HIV-1, CRF04_ cpx: HIV is an immune system disease caused by the HIV virus. AIDS is a term used when a person infected with HIV has a CD4+ T cell count below 200 or 14% of lymphocytes. AIDS is an advanced form of HIV. To be classified as AIDS the person must also have an AIDS-related condition such as opportunistic infections. Once a person has been diagnosed with AIDS, even if treatment improved their CD4+ T cell count and infections are under control, the person is still considered to have AIDS. HIV is classified into two subtypes - HIV-1 and HIV-2. HIV-1 is further classified into three groups - Group M, N and O. Group M is further classified into 9 subgroups - A to K and CRFs. CRF's are circulating recombinant forms which are a combination of any two subtypes e.g. CRF A/B involves both And B subtypes. HIV-1, Group M, subtype CRF_cpx is made up of a combination of subtypes A, G, H, K, and U - (cpx refers to a complex of two or more subtypes). This subtype has been diagnosed in Cyprus and Greece. More detailed information about the symptoms, causes, and treatments of HIV-1, CRF04_ cpx is available below.
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Prognosis for HIV-1, CRF04_ cpx: Death usually occurs between 6 and 19 months after diagnosis of AIDS if not treatment is utilized. Strict adherence to treatment plans (usually antiretroviral medications) can significantly improve long-term outcomes. A number of people will develop a resistance to treatment therapies if they have been on them for more than two decades.
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