Secondary bacterial infection
• Disturbed protein and electrolyte balance, especially low albumin and calcium
• Renal and liver impairment
• Malabsorption of nutrients and therapeutic drugs
• more complications...»

Wrongly Diagnosed with Generalized pustular psoriasis?

• Failure to diagnose Generalized pustular psoriasis
• Hidden causes of Generalized pustular psoriasis (possibly wrongly diagnosed)
• Undiagnosed: Generalized pustular psoriasis

Causes of Generalized pustular psoriasis

• Sudden withdrawal of injected or oral corticosteroids
• Drugs such as lithium, salicylates, indomethacin, iodide and some beta-blockers
• Strong, irritating topical preparations such as coal tar, dithranol and strong topical corticosteroids under occlusion
• Infection
• Pregnancy
• more causes...»

Read more about causes of Generalized pustular psoriasis

More information about causes of Generalized pustular psoriasis:

• Underlying causes of Generalized pustular psoriasis
• Generalized pustular psoriasis as a complication caused by other conditions

Treatments for Generalized pustular psoriasis

• Rehydration, antibiotics, topical treatments, other medications such as soriatane, cyclosporine, methotrexate
• Oral retinoid such as acitretin, derived from vitamin A
• Sometimes it is necessary to restart corticosteroids, usually temporarily
• Other medications such as methotrexate, colchicine, ciclosporin, tioguanine and hydroxyurea have been used with some success
• Phototherapy (ultraviolet radiation), especially in combination with oral psoralens (PUVA). This is usually started once the patient has been stabilised on acitretin
• more treatments...»

Read more about treatments for Generalized pustular psoriasis

Evidence Based Medicine Research for Generalized pustular psoriasis

Medical research articles related to Generalized pustular psoriasis include:

• Pustular Psoriasis
• Psoriasis, Pustular (Follow-up)
• Psoriasis, Pustular (Diagnosis)
• Psoriasis, Pustular (Overview)
• Psoriasis, Pustular (Treatment)
• Rigors
• more research...»

Click here to find more evidence-based articles on the TRIP Database

Prognosis for Generalized pustular psoriasis

Prognosis for Generalized pustular psoriasis: Death can result from cardiorespiratory failure during the acute eruptive phase so it is very important to treat as early as possible.

More about prognosis of Generalized pustular psoriasis

Reseach about Generalized pustular psoriasis

Visit our research pages for current research about Generalized pustular psoriasis treatments.

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