20,000 people in the United States (NHLBI) ... see also overview of Hemophilia.
approx 1 in 13,600 or 0.01% or 20,000 people in USA [Source statistic for calcuation: "20,000 people in the United States (NHLBI)" -- see also general information about data sources]
Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Hemophilia as a "rare disease". More information about Hemophilia is available from Orphanet
about 400 babies annually (NHLBI) ... see also overview of Hemophilia.
approx 1 in 680,000 or 0.00% or 400 people in USA [Source statistic for calcuation: "about 400 babies annually (NHLBI)" -- see also general information about data sources]
399 per year, 33 per month, 7 per week, 1 per day, 0 per hour, 0 per minute, 0 per second. [Source statistic for calculation: "about 400 babies annually (NHLBI)" -- see also general information about data sources]
There are about 20,000 hemophilia patients in the United States. (Source: excerpt from Hemophilia: NHLBI)
Each year, about 400 babies are born with this disorder. (Source: excerpt from Hemophilia: NHLBI)
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Hemophilia.
Both hemophilia A and B are inherited as X-linked recessive traits. This means that female carriers have a 50% chance of transmitting the gene to each daughter, who would then be a carrier, and a 50% chance of transmitting the gene to each son, who would be born with hemophilia. Hemophilia A (classic hemophilia), which affects more than 80% of patients with hemophilia, results from a deficiency of factor VIII-C; hemophilia B (Christmas disease), which affects approximately 15% of patients with hemophilia, results from a deficiency of factor IX-C.
The factor VIII gene is located within the Xq28 region, and the factor IX gene is located within Xq27. Females with one defective factor VIII gene are carriers of hemophilia. A large number of disease-causing mutations have been identified in both genes. A specific inversion mutation in the noncoding region of the factor VIII gene is present in approximately 45% of families with severe hemophilia A. Hemophilia A is the most common X-linked genetic disease, occurring in approximately 1 in 10,000 live male births. It is five times more common than hemophilia B.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Source: The 5-Minute Pediatric Consult, 2008
The term 'prevalence' of Hemophilia usually refers to the estimated population of people who are managing Hemophilia at any given time. The term 'incidence' of Hemophilia refers to the annual diagnosis rate, or the number of new cases of Hemophilia diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.
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