Prevalence and Incidence of Immune Thrombocytopenic Purpura

Prevalance of Immune Thrombocytopenic Purpura:

rare. ... see also overview of Immune Thrombocytopenic Purpura.

Immune Thrombocytopenic Purpura: Rare Disease

Immune Thrombocytopenic Purpura is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Immune Thrombocytopenic Purpura, or a subtype of Immune Thrombocytopenic Purpura, affects less than 200,000 people in the US population.

Immune Thrombocytopenic Purpura Prevalence: Book Excerpts

• Causes and incidence - Allergic purpuras
• Causes and incidence - Idiopathic thrombocytopenic purpura
• Purpura Fulminans - epidemiology - Purpura Fulminans

Prevalence/Incidence of Immune Thrombocytopenic Purpura: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Immune Thrombocytopenic Purpura.

Allergic purpuras: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

The most common identifiable cause of allergic purpura is probably an autoimmune reaction directed against vascular walls, triggered by a bacterial infection (particularly streptococcal infection). Typically, upper respiratory tract infection occurs 1 to 3 weeks before the onset of symptoms. Other possible causes include allergic reactions to some drugs and vaccines, to insect bites, and to some foods (such as wheat, eggs, milk, and chocolate).

Allergic purpura affects more males than females and is most prevalent in children ages 3 to 7. The prognosis is more favorable for children than adults.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Idiopathic thrombocytopenic purpura: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

ITP may be an autoimmune disorder, because antibodies that reduce the life span of platelets have been found in nearly all patients. The spleen probably helps to remove platelets modified by the antibody. Acute ITP usually follows a viral infection, such as rubella or chickenpox, and can follow immunization with a live virus vaccine. Chronic ITP seldom follows infection and is commonly linked to immunologic disorders such as systemic lupus erythematosus. It’s also linked to drug reactions. ITP frequently occurs in patients who have abused alcohol, heroin, or morphine, and in patients with acquired immunodeficiency syndrome who are exposed to the rubella virus.

Acute ITP usually affects children between ages 2 and 6; chronic ITP mainly affects adults younger than age 50, especially women between ages 20 and 40.

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Source: Professional Guide to Diseases (Eighth Edition), 2005

Purpura Fulminans: Purpura Fulminans - epidemiology
(The 5-Minute Pediatric Consult)

Depends on underlying cause

Purpura Fulminans - incidence

• Neonatal purpura fulminans related to homozygous protein C deficiency: 1 in 250,000–500,000 births
• Homozygous protein S deficiency is more rare.

Purpura Fulminans - prevalence

Purpura frequently seen in bacterial sepsis with meningococcus and other pathogens

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008

About prevalence and incidence statistics:

The term 'prevalence' of Immune Thrombocytopenic Purpura usually refers to the estimated population of people who are managing Immune Thrombocytopenic Purpura at any given time. The term 'incidence' of Immune Thrombocytopenic Purpura refers to the annual diagnosis rate, or the number of new cases of Immune Thrombocytopenic Purpura diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.

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