Hyper-IgM Syndrome

Hyper-IgM Syndrome: Introduction

Hyper-IgM Syndrome: Immunodeficiency with hyper-IgM (HIM) is a rare primary immunodeficiency characterized by the production of normal to increased amounts of IgM antibody of ... more about Hyper-IgM Syndrome.

Hyper-IgM Syndrome: A rare inherited immunodeficiency disorder which causes frequent infections involving the ears, eyes, sinuses, lungs, skin, respiratory tract and other areas of the body. More detailed information about the symptoms, causes, and treatments of Hyper-IgM Syndrome is available below.

Symptoms of Hyper-IgM Syndrome

• Recurring respiratory infections
• Enlarged tonsils
• Enlarged liver
• Enlarged spleen
• Chronic diarrhea
• more symptoms...»

See full list of 21 symptoms of Hyper-IgM Syndrome

Hyper-IgM Syndrome: Complications

Review possible medical complications related to Hyper-IgM Syndrome:

• Opportunistic infections
• Pneumocystis carinii pneumonia
• Non-Hodgkins lymphoma - higher risk of NHL.
• Neurological complications
• Lymphoma
• more complications...»

Medical Textbooks Online about Hyper-IgM Syndrome

Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

Diagnostic Tests for Hyper-IgM Syndrome

• Immune function blood tests
• IgA levels
• IgG levels
• more tests...»

Read more about tests for Hyper-IgM Syndrome

Wrongly Diagnosed with Hyper-IgM Syndrome?

• Misdiagnosis of Hyper-IgM Syndrome
• Failure to diagnose Hyper-IgM Syndrome
• Undiagnosed: Hyper-IgM Syndrome

Causes of Hyper-IgM Syndrome

Read more about causes of Hyper-IgM Syndrome.

Treatments for Hyper-IgM Syndrome

• Intravenous immunogloblulin (IVIG)
• Granulocyte colony-stimulating factor (G-CSF) - for neutropenia
• Antibiotics - for infections or preventive maintenance.
• more treatments...»

Read more about treatments for Hyper-IgM Syndrome

News Archives for Hyper-IgM Syndrome

Medical news articles related to Hyper-IgM Syndrome include:

• Cholesterol Drugs Linked to Increased Fatigue
• Severe Obstetric Complications on the Increase
• Rules Change Could Increase Hospice Use
• Painkillers Linked to Increase in Overdose Deaths
• Depression Linked to Increase in Abdominal Fat
• Use of Kids' Meds on the Increase
• more health news...»

Source: HealthDay News

Videos for Hyper-IgM Syndrome

Patient Surveys for Hyper-IgM Syndrome

• Patient Profile Survey
  Take Survey  View Results
• Survey about the symptoms of your Hyper-IgM Syndrome
  Take Survey  View Results

Reseach about Hyper-IgM Syndrome

Visit our research pages for current research about Hyper-IgM Syndrome treatments.

Hyper-IgM Syndrome: Broader Related Topics

• Primary Immune Deficiency
• Immune disorders
• Immune deficiency conditions
• more types...»

Types of Hyper-IgM Syndrome

Stories from Users Related to Hyper-IgM Syndrome

• Hyper or Hypo? Why aren't I getting any feed back ?
• My migraines suffering increased recently
• Finally a diagnosis...M Cat, please read
• Low IGA IGM help?
• regarding m y health
• daily constant headache with increasing blurry vision
• Mrs.M
• orothostatic hyper or hypotension
• i m in major pain..need help
• Mrs.M.
• diagnosis of celiac in immunodeficiency
• How to Increase Penis Size with Penis Exercises
• Increasing discomfort
• 24 m with urethral irritation please help
• hypergammaglobulinemia
• whats the diseae i m going through

Related forums and medical stories:

• Blood Conditions (129)
  • Anemia - ice chewing
  • small red spots on arms legs back chest
  • Low Platelets, Low white blood count
  • tingly, heavy arms
  • Magnesium Deficiency
  • More user stories

User Interactive Forums

Read about other experiences, ask a question about Hyper-IgM Syndrome, or answer someone else's question, on our message boards:

• I can not get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for this?
• See all the forums.

Article Excerpts about Hyper-IgM Syndrome

Genes and Disease by the National Center for Biotechnology (Excerpt)

Immunodeficiency with hyper-IgM (HIM) is a rare primary immunodeficiency characterized by the production of normal to increased amounts of IgM antibody of questionable quality and an inability to produce sufficient quantities of IgG and IgA. Individuals with HIM are susceptible to recurrent bacterial infections and are at an increased risk of autoimmune disorders and cancer at an early age. (Source: Genes and Disease by the National Center for Biotechnology)

Primary Immune Deficiency, NIAID Fact Sheet: NIAID (Excerpt)

Hyper-IgM is a rare immunodeficiency disease in which the immune system fails to produce IgA and IgG antibodies. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)

Definitions of Hyper-IgM Syndrome:

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Hyper-IgM Syndrome as a "rare disease".
Source - Orphanet