What is Guillain-Barre Syndrome?
What is Guillain-Barre Syndrome?
- Guillain-Barre Syndrome: Rare autoimmune disorder destroying nerve function lead to weakness and paralysis.
- Guillain-Barre Syndrome: progressive ascending motor neuron paralysis of unknown etiology, frequently following an enteric or respiratory infection.
Source - Diseases Database
- Guillain-Barre Syndrome: a form of peripheral polyneuritis characterized by pain and weakness and sometimes paralysis of the limbs; cause is unknown.
Source - WordNet 2.1
Guillain-Barre Syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Guillain-Barre Syndrome, or a subtype of Guillain-Barre Syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Guillain-Barre Syndrome as a "rare disease".
Source - Orphanet
Guillain-Barre Syndrome: Introduction
Types of Guillain-Barre Syndrome:
Types of Guillain-Barre Syndrome:
Broader types of Guillain-Barre Syndrome:
How many people get Guillain-Barre Syndrome?
Prevalance of Guillain-Barre Syndrome: about 1 in 100,000 (NWHIC)
Prevalance Rate of Guillain-Barre Syndrome: approx 1 in 100,000 or 0.00% or 2,720 people in USA [about data]
Incidence (annual) of Guillain-Barre Syndrome: about 1 in 100,000 (NWHIC)
Incidence Rate of Guillain-Barre Syndrome: approx 1 in 100,000 or 0.00% or 2,720 people in USA [about data]
Prevalance of Guillain-Barre Syndrome:
Guillain Barre Syndrome (GBS) is a rare disorder, afflicting about 1
person in 100,000. (Source: excerpt from NIAID Guillain Barre Fact Sheet: NIAID)
Incidence of Guillain-Barre Syndrome: The syndrome is rare,
however, afflicting only about one person in 100,000. (Source: excerpt from Guillain-Barre Syndrome: NWHIC)
Who gets Guillain-Barre Syndrome?
Profile for Guillain-Barre Syndrome: affects both sexes of any age. (Source: excerpt from NIAID Guillain Barre Fact Sheet: NIAID)
...
Guillain-Barre syndrome can affect anybody. It can strike at any age
and both sexes are equally prone to the disorder. (Source: excerpt from Guillain-Barre Syndrome: NWHIC)
Gender Profile for Guillain-Barre Syndrome: Equally men and women.
Geography Profile for Guillain-Barre Syndrome: It is
more common in Japan and China than in North America or Europe (Source: excerpt from NIAID Guillain Barre Fact Sheet: NIAID)
How serious is Guillain-Barre Syndrome?
Prognosis of Guillain-Barre Syndrome: Recovery within weeks for many. 30% still have weakness in 3 years. 3% have a relapse. Mortality rate around 3-4%.
Complications of Guillain-Barre Syndrome:
see complications of Guillain-Barre Syndrome
Prognosis of Guillain-Barre Syndrome:
Guillain-Barré syndrome can be a devastating disorder
because of its sudden and unexpected onset. Most people reach the stage of
greatest weakness within the first 2 weeks after symptoms appear, and by
the third week of the illness 90 percent of all patients are at their
weakest. The recovery period may be as little as a few weeks or as long as
a few years. About 30 percent of those with Guillain-Barré still have a
residual weakness after 3 years. About 3 percent may suffer a relapse of
muscle weakness and tingling sensations many years after the initial
attack.
(Source: excerpt from NINDS Guillain-Barre Syndrome Information Page: NINDS)
...
Most
patients, however, recover from even the most severe cases of
Guillain-Barre syndrome, although some continue to have minor problems.
(Source: excerpt from Guillain-Barre Syndrome: NWHIC)
What causes Guillain-Barre Syndrome?
Causes of Guillain-Barre Syndrome: see causes of Guillain-Barre Syndrome
Causes of Guillain-Barre Syndrome:
Usually Guillain-Barré occurs a few days
or weeks after the patient has had symptoms of a respiratory or
gastrointestinal viral infection. Occasionally, surgery or vaccinations
will trigger the syndrome.
The disorder can develop over the course of
hours or days, or it may take up to 3 to 4 weeks.
(Source: excerpt from NINDS Guillain-Barre Syndrome Information Page: NINDS)
...
GBS can probably result following a number of bacterial and viral
infections. Campylobacter jejuni induced diarrheal disease is
most often recognized as the precedent infection. (Source: excerpt from NIAID Guillain Barre Fact Sheet: NIAID)
Risk factors for Guillain-Barre Syndrome:
see
risk factors for Guillain-Barre Syndrome
What are the symptoms of Guillain-Barre Syndrome?
Symptoms of Guillain-Barre Syndrome:
see symptoms of Guillain-Barre Syndrome
Complications of Guillain-Barre Syndrome:
see complications of Guillain-Barre Syndrome
Incubation period for Guillain-Barre Syndrome: 1 to 3 weeks after an infection or other event.
Incubation period for Guillain-Barre Syndrome: The disorder can develop over the course of hours or days, or it
may take up to 3 to 4 weeks. (Source: excerpt from Guillain-Barre Syndrome: NWHIC)
Duration of Guillain-Barre Syndrome: usually a few weeks
Can anyone else get Guillain-Barre Syndrome?
Contagion of autoimmunity:
generally not; see details in contagion of autoimmune diseases.
Inheritance:
see inheritance of Guillain-Barre Syndrome
Guillain-Barre Syndrome: Testing
Diagnostic testing: see tests for Guillain-Barre Syndrome.
Misdiagnosis: see misdiagnosis and Guillain-Barre Syndrome.
How is it treated?
Treatments for Guillain-Barre Syndrome:
see treatments for Guillain-Barre Syndrome
Prevention of Guillain-Barre Syndrome:
see prevention of Guillain-Barre Syndrome
Research for Guillain-Barre Syndrome:
see research for Guillain-Barre Syndrome
Society issues for Guillain-Barre Syndrome
Costs of Guillain-Barre Syndrome: $247 million to $1.8 billion for Campylobacter induced GBS (NIAID)
Costs of Guillain-Barre Syndrome: The medical costs associated with Campylobacter induced GBS
has been estimated by the USDA to be between $57 and $425 million per
year in the U.S. Total costs, which include days of lost productivity,
are estimated to be between $247 million and $1.8 billion per year. (Source: excerpt from NIAID Guillain Barre Fact Sheet: NIAID)
Organs Affected by Guillain-Barre Syndrome:
Organs and body systems related to Guillain-Barre Syndrome include:
Name and Aliases of Guillain-Barre Syndrome
Main name of condition: Guillain-Barre Syndrome
Class of Condition for Guillain-Barre Syndrome: autoimmune
Other names or spellings for Guillain-Barre Syndrome:
Guillain-Barré Syndrome, GBS, acute polyneuritis, ascending paralysis, acute infective polyneuritis, Acute inflammatory demyelinating polyneuropathy, Landry-Guillain-Barre syndrome, Acute inflammatory polyneuropathy
Guillain-Barre syndrome, Infectious polyneuritis, Landry's paralysis
Source - WordNet 2.1
Acute inflammatory demyelinating polyneuropathy, Acute inflammatory polyneuropathy, GBS, Landry-Guillain-Barre syndrome
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)
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