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Serum Thyroid-Stimulating Hormone

Serum Thyroid-Stimulating Hormone: Excerpt from A Pocket Manual of Differential Diagnosis

Elevated Serum Thyroid-Stimulating Hormone


Primary hypothyroidism
Overt (low free T4)
Subclinical (normal free T4)
Assay problems
   Assay variability
   Heterophile antibodies interfering with the TSH assay
Drugs
   Domperidone
   Metoclopramide
Pulsatile TSH secretion, nocturnal TSH surge
Recovery from nonthyroidal illness
Thyroid hormone resistance syndromes
TSH-secreting pituitary tumors

Suppressed Serum Thyroid-Stimulating Hormone


Thyrotoxicosis
Overt (low free T4)
Subclinical (normal free T4)
T3 Toxicosis (with normal or low free T4)
After treatment of thyrotoxicosis, before the axis recovers from suppression
Drugs
   Dopamine
   Glucocorticoids
Laboratory error
Secondary (pituitary) and tertiary (hypothalamic) hypothyroidism
Severe nonthyroidal illness

References


1. Ross DS: Subclinical Hypothyroidism, pp. 1010–1011. See Bibliography, 4.
2. Ross DS: Subclinical Thyrotoxicosis, pp. 1016–1017. See Bibliography, 4.

Book Source Details

  • Book Title: A Pocket Manual of Differential Diagnosis
  • Author(s): Stephen N. Adler, Dianne B. Gasbarra
  • Year of Publication: 1999
  • Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 1999 Lippincott Williams & Wilkins.

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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.




More About This Book:
Title: A Pocket Manual of Differential Diagnosis
Authors: Stephen N. Adler, Dianne B. Gasbarra
Publisher: Lippincott Williams & Wilkins
Copyright: 1999
ISBN: 0-78171-943-7

 » Next page: Goiter/Neck Mass (A Pocket Manual of Differential Diagnosis)

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