TREATMENTS &
RESEARCH

Search the
latest
treatment
information
here.

Dr. Huntley's
Diagnosis
Checklist

Have a symptom?
See what questions
a doctor would ask.

Diseases » Hypothermia » Clinical Trials

Clinical Trials for Hypothermia

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Hypothermia is grouped into the following categories:-

View by trial name

View by drugs used in Hypothermia clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Hypothermia:

Hypothermia During Intracranial Aneurysm Surgery Trial - This study has been completed (Current: 23 Nov 2006)
Hypothermia to Treat Severe Brain Injury - This study is no longer recruiting patients (Current: 23 Nov 2006)
Newborn Thermal Care Practices: A Community Based Program to Prevent Hypothermia - This study is currently recruiting patients (Current: 23 Nov 2006)
Clinical and Economical Interest of Endovascular Cooling in the Management of Cardiac Arrest (ICEREA Study) - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
Safety Study to Evaluate the Effect of Lowering Body Temperature During Cochlear Implantation - This study is currently recruiting patients (Current: 23 Nov 2006)
Dexmed/Buspirone Synergism on Shivering - This study is currently recruiting patients (Current: 23 Nov 2006) - dexmedetomidine,buspirone
TOBY: a Study of Treatment for Perinatal Asphyxia - This study is currently recruiting patients (Current: 23 Nov 2006)
(NABIS:H) National Acute Brain Injury Study: Hypothermia - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
Hypothermia in Traumatic Brain Injury in Children (HiTBIC) - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke - This study is currently recruiting patients (Current: 23 Nov 2006) - tissue plasminogen activator
Caffeinol Hypothermia Protocol - This study is currently recruiting patients (Current: 23 Nov 2006) - Caffeinol
Pilot Community Clinical Study of Hypothermia in Cardiac Arrest - This study has been completed (Current: 23 Nov 2006)
Fluid Shifts in Patients Treated With Therapeutic Hypothermia After Cardiac Arrest - This study is currently recruiting patients (Current: 23 Nov 2006) - HyperHAES vs. RA-solution/NaCl
Pilot Clinical Study of the LRS ThermoSuit System in Post Arrest Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
Induction of Mild Hypothermia Following Out-of-Hospital Cardiac Arrest - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
A Comparison of Prevention of Hypothermia in Pediatric Patient Between Wrapping With Cotton and Plastic. - This study has been completed (Current: 23 Nov 2006)
Body Cooling for Birth Asphyxia in Term Infants - This study is no longer recruiting patients (Current: 23 Nov 2006)
Therapeutic Hypothermia for Severe Traumatic Brain Injury in Japan - This study is currently recruiting patients (Current: 23 Nov 2006)
CoolCap Trial, Treatment of Perinatal Hypoxic-Ischemic Encephalopathy - This study has been completed (Current: 23 Nov 2006)
Phase III Hypothermia Clinical Trial - This study is not yet open for patient recruitment (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Hypothermia

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Hypothermia:

Buspirone - Dexmed/Buspirone Synergism on Shivering - This study is currently recruiting patients (Current: 23 Nov 2006)
Caffeinol - Caffeinol Hypothermia Protocol - This study is currently recruiting patients (Current: 23 Nov 2006)
Dexmedetomidine - Dexmed/Buspirone Synergism on Shivering - This study is currently recruiting patients (Current: 23 Nov 2006)
HyperHAES vs. RA-solution/NaCl - Fluid Shifts in Patients Treated With Therapeutic Hypothermia After Cardiac Arrest - This study is currently recruiting patients (Current: 23 Nov 2006)
Tissue Plasminogen Activator - Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke - This study is currently recruiting patients (Current: 23 Nov 2006)

The trial data on this page has been sourced from