TREATMENTS &
RESEARCH

Search the
latest
treatment
information
here.

Dr. Huntley's
Diagnosis
Checklist

Have a symptom?
See what questions
a doctor would ask.

Diseases » Heartburn » Clinical Trials

Clinical Trials for Heartburn

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Heartburn is grouped into the following categories:-

View by trial name

View by drugs used in Heartburn clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Heartburn:

Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn - This study is currently recruiting patients (Current: 23 Nov 2006) - Lanzoprazole
Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn - This study is currently recruiting patients (Current: 23 Nov 2006) - Lansoprazole
A Study of the Safety of Rabeprazole Administered to Adults With Gastroesophageal Reflux Disease (GERD) - This study is no longer recruiting patients (Current: 23 Nov 2006) - rabeprazole sodium
A Study of Efficacy and Safety of "on-Demand" Maintenance Therapy With Rabeprazole in Patients With Non-Erosive Reflux Disease (NERD) - This study is no longer recruiting patients (Current: 23 Nov 2006) - rabeprazole
Safety and Efficacy Study of Axid Use in Infants Suffering From GERD - This study is currently recruiting patients (Current: 23 Nov 2006) - nizatidine (Axid)
The Effects of Tegaserod on Mechanical Sensitivity of the Esophagus and Stomach in Patients With Heartburn and Dyspepsia. - This study is currently recruiting patients (Current: 23 Nov 2006) - Tegaserod
Acid-Associated Heartburn Symptoms and Dose of Esomeprazole - This study is no longer recruiting patients (Current: 23 Nov 2006) - Esomeprazole magnesium
E3810-A001-313: Efficacy and Safety of 10 Mg Rabeprazole for Treating Heartburn in Frequent Sufferers - This study is no longer recruiting patients (Current: 23 Nov 2006) - Rabeprazole sodium
E3810-A001-312: Efficacy and Safety of 10 Mg Rabeprazole for Treating Heartburn in Frequent Sufferers - This study is no longer recruiting patients (Current: 23 Nov 2006) - RABEPRAZOLE SODIUM
HEARD (Long Term) Study Histology of the Esophagus in Acid-Related Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Esomeprazole
Itopride in Heartburn - This study is currently recruiting patients (Current: 23 Nov 2006) - Itopride
A Study of Rabeprazole and Pantoprazole on Stomach Acid and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease (GERD) and a History of Nighttime Heartburn - This study is no longer recruiting patients (Current: 23 Nov 2006) - rabeprazole and pantoprazole
Assessment of the Role of Tegaserod Therapy in the Management of Gastroesophageal Reflux Disease (GERD) Symptoms in Patients With Incomplete Response to Proton Pump Inhibitors (PPIs). - This study has been completed (Current: 23 Nov 2006) - Tegaserod
A Study to Compare the Efficacy and Safety of TAK390MR and Placebo in Treating the Symptoms of Gastroesophageal Reflux Disease (GERD). - This study is no longer recruiting patients (Current: 23 Nov 2006) - TAK-390MR Oral
Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
Efficiency Study of S-Tenatoprazole-Na to Treat Erosive or Ulcerative Esophagitis. - This study has been suspended (Current: 23 Nov 2006) - S-Tenatoprazole-Na (STU-Na)
PPI Test in GP Patients - This study is no longer recruiting patients (Current: 23 Nov 2006) - Esomeprazole
Safety and Efficacy Study of TAK-390MR to Treat Heartburn - This study is currently recruiting patients (Current: 23 Nov 2006) - TAK-390 MR 30 mg oral,TAK-390MR 60 mg oral
PPI Sequencing Study - This study is currently recruiting patients (Current: 23 Nov 2006) - Esomeprazole
Symptom Improvements in GERD Patients - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - AZD3355
PPI Versus Placebo in Severe Functional Heartburn - This study is currently recruiting patients (Current: 23 Nov 2006) - PPI
Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life - This study is currently recruiting patients (Current: 23 Nov 2006)
A Study to Compare the Efficacy and Safety of TAK390MR and Placebo in Treating the Symptoms of Gastroesophageal Reflux Disease (GERD) - This study is no longer recruiting patients (Current: 23 Nov 2006) - TAK-390MR
A Study to Assess the Efficacy, Safety and Tolerability of Tegaserod Alone and in Combination With Omeprazole Given Orally in Patients With Symptoms of Symptomatic Gastroesophageal Reflux Disease (sGERD) - This study has been completed (Current: 23 Nov 2006) - Tegaserod

Drugs used in Clinical Trials for Heartburn

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Heartburn: