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Consider the broad-differential diagnosis for respiratory distress in children

Consider the broad-differential diagnosis for respiratory distress in children: Excerpt from Avoiding Common Pediatric Errors

Author: Sarika Joshi, MD

What to Do - Gather Appropriate Data

It is important for pediatricians to recognize the signs and symptoms of respiratory distress, as it is a common presenting complaint for children. With a careful history and physical exam, it is possible to narrow down the broad differential for respiratory distress so that appropriate treatment may be started. Respiratory distress is characterized by increased work of breathing (i.e., tachypnea, flaring, retractions) often in association with pulmonary exam findings such as stridor, wheezing, and rales.

Important elements of the history for a child with respiratory distress include trauma, voice changes (i.e., muffled, hoarse), and associated symptoms, such as fever. Prior episodes of respiratory distress or any chronic medical conditions are also significant parts of the history. Physical exam should start with vital signs, especially respiratory rate and oxygen saturation. The World Health Organization defines tachypnea (in breaths per minute) based on age: >60 for age <2 months, >50 for ages 2 months to 1 year, >40 for ages 1 to 5 years, >20 for age >5 years. Remember that for febrile children, each degree Celsius increase may cause an increase of up to 10 breaths per minute. In additionto the respiratory rate,pay attention tothe respiratory pattern. For instance, Kussmaul breathing and Cheyne-Stokes breathing occur with metabolic acidosis and central nervous system (CNS) processes, respectively.

Prior to auscultation, careful observation of the child in respiratory distress may provide important clues to the diagnosis. Mental status changes, such as combativeness or somnolence, may indicate severe hypoxia or hypercarbia. Cyanosis is a late sign in the hypoxic child. The child will assume a position that decreases work of breathing. For example, a child with upper airway obstruction may assume the "sniffing position." Observe whether there is nasal flaring, head bobbing, retractions (supraclavicular, intercostal, substernal), or grunting, all of which signify respiratory distress. If there is cough, listen to the quality: hoarse or barky (suggests upper airway problem), tight and persistent (suggests lower airway obstruction), or loose and productive (suggests infection). On auscultation, particularly note stridor, wheezing, rales,anddecreasedbreathsounds.Stridor is generally aninspiratory noise from upper airway obstruction. Wheezing is usually an expiratory noise from lower airway obstruction. Rales are typically an inspiratory noise from lower airway reinflation, which occurs in pneumonia and pulmonary edema. Decreased breath sounds may indicate local areas of collapse, consolidation, or fluid.

Armed with your history and physical exam findings, it is then conceptually helpful to categorize the child with respiratory distress as follows: (a) upper airway obstruction; (b) asymmetric breath sounds, no upper airway obstruction;(c)symmetricbreathsounds,noupperairwayobstruction.Childrenwithupperairwayobstructionwillhavesymptomssuchasstridor,voice changes, and dysphagia. Some causes of afebrile upper airway obstruction in children are foreign body, neck trauma, and upper airway burns. Causes of febrile upperairway obstruction includecroup,retropharyngeal abscess, and epiglottitis. Asymmetric breath sounds indicate a focal pulmonary process. An important cause of afebrile asymmetric breath sounds, often with a history of trauma, is pneumothorax. Atelectasis can produce this picture, with or without fever. Lobar pneumonia is a cause of febrile asymmetric breath sounds, typically associated with rales. Symmetric breath sounds suggest a diffusepulmonaryprocessoranonpulmonaryprocess.Pulmonaryprocesses that present in this manner include viral or atypical pneumonia (usually with fever and rales), asthma (generally with wheezing), and bronchiolitis (typically with fever, rales, and wheezing). Significant nonpulmonary etiologies to consider are myocarditis, metabolic acidosis, and CNS processes.

In summary, the differential diagnosis of respiratory distress in children is broad and necessitates a careful history and physical exam. Important features include recognition of the signs of increased work of breathing and auscultation of symptoms such as stridor, rales, wheezing, and differential breath sounds.

Suggested Readings

Margolis P, Gadomski A. The rational clinical examination. Does this infant have pneumonia? JAMA. 1998;279:308–313.
Zaritsky AL, Nadkarni VM, Hickey RW, et al., eds. Pediatric Advanced Life Support Provider Manual. Dallas, TX: American Heart Association; 2002.

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Book Source Details

  • Book Title: Avoiding Common Pediatric Errors
  • Author(s): Anthony D Slonim MD, DrPH; Lisa Marcucci MD
  • Year of Publication: 2008
  • Copyright Details: Avoiding Common Pediatric Errors, Copyright © 2008 Lippincott Williams & Wilkins.

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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.




More About This Book:
Title: Avoiding Common Pediatric Errors
Authors: Anthony D Slonim MD, DrPH; Lisa Marcucci MD
Publisher: Lippincott Williams & Wilkins
Copyright: 2008
ISBN: 0-7817-7489-6

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