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Diseases » Glanders » Treatments
 

Treatments for Glanders

Treatments for Glanders

The list of treatments mentioned in various sources for Glanders includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

Hospital statistics for Glanders:

These medical statistics relate to hospitals, hospitalization and Glanders:

  • 0% (5) of hospital consultant episodes were for glanders and meliodosis in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 100% of hospital consultant episodes for glanders and meliodosis required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 60% of hospital consultant episodes for glanders and meliodosis were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 40% of hospital consultant episodes for glanders and meliodosis were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 60% of hospital consultant episodes for glanders and meliodosis required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • more hospital information...»

Discussion of treatments for Glanders:

Because human cases of glanders are rare, there is limited information about antibiotic treatment of the organism in humans. Sulfadiazine has been found to be an effective in experimental animals and in humans. Burkholderia mallei is usually sensitive to tetracyclines, ciprofloxacin, streptomycin, novobiocin, gentamicin, imipenem, ceftrazidime, and the sulfonamides. Resistance to chloramphenicol has been reported. (Source: excerpt from Glanders General: DBMD)

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Book Excerpts: Treatment of Glanders

Treatments of Glanders: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the treatments of Glanders.

Pseudomonas infections: Treatment
(Professional Guide to Diseases (Eighth Edition))

In the debilitated or otherwise vulnerable patient with clinical evidence of Pseudo-monas infection, treatment should begin immediately, without waiting for results of laboratory tests. Antibiotic treatment includes aminoglycosides, such as gentamicin or tobramycin, combined with an antipseudomonal penicillin, such as ticarcillin or piperacillin. An alternative combination is amikacin and a similar penicillin or imipenem and cilastatin. Such combination therapy is necessary because Pseudomonas quickly becomes resistant to ticarcillin alone.

Local Pseudomonas infections or septicemia secondary to wound infection requires 1% acetic acid irrigations; topical applications of colistimethate, polymyxin B, and silver sulfadiazine cream; and debridement or drainage of the infected wound.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Pseudomonas infections: Treatment
(Handbook of Diseases)

In the debilitated or otherwise vulnerable patient with clinical evidence of Pseudomonas infection, treatment should begin immediately, even before  the results of laboratory tests are received.

Antibiotic treatment includes aminoglycosides, such as gentamicin or tobramycin, combined with a Pseudo-monas-sensitive penicillin, such as carbenicillin disodium or ticarcillin. An alternative combination is amikacin and a similar penicillin. Such combination therapy is necessary because Pseu-domonas quickly becomes resistant to carbenicillin alone.

CLINICAL TIP: In bacteremia, an aminoglycoside and beta-lactam antibiotic with anti-Pseudo-monals activity increases survival rates.

In urinary tract infections, carbenicillin indanyl sodium can be used alone if the organism is susceptible and the infection doesn’t have systemic effects; it’s excreted in the urine and builds up high urine levels that prevent resistance.

Local Pseudomonas infections or septicemia secondary to wound infection require 1% acetic acid irrigations, topical application of colistimethate sodium and polymyxin B, and debridement or drainage of the infected wound.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003



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