Holoprosencephaly

Holoprosencephaly: Introduction

Holoprosencephaly: Holoprosencephaly is a disorder caused by the failure of the prosencephalon (the forebrain of the embryo) to divide to form bilateral ... more about Holoprosencephaly.

Holoprosencephaly: A rare disorder where abnormalities of the fetal forebrain development lead to various birth defects. More detailed information about the symptoms, causes, and treatments of Holoprosencephaly is available below.

Symptoms of Holoprosencephaly

• Spontaneous intrauterine death
• Severe facial defects
  • Cyclopia
  • Ethmocephaly
  • Cebocephaly
• more symptoms...»

See full list of 20 symptoms of Holoprosencephaly

Home Diagnostic Testing

Home medical testing related to Holoprosencephaly:

• Brain & Neurological Disorders: Related Home Testing:
  • ADHD -- Home Tests
  • Drug Screening Kits
• more tests...»

Holoprosencephaly: Complications

Read more about complications of Holoprosencephaly.

Wrongly Diagnosed with Holoprosencephaly?

• Misdiagnosis of Holoprosencephaly
• Hidden causes of Holoprosencephaly (possibly wrongly diagnosed)

Holoprosencephaly: Self Assessment Tools

• Stroke -- Self Assessment Tools
• more tools...»

Holoprosencephaly: Marketplace Products, Discounts & Offers

Products, offers and promotion categories available for Holoprosencephaly:

• Stroke
• Brain
• more product offers...»

Holoprosencephaly: Undiagnosed Conditions

Commonly undiagnosed diseases in related medical categories:

• Brain & Neurological Disorders: Undiagnosed:
  • Adult ADHD -- Undiagnosed - ADHD can be undiagnosed in adults.
  • ADHD -- Undiagnosed
  • Alzheimer Disease -- Undiagnosed
  • Migraine -- Undiagnosed
  • Concentration Disorders -- Undiagnosed
  • Stroke -- Undiagnosed
  • Bipolar Disorder -- Undiagnosed
  • Schizophrenia -- Undiagnosed
  • Epilepsy -- Undiagnosed
• more undiagnosed conditions...»

Misdiagnosis and Holoprosencephaly

Undiagnosed stroke leads to misdiagnosed aphasia: BBC News UK reported on a man who had been institutionalized and treated for mental illness because he suffered from sudden inability to speak. This was initially...read more »

Dementia may be a drug interaction: A common scenario in aged care is for a patient to show mental decline to dementia. Whereas this can, of course, occur due to various medical conditions, such as a ...read more »

Mild traumatic brain injury often remains undiagnosed: Although the symptoms of severe brain injury are hard to miss, it is less clear for milder injuries, or even those causing a mild...read more »

MTBI misdiagnosed as balance problem: When a person has symptoms such as vertigo or dizziness, a diagnosis of brain injury may go overlooked. This is particularly true of mild traumatic brain injury (MTBI), for which...read more »

Brain pressure condition often misdiagnosed as dementia: A condition that results from an excessive pressure of CSF within the brain is often misdiagnosed. It may be misdiagnosed as Parkinson's...read more »

Post-concussive brain injury often misdiagnosed: A study found that soldiers who had suffered a concussive injury in battle often were misdiagnosed on their return. A variety of symptoms can occur in post...read more »

Children with migraine often misdiagnosed: A migraine often fails to be correctly diagnosed in pediatric patients. These patients are not the typical migraine sufferers, but migraines can also occur in children. See ...read more »

Read more about Misdiagnosis and Holoprosencephaly

Holoprosencephaly: Research Doctors & Specialists

Research related physicians and medical specialists:

• Neurology (Brain/CNS Specialists):
  • Neurology (Brain/CNS Specialists)
  • Pediatric Neurology (Child Brain Specialist)
  • Pediatric Neurosurgery (Child Neurosurgeon)
  • Clinical Neurophysiology
  • Neurodevelopment Disabilities
  • Neurosurgery (Brain Surgery)
  • Neuromusculoskeletal Medicine (Nerve/Muscle/Bone Specialists)
  • Neuroradiology
  • Vascular Neurology
  • Neuropathology
  • Otology / Neurotology (Ear/Hearing Specialists)
• Stroke & Vascular Specialists:
  • Vascular Neurology (Brain Blood Vessels)
  • Vascular & Interventional Radiology
  • Vascular Surgery (Blood Vessel Surgeon)
  • Neuropathology (Brain Diagnostics)
• Senior Health Specialists (Geriatrics):
  • Geriatric Medicine (Senior Health Specialist)
  • Geriatric Psychiatry (Senior Mental Health)
• more specialists...»

Other doctor, physician and specialist research services:

• Rate Your Doctor Online
• Research Your Doctor Online
• Review Patient Surveys About Your Doctor
• Research local specialists including ratings, affiliations, and sanctions.

Holoprosencephaly: Rare Types

Rare types of diseases and disorders in related medical categories:

• Brain & Neurological Disorders: Rare Types:
  • Adult ADHD -- Rare Types
  • ADHD -- Rare Types
  • Alzheimer Disease -- Rare Types
  • Migraine -- Rare Types
  • Concentration Disorders -- Rare Types
  • Stroke -- Rare Types
  • Bipolar Disorder -- Rare Types
  • Schizophrenia -- Rare Types
  • Epilepsy -- Rare Types
• more rare diseases...»

Causes of Holoprosencephaly

• Steinfeld syndrome
• Smith-Lemli-Opitz syndrome
• Kallmann syndrome
• Pallister-Hall syndrome
• Rubinstein-Taybi syndrome
• more causes...»

See full list of 6 causes of Holoprosencephaly

Read more about causes of Holoprosencephaly.

More information about causes of Holoprosencephaly:

• Holoprosencephaly as a symptom

Treatments for Holoprosencephaly

• Symptomatic and supportive
• more treatments...»

Read more about treatments for Holoprosencephaly

News Archives for Holoprosencephaly

Medical news articles related to Holoprosencephaly include:

• Scientists From 25 Countries Sequence Cow Genome
• Alzheimer's Plaques More Complex Than Thought
• Researchers Publish Genome Sequence for Duck-Billed Platypus
• Drug-Coated Stents Better Than Bare-Metal Ones in Complex Cases
• Primitive Plants Have Complex Sex Life
• more health news...»

Source: HealthDay News

Videos for Holoprosencephaly

Patient Surveys for Holoprosencephaly

• Patient Profile Survey
  Take Survey  View Results
• Survey about the symptoms of your Holoprosencephaly
  Take Survey  View Results

Prognosis for Holoprosencephaly

Prognosis for Holoprosencephaly: The prognosis for individuals with the disorder is poor. Most of those who survive show no significant developmental gains. (Source: excerpt from NINDS Holoprosencephaly Information Page: NINDS)

More about prognosis of Holoprosencephaly

Reseach about Holoprosencephaly

Visit our research pages for current research about Holoprosencephaly treatments.

Clinical Trials for Holoprosencephaly

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Holoprosencephaly include:

• Clinical and Genetic Studies on Holoprosencephaly - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of the Experiences and Needs of Parents Continuing a Pregnancy Following a Prenatal Diagnosis of Holopresencephaly - This study has been completed (Current: 23 Nov 2006)
• Genetic Analysis of Left-Right Axis Formations - This study is currently recruiting patients (Current: 23 Nov 2006)
• Genetic Analysis of Brain Disorders - This study is currently recruiting patients (Current: 23 Nov 2006)
• more trials...»

Read more about Clinical Trials for Holoprosencephaly

Statistics for Holoprosencephaly

• Medical statistics for Holoprosencephaly
• Prevalence and incidence statistics for Holoprosencephaly
• Death and Mortality statistics for Holoprosencephaly
• Society statistics for Holoprosencephaly

Holoprosencephaly: Broader Related Topics

• Congenital conditions
• Brain conditions
• more types...»

Types of Holoprosencephaly

Types of Holoprosencephaly

• Alobar Holoprosencephaly
• Semilobar Holoprosencephaly
• Lobar Holoprosencephaly
• more types...»

Read more about Types of Holoprosencephaly

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User Interactive Forums

Read about other experiences, ask a question about Holoprosencephaly, or answer someone else's question, on our message boards:

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Article Excerpts about Holoprosencephaly

Holoprosencephaly is a disorder caused by the failure of the prosencephalon (the forebrain of the embryo) to divide to form bilateral cerebral hemispheres, causing defects in the development of the face and in brain structure and function. Once called arhinencephaly, the disorder consists of a spectrum of defects or malformations of the brain and face. (Source: excerpt from NINDS Holoprosencephaly Information Page: NINDS)

Definitions of Holoprosencephaly:

Anterior midline brain, cranial, and facial malformations resulting from the failure of the embryonic prosencephalon to undergo segmentation and cleavage. Alobar prosencephaly is the most severe form and features anophthalmia; cyclopia; severe MENTAL RETARDATION; CLEFT LIP; CLEFT PALATE; SEIZURES; and microcephaly. Semilobar holoprosencepaly is characterized by hypotelorism, microphthalmia, coloboma, nasal malformations, and variable degrees of mental retardation. Lobar holoprosencephaly is associated with mild (or absent) facial malformations and intellectual abilities that range from mild mental retardation to normal. Holoprosencephaly is associated with CHROMOSOME ABNORMALITIES. - (Source - Diseases Database)

Holoprosencephaly is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Holoprosencephaly, or a subtype of Holoprosencephaly, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Holoprosencephaly as a "rare disease".
Source - Orphanet