Causes of Hypogonadism

List of causes of Hypogonadism

Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Hypogonadism) that could possibly cause Hypogonadism includes:

• Testicular dysfunction
• Testicular injury
• Castration
• Laurence-Moon-Biedl syndrome

Causes of Hypogonadism (Diseases Database):

The follow list shows some of the possible medical causes of Hypogonadism that are listed by the Diseases Database:

• Cytotoxic therapeutic agents
• Jaffe-Campanacci syndrome
• Bardet-Biedl syndrome
• Borjeson-Forssman-Lehmann syndrome
• Zinc deficiency
• Laurence-Moon syndrome
• Acrocephalopolysyndactyly type 2
• X-linked mental retardation-hypotonic facies syndrome
• Radiotherapy

Causes of Hypogonadism: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Hypogonadism.

Hypogonadism: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

Primary hypogonadism results directly from interstitial (Leydig’s cell) cellular or seminiferous tubular damage due to faulty development or mechanical damage. This causes increased secretion of gonadotropins by the pituitary in an attempt to increase the testicular functional state and is therefore termed hypergonadotropic hypogonadism. This form of hypogonadism includes Klinefelter syndrome, Reifenstein’s syndrome, Turner syndrome, Sertoli-cell-only syndrome, anorchism, orchitis, and sequelae of irradiation.

Secondary hypogonadism is due to faulty interaction within the hypothalamic-pituitary axis, resulting in failure to secrete normal levels of gonadotropins, and is therefore termed hypogonadotropic hypogonadism. This form of hypogonadism includes hypopituitarism, isolated follicle-stimulating hormone deficiency, isolated luteinizing hormone deficiency, Kallmann’s syndrome, and Prader-Willi syndrome. Depending on the patient’s age at onset, hypogonadism may cause eunuchism (complete gonadal failure) or eunuchoidism (partial failure).

Medications, such as exogenous testosterone or anabolic steroids, can also cause of hypogonadism, resulting in infertility.

Hypogonadism is rare, and it has no racial predilection.

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School Underachievement and Academic Failure: Principal Causes of School Underachievement and AcademicFailure
(The Diagnostic Approach to Symptoms and Signs in Pediatrics)

1. Environmentaldisadvantage
2. Impaired intellectual ability
3. Impaired hearing, language, or vision
4. Specific learning disabilities
5. Medical illness in the absence of psychosis
6. Psychologic disorders
   1. Anxiety
   2. Depression
   3. Attention deficit hyperactivity disorder
   4. School phobia
   5. Adjustment reaction of childhood andadolescence
   6. Disruptive behavior disorders
   7. Bipolar disorder
   8. Pervasive developmental disorders
      1. Autism
      2. Childhood disintegrative disorder
      3. Asperger disorder
      4. Rett syndrome
      5. Pervasive developmental disorder nototherwise specified
   9. Psychosis
   10. Substance use

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Hypogonadism as a complication of other conditions:

Other conditions that might have Hypogonadism as a complication may, potentially, be an underlying cause of Hypogonadism. Our database lists the following as having Hypogonadism as a complication of that condition:

• Klinefelter syndrome

Hypogonadism as a symptom:

Conditions listing Hypogonadism as a symptom may also be potential underlying causes of Hypogonadism. Our database lists the following as having Hypogonadism as a symptom of that condition:

• 3-M Syndrome
• 46,XX Gonadal dysgenesis epibulbar dermoid
• Alagille Syndrome
• Alopecia - hypogonadism - extrapyramidal disorder
• Anophthalmia - hypyothalamo-pituitary insufficiency
• Anophthalmia - microcephaly - hypogonadism
• Aromatase deficiency
• Bardet-Biedl Syndrome
• Bardet-Biedl syndrome, type 1
• Bardet-Biedl syndrome, type 10
• Bardet-Biedl syndrome, type 11
• Bardet-Biedl syndrome, type 12
• Bardet-Biedl syndrome, type 2
• Bardet-Biedl syndrome, type 3
• Bardet-Biedl syndrome, type 4
• Bardet-Biedl syndrome, type 5
• Bardet-Biedl syndrome, type 6
• Bardet-Biedl syndrome, type 7
• Bardet-Biedl syndrome, type 8
• Bardet-Biedl syndrome, type 9
• Borjeson Syndrome
• Bosma-Henkin-Christiansen syndrome
• Camera-Marugo-Cohen syndrome
• Camurati-Engelmann Disease
• Cardiomyopathy - hypogonadism - metabolic anomalies
• CCFDN
• Chromosome 13p duplication
• Chromosome 15 Ring
• Chromosome 15q duplication syndrome
• Chromosome 15q, partial deletion
• Chromosome 3, monosomy 3p
• Chromosome 3, trisomy 3p
• Chromosome 6p deletion syndrome
• Congenital disorder of glycosylation type 1A
• Congenital disorder of glycosylation type 1K
• De Sanctis-Cacchione syndrome
• Freire-Maia odontotrichomelic syndrome
• Grahmann's syndrome
• Harper dwarfism
• Hypogonadism - mitral valve prolapse - mental retardation
• Hypogonadism, primary - partial alopecia
• Keratoderma - epithelioma - dental abnormalities- hypogonadism
• Luteinizing hormone releasing hormone, deficiency of, with ataxia
• Meier-Rotschild syndrome
• Mental retardation - dysmorphism - hypogonadism - diabetes
• Mental retardation - epileptic seizures - hypogonadism - hypogenitalism -microcephaly - obesity
• Mental retardation X-linked syndromic 7
• Mental retardation, X-linked - hypogonadism - ichthyosis - obesity - short stature
• Mental retardation, X-linked - hypotonic face
• Microcephaly - hypergonadotropic hypogonadism - short stature
• Moebius axonal neuropathy - hypogonadism
• Multiple endocrine abnormalities - adenylyl cyclase dysfunction
• Multiple pterygium syndrome
• Muscular dystrophy - congenital infantile cataract - hypogonadism
• Muscular dystrophy, congenital, infantile with cataract - hypogonadism
• Myhre-Ruvalcaba-Kelley syndrome
• Prader-Willi syndrome
• Renpenning syndrome 1
• Resistance to LH (luteinizing hormone)
• Ruvalcaba-Churesigaew-Myhre syndrom
• Salti-Salem syndrome
• Say-Barber-Miller syndrome
• Schäfer syndrome
• Schaap-Taylor-Baraitser syndrome
• Scholte syndrome
• Sohval-Soffer syndrome
• Spastic paraplegia with Kallmann syndrome
• Vagneur Triolle Ripert syndrome
• Vasquez Hurst Sotos syndrome
• Werner syndrome
• X chromosome, duplication Xq13 1 q21 1
• X chromosome, trisomy 26-28
• X chromosome, trisomy Xp3
• X chromosome, trisomy Xpter Xq13
• X chromosome, trisomy Xq
• X chromosome, trisomy Xq25
• Zinc deficiency

Related information on causes of Hypogonadism:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Hypogonadism may be found in:

• Hidden causes of Hypogonadism