Prevalence and Incidence of Hyper-IgM Syndrome
Ophanet, who are a consortium of European partners,
currently defines a condition rare when if affects 1 person per 2,000.
They list Hyper-IgM Syndrome as a "rare disease".
More information about Hyper-IgM Syndrome is available from Orphanet
Hyper-IgM Syndrome Prevalence: Book Excerpts
Prevalence/Incidence of Hyper-IgM Syndrome: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the prevalence and/or incidence of Hyper-IgM Syndrome.
Acquired immunodeficiency syndrome:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
AIDS results from infection with HIV, which has two forms: HIV-1 and HIV-2. Both forms of HIV have the same modes of transmission and similar opportunistic infections associated with AIDS, but studies indicate that HIV-2 develops more slowly and presents with milder symptoms than HIV-1.
Transmission occurs through contact with infected blood or body fluids and is associated with identifiable high-risk behaviors. It’s disproportionately represented in:
❑ homosexual and bisexual men
❑ persons who use illicit I.V. drugs
❑ neonates of infected females
❑ recipients of contaminated blood or blood products (incidence dramatically decreased since mid-1985)
❑ heterosexual partners of persons in the former groups.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Severe combined immunodeficiency disease:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
SCID is usually transmitted as an autosomal recessive trait, although it may be X-linked. In most cases, the genetic defect seems associated with failure of the stem cell to differentiate into T and B lymphocytes. Many molecular defects such as mutation of the kinase ZAP-70 can cause SCID. X-linked SCID is due to a mutation of a subunit of the interleukin (IL)-2, IL-4, and IL-7 receptors. Less commonly, it results from an enzyme deficiency.
SCID affects more males than females. Its estimated incidence is 1 in every 100,000 to 500,000 births. Most untreated patients die from infection within 1 year of birth.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
About prevalence and incidence statistics:
The term 'prevalence' of Hyper-IgM Syndrome usually refers to the estimated population
of people who are managing Hyper-IgM Syndrome at any given time.
The term 'incidence' of Hyper-IgM Syndrome refers to the annual diagnosis rate,
or the number of new cases of Hyper-IgM Syndrome diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
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