Hereditary spastic paralysis, infantile onset ascending: A rare inherited progressive condition where the muscles of the arms, legs and face become increasingly weak and stiff due to damage to nerve cells that control muscle movement. The legs are affected first and then the arms and face - the symptoms ascend up the body. This condition involves mutations in the same gene and overlapping symptoms with juvenile primary lateral sclerosis but the difference is that primary lateral sclerosis only involves degeneration of the upper motor neurons whereas infantile-onset spastic paralysis is more severe and involves degeneration of upper and lower motor neurons. More detailed information about the symptoms, causes, and treatments of Hereditary spastic paralysis, infantile onset ascending is available below.
See full list of 9 symptoms of Hereditary spastic paralysis, infantile onset ascending
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Prognosis for Hereditary spastic paralysis, infantile onset ascending: usually wheelchair bound by late childhood or early adolescence
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Hereditary spastic paralysis, infantile onset ascending is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Hereditary spastic paralysis, infantile onset ascending, or a subtype of Hereditary spastic paralysis, infantile onset ascending,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
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