Diagnosis of Hodgkin's Disease
Diagnostic Test list for Hodgkin's Disease:
The list of medical tests
mentioned in various sources as
used in the diagnosis of Hodgkin's Disease
includes:
Hodgkin's Disease Diagnosis: Book Excerpts
Tests and diagnosis discussion for Hodgkin's Disease:
If Hodgkin's disease is suspected, the doctor asks about
the person's medical history and performs a physical exam to
check general signs of health. The exam includes feeling to
see if the lymph nodes in the neck, underarm, or groin are
enlarged. The doctor may order blood tests.
The doctor may also order tests that produce pictures of
the inside of the body. These may include:
-
X-rays :
High-energy radiation used to take pictures of areas inside
the body, such as the chest, bones, liver, and spleen.
-
CT
(or CAT) scan : A series of detailed pictures
of areas inside the body. The pictures are created by a
computer linked to an x-ray machine.
-
MRI
(magnetic resonance imaging): Detailed
pictures of areas inside the body produced with a powerful
magnet linked to a computer.
The diagnosis depends on a biopsy .
A surgeon removes a sample of lymphatic tissue (part or all of
a lymph node) so that a pathologist
can examine it under a microscope to check for cancer cells.
Other tissues may be sampled as well. The pathologist studies
the tissue and checks for Reed-Sternberg
cells , large abnormal cells that are usually found
with Hodgkin's disease. (Source: excerpt from What You Need To Know About Hodgkin's Disease: NCI)
Diagnosis of Hodgkin's Disease: medical news summaries:
The following medical news items
are relevant to diagnosis and misdiagnosis issues for Hodgkin's Disease:
Diagnostic Tests for Hodgkin's Disease: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about diagnostis of Hodgkin's Disease.
Hodgkin's disease:
Diagnosis
(Professional Guide to Diseases (Eighth Edition))
Diagnostic measures for confirming Hodgkin's disease include a thorough medical history and a complete physical examination, followed by a lymph node biopsy checking for Reed-Sternberg's abnormal histiocyte proliferation and nodular fibrosis and necrosis. (See Reed-Sternberg cells.)
Other appropriate diagnostic tests include bone marrow, liver, mediastinal, lymph node, and spleen biopsies and routine chest X-ray, abdominal computed tomography scan, positron emission tomography, lung scan, bone scan, and lymphangiography to detect lymph node or organ involvement. Laparoscopy and lymph node biopsy are performed to complete staging.
Hematologic tests show mild to severe normocytic anemia; normochromic anemia (in 50%); elevated, normal, or reduced white blood cell count and differential showing any combination of neutrophilia, lymphocytopenia, monocytosis, and eosinophilia. Elevated serum alkaline phosphatase indicates liver or bone involvement.
The same diagnostic tests are also used for staging. A staging laparotomy is necessary for patients younger than age 55 or without obvious stage III or stage IV disease, lymphocyte predominance subtype histology, or medical contraindications. Diagnosis must rule out other disorders that also enlarge the lymph nodes.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Non-Hodgkin's lymphoma:
Diagnosis
(Professional Guide to Diseases (Eighth Edition))
Diagnosis requires histologic evaluation of biopsied lymph nodes; of tonsils, bone marrow, liver, bowel, or skin; or of tissue removed during exploratory laparotomy. (Biopsy differentiates non-Hodgkin's lymphoma from Hodgkin's disease.) (See Classifying non-Hodgkin's lymphomas, page 142.)
Other tests include bone and chest X-rays, lymphangiography, liver and spleen scan, computed tomography scan of the abdomen and chest, positron emission tomography, and excretory urography. Laboratory tests include complete blood count (may show anemia), uric acid (elevated or normal), serum calcium (elevated if bone lesions are present), serum protein (normal), and liver function studies.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Lymphomas, malignant:
Diagnosis
(Handbook of Diseases)
A positive diagnosis requires histologic evaluation of biopsied lymph nodes of tonsils, bone marrow, liver, bowel, or skin or of tissue removed during exploratory laparotomy. A biopsy differentiates malignant lymphoma from Hodgkin’s disease.
Other tests include bone and chest X-rays, lymphangiography, a liver and spleen scan, computed tomography scan of the abdomen, and excretory urography. Laboratory tests include a complete blood cell count (which may show anemia), uric acid level (elevated or normal), serum calcium level (elevated if bone lesions are present), serum protein level (normal), and liver function studies.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Hodgkin's disease:
Diagnosis
(Handbook of Diseases)
Diagnostic measures for confirming Hodgkin’s disease include a thorough medical history and a complete physical examination, followed by a lymph node biopsy checking for abnormal histiocyte proliferation of Reed-Sternberg cells (a giant atypical tumor cell) and nodular fibrosis and necrosis.
Other appropriate diagnostic tests include bone marrow, liver, mediastinal, lymph node, and spleen biopsies; routine chest X-ray; abdominal computed tomography scan; lung scan; bone scan; and lymphangiography to detect lymph node or organ involvement. Laparoscopy and a lymph node biopsy are performed to complete staging.
Hematologic tests show mild to severe normocytic anemia, normochromic anemia (in 50% of patients), and an elevated, normal, or reduced white blood cell count and differential showing any combination of neutrophilia, lymphocytopenia, monocytosis, and eosinophilia. An elevated serum alkaline phosphatase level indicates liver or bone involvement.
The same diagnostic tests are also used for staging. A staging laparotomy is necessary for patients under age 55 and those without obvious stage III or stage IV disease, lymphocyte predominance subtype histology, or medical contraindications. Diagnosis must rule out other disorders that enlarge the lymph nodes. (See Staging Hodgkin’s disease.)
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Non Hodgkin Lymphoma:
Non Hodgkin Lymphoma - DIAGNOSIS
(The 5-Minute Pediatric Consult)
A diagnosis needs to be made expeditiously, as pediatric lymphomas generally have a rapid growth rate.
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
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