Prevalence and Incidence of Hypoparathyroidism
Hypoparathyroidism: Rare Disease
Hypoparathyroidism is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Hypoparathyroidism, or a subtype of Hypoparathyroidism,
affects less than 200,000 people in the US population.
Hypoparathyroidism Prevalence: Book Excerpts
More Statistics about Hypoparathyroidism:
Hospitalization statistics
All statistics for Hypoparathyroidism
Prevalence/Incidence of Hypoparathyroidism: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the prevalence and/or incidence of Hypoparathyroidism.
Hypoparathyroidism:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
Hypoparathyroidism may be acute or chronic and is classified as idiopathic or acquired. The acquired form may also be reversible. Idiopathic hypoparathyroidism may result from an autoimmune genetic disorder or the congenital absence of the parathyroid glands. Acquired hypoparathyroidism commonly results from accidental removal of or injury to one or more parathyroid glands during thyroidectomy or other neck surgery; rarely it results from massive thyroid irradiation. It may also result from ischemic infarction of the parathyroids during surgery or from hemochromatosis, sarcoidosis, amyloidosis, tuberculosis, neoplasms, or trauma. An acquired, reversible hypoparathyroidism may result from hypomagnesemia-induced impairment of hormone synthesis, from suppression of normal gland function due to hypercalcemia, or from delayed maturation of parathyroid function. (See What happens in acute hypoparathyroidism.)
PTH isn’t regulated by the pituitary or hypothalamus. It normally maintains blood calcium levels by increasing bone resorption and GI absorption of calcium. It also maintains an inverse relationship between serum calcium and phosphate levels by inhibiting phosphate reabsorption in the renal tubules. Abnormal PTH production disrupts this balance. The incidence is 4 out of 100,000 people. Incidence of the idiopathic and reversible forms is highest in children; that of the irreversible acquired form, in older patients who have undergone surgery for hyperthyroidism or other head and neck conditions.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Hypoparathyroidism:
Hypoparathyroidism - epidemiology
(The 5-Minute Pediatric Consult)
Many normal neonates can have hypocalcemia (serum calcium >8 mg/dL) during the 1st 3 weeks of life owing to physiologic transient hypoparathyroidism.
- Parathyroid gland immaturity can lead to deficient PTH release and exaggerated normal fall in serum calcium concentration during the 1st 3 days of life.
- Relative immaturity of renal phosphorus handling and response to PTH can lead to late neonatal hypocalcemia precipitated by a high phosphate diet (cow’s milk-based formulas).
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
About prevalence and incidence statistics:
The term 'prevalence' of Hypoparathyroidism usually refers to the estimated population
of people who are managing Hypoparathyroidism at any given time.
The term 'incidence' of Hypoparathyroidism refers to the annual diagnosis rate,
or the number of new cases of Hypoparathyroidism diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
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