Causes of Immune deficiency conditions
List of causes of Immune deficiency conditions
Following is a list of causes or underlying conditions
(see also Misdiagnosis of underlying causes of Immune deficiency conditions)
that could possibly cause Immune deficiency conditions includes:
- Other types of immune deficiency
- Various serious illnesses:
- Juvenile Scleroderma - impaired immune system
- Myelodysplastic syndrome
- Renal failure, acute
- C3 deficiency, hereditary
- Diabetes mellitus type 1
- Prednisolone
- Centromeric instability of chromosomes 1,9 and 16 and immunodeficiency
- Efalizumab
- Non-Hodgkin's lymphoma
- Roifman syndrome - immune deficiency
- Velocardiofacial syndrome
- Diabetes mellitus type 2
- Starvation (acute)
- Anakinra
- Ataxia telangiectasia - weak immune system
- Brequinar
- X-linked lymphoproliferative disease
- Philadelphia-negative chronic myeloid leukemia - susceptibility to infection
- Leukemia, Monocytic, Acute - susceptibility to infection
- Adenosine deaminase deficiency
- Common variable hypogammaglobulinaemia
- Paroxysmal nocturnal haemoglobinuria
- Tacrolimus
- Chediak-Higashi disease
- Mizoribine
- Atypical mycobacteriosis, familial
- Spondylometaphyseal dysplasia with combined immunodeficiency - immune deficiency
- Scleroderma - impaired immune system
- Microcephalic primordial dwarfism, Toriello type - immune deficiency
- Immunologic Deficiency Syndromes - impaired immune system
- Chromosome 22, microdeletion 22q11 - impaired immune system
- Hyposplenism
- Kostmann disease
- Leucocyte adhesion deficiency type 1
- Sickle cell disease
- Alemtuzumab
- Renal failure, chronic
- Infliximab
- Autoimmune polyendocrine syndrome type 1
- Multiple Myeloma - immune deficiency
- Leukocyte adhesion deficiency (LAD) - impaired immune system
- Chromosome 22q deletion - weak immune system
- Myotonic dystrophy
- Hepatic failure
- Marasmus
- Splenectomy
- Vitamin H deficiency
- Major histocompatibility complex class I deficiency
- Bloom's syndrome
- Hodgkin's Disease - immune deficiency
- Immunodeficiency, combined, severe, due to ZAP70 deficiency - susceptibility to infection
- Acute lymphoblastic leukemia
- Cyclical neutropenia
- OLEDAID - weak immune system
- Kotzot-Richter syndrome - weak immune system
- Immunodeficiency with short limb dwarfism - weak immune system
- Acute myeloid leukemia
- Myeloperoxidase deficiency
- Chronic lymphocytic leukaemia
- Mycophenolate mofetil
- Glucocorticoids, topical
- Malabsorption syndrome
- Hairy cell leukaemia
- Multiple carboxylase deficiency, propionic acidemia - impaired immune system
- Complement levels low (serum or plasma)
- Cachexia
- Hypersplenism
- Methotrexate
- DiGeorge's syndrome - immune deficiency
- Myeloma
- X-linked hyperimmunoglobulin M syndrome
- Chronic granulomatous disease
- Semmerkrot-Haraldsson-Weenaes syndrome - immune deficiency
- Lysinuric protein intolerance - immune deficiency
- Hyperimmunoglobulin E (IgE) syndrome
- Chromosome 22q11.2 deletion syndrome - weak immune system
- Paraneoplastic syndrome
- Pentostatin
- Visceral leishmaniasis
- Wiskott-Aldrich syndrome
- Recurrent hereditary polyserositis
- HIV-1 disease
Causes of Immune deficiency conditions (Diseases Database):
The follow list shows some of the possible medical causes of Immune deficiency conditions
that are listed by the Diseases Database:
Source: Diseases Database
Immune deficiency conditions Causes: Book Excerpts
Immune deficiency conditions as a complication of other conditions:
Other conditions that might have
Immune deficiency conditions as a complication may,
potentially, be an underlying cause of Immune deficiency conditions.
Our database lists the following as having
Immune deficiency conditions as a complication of that condition:
Immune deficiency conditions as a symptom:
Conditions listing Immune deficiency conditions
as a symptom may also be potential underlying causes of Immune deficiency conditions.
Our database lists the following as having
Immune deficiency conditions as a symptom of that condition:
- Acute lymphoblastic leukemia
- Acute lymphoblastic leukemia, adult
- Acute lymphocytic leukemia
- Ataxia Telangiectasia
- DiGeorge's syndrome
- Hyperdibasic aminoaciduria type 2
- Leukemia, Lymphocytic, Acute, L1
- Leukemia, Lymphocytic, Acute, L2
- Leukemia, Lymphocytic, Acute, L3
- Leukemia, Myeloid, Philadelphia-Negative
- Leukemia, Myeloid, Philadelphia-Positive
- Lysinuric protein intolerance
- Microcephalic primordial dwarfism, Toriello type
- Multiple Myeloma
- Roifman syndrome
- Semmerkrot-Haraldsson-Weenaes syndrome
- Spondylometaphyseal dysplasia with combined immunodeficiency
- T-cell acute lymphoblastic leukemia
Medications or substances causing Immune deficiency conditions:
The following drugs, medications, substances or toxins are some of the possible
causes of Immune deficiency conditions as a symptom.
This list is incomplete and various other drugs or substances
may cause your symptoms.
Always advise your doctor of any medications or treatments you are using,
including prescription, over-the-counter, supplements, herbal or alternative treatments.
Read more about medication causes of Immune deficiency conditions
Medical news summaries relating to Immune deficiency conditions:
The following medical news items are relevant to causes of Immune deficiency conditions:
Related information on causes of Immune deficiency conditions:
As with all medical conditions,
there may be many causal factors.
Further relevant information on causes of Immune deficiency conditions may be found in:
Causes of Immune deficiency conditions: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the causes of Immune deficiency conditions.
Severe combined immunodeficiency disease:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
SCID is usually transmitted as an autosomal recessive trait, although it may be X-linked. In most cases, the genetic defect seems associated with failure of the stem cell to differentiate into T and B lymphocytes. Many molecular defects such as mutation of the kinase ZAP-70 can cause SCID. X-linked SCID is due to a mutation of a subunit of the interleukin (IL)-2, IL-4, and IL-7 receptors. Less commonly, it results from an enzyme deficiency.
SCID affects more males than females. Its estimated incidence is 1 in every 100,000 to 500,000 births. Most untreated patients die from infection within 1 year of birth.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Common variable immunodeficiency:
Causes
(Professional Guide to Diseases (Eighth Edition))
The cause of common variable immunodeficiency is unknown. Most patients have a normal circulating B-cell count but defective synthesis or release of immunoglobulins. Many also exhibit progressive deterioration of T-cell (cell-mediated) immunity revealed by delayed hypersensitivity skin testing.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Acquired immunodeficiency syndrome:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
AIDS results from infection with HIV, which has two forms: HIV-1 and HIV-2. Both forms of HIV have the same modes of transmission and similar opportunistic infections associated with AIDS, but studies indicate that HIV-2 develops more slowly and presents with milder symptoms than HIV-1.
Transmission occurs through contact with infected blood or body fluids and is associated with identifiable high-risk behaviors. It’s disproportionately represented in:
❑ homosexual and bisexual men
❑ persons who use illicit I.V. drugs
❑ neonates of infected females
❑ recipients of contaminated blood or blood products (incidence dramatically decreased since mid-1985)
❑ heterosexual partners of persons in the former groups.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Severe combined immunodeficiency disease:
Causes
(Handbook of Diseases)
SCID is usually transmitted as an autosomal recessive trait, although it may be X-linked. In most cases, the genetic defect seems associated with failure of the stem cell to differentiate into T and B lymphocytes.
Many molecular defects, such as mutation of the kinase ZAP-70, can cause SCID. X-linked SCID results from a mutation of a subunit of the interleukin-2 (IL-2), IL-4, and IL-7 receptors. Less commonly, it results from an enzyme deficiency.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Common variable immunodeficiency:
Causes
(Handbook of Diseases)
Exactly what causes common variable immunodeficiency is unknown. Most patients have a normal circulating B-cell count but defective synthesis or release of immunoglobulins. Many also exhibit progressive deterioration of T-cell (cell-mediated) immunity, which is revealed by delayed hypersensitivity skin testing.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Human immunodeficiency virus infection:
Causes
(Handbook of Diseases)
The virus has two major strains: HIV-1, which is closely related to the primate retrovirus called simian immunodeficiency virus, and HIV-2, which is associated with immunodeficiency but less pathogenic that HIV-1, results from infection with HIV, which strikes cells bearing the CD4+ antigen; the latter (normally a receptor for major histocompatibility complex molecules) serves as a receptor for the retrovirus and lets it enter the cell. HIV prefers to infect the CD4+ lymphocyte or macrophage but may also infect other CD4+ antigen-bearing cells of the GI tract, uterine cervical cells, and neuroglial cells. The virus gains access by binding to the CD4+ molecule on the cell surface along with a co-receptor (thought to be the receptor CCR5). After invading a cell, HIV either replicates, which leads to cell death, or becomes latent. HIV infection leads to profound pathology, either directly, through destruction of CD4+ T cells, other immune cells, and neuroglial cells, or indirectly, through the secondary effects of CD4+ T-cell dysfunction and resultant immunosuppression.
The infection process takes three forms:
❑ immunodeficiency (opportunistic infections and unusual cancers)
❑ autoimmunity (lymphoid interstitial pneumonia, arthritis, hypergammaglobulinemia, and production of autoimmune antibodies)
❑ neurologic dysfunction (AIDS dementia complex, HIV encephalopathy, and peripheral neuropathies).
Transmission
HIV is transmitted by direct inoculation during intimate sexual contact, especially associated with the mucosal trauma of receptive rectal intercourse; transfusion of contaminated blood or blood products (a risk diminished by routine testing of all blood products); sharing of contaminated needles; or transplacental or postpartum transmission from an infected mother to the fetus (by cervical or blood contact at delivery and in breast milk).
HIV isn’t transmitted by casual household or social contact. The average time between exposure to the virus and diagnosis is 8 to 10 years, but shorter and longer incubation times have also been recorded. Most people develop antibodies within 6 to 8 weeks of contracting the virus.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
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