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Diseases » Hyper-IgM Syndrome » Prevalence
 

Prevalence and Incidence of Hyper-IgM Syndrome

Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Hyper-IgM Syndrome as a "rare disease". More information about Hyper-IgM Syndrome is available from Orphanet

Hyper-IgM Syndrome Prevalence: Book Excerpts

Prevalence/Incidence of Hyper-IgM Syndrome: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Hyper-IgM Syndrome.

Acquired immunodeficiency syndrome: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

AIDS results from infection with HIV, which has two forms: HIV-1 and HIV-2. Both forms of HIV have the same modes of transmission and similar opportunistic infections associated with AIDS, but studies indicate that HIV-2 develops more slowly and presents with milder symptoms than HIV-1.

Transmission occurs through contact with infected blood or body fluids and is associated with identifiable high-risk behaviors. It’s disproportionately represented in:

❑ homosexual and bisexual men

❑ persons who use illicit I.V. drugs

❑ neonates of infected females

❑ recipients of contaminated blood or blood products (incidence dramatically decreased since mid-1985)

❑ heterosexual partners of persons in the former groups.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Severe combined immunodeficiency disease: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

SCID is usually transmitted as an autosomal recessive trait, although it may be X-linked. In most cases, the genetic defect seems associated with failure of the stem cell to differentiate into T and B lymphocytes. Many molecular defects such as mutation of the kinase ZAP-70 can cause SCID. X-linked SCID is due to a mutation of a subunit of the interleukin (IL)-2, IL-4, and IL-7 receptors. Less commonly, it results from an enzyme deficiency.

SCID affects more males than females. Its estimated incidence is 1 in every 100,000 to 500,000 births. Most untreated patients die from infection within 1 year of birth.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

About prevalence and incidence statistics:

The term 'prevalence' of Hyper-IgM Syndrome usually refers to the estimated population of people who are managing Hyper-IgM Syndrome at any given time. The term 'incidence' of Hyper-IgM Syndrome refers to the annual diagnosis rate, or the number of new cases of Hyper-IgM Syndrome diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.


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