INDIGESTION
INDIGESTION: Excerpt from Differential Diagnosis in Primary Care
This is a vague term, and if the patient is put on the spot, he or she will usually describe the problem as heartburn, regurgitation of water brash, fullness in the stomach, or frequent belching following meals. Usually the patient"s appetite is not affected nor is there any weight loss.

INDIGESTION
The causes are easy to arrive at by merely asking the question, “Why would food cause these symptoms?” Obviously, the food or drink ingested may be the source of irritation: spicy foods, coffee, alcohol, excessive fried food (which actually suppresses the secretion of gastric juice and slows gastric emptying), and insufficiently masticated food. The patient may sometimes be allergic to a particular food.
The upper GI tract may be already irritated with reflux esophagitis from a hiatal hernia, gastritis, or gastric or duodenal ulcer, or it may be partially obstructed by a carcinoma of the esophagus or stomach or a pyloric ulcer. Chronic appendicitis and regional ileitis may cause partial obstruction or paralytic ileus. There may be diminished secretion of GI juices in pernicious anemia, cholecystitis, cholelithiasis, hepatitis, chronic pancreatitis, or pancreatic carcinoma or in patients with previous gastrectomies.
There may be a systemic illness that is associated with GI irritation or paralytic ileus. In this category, one must consider congestive heart failure, electrolyte disturbances such as hypokalemia (diuretics) or hyperkalemia (Addison disease) and abdominal angina, migraine, or epilepsy. Anemia and diabetic acidosis may produce similar symptoms.
Is there another way of recalling these conditions that may be simpler? Yes, the application of the “target” method to the anatomy of the internal organs. In the “bull”s-eye” one would think of the esophagus and stomach (esophagitis, esophageal carcinoma, gastritis, gastric ulcer, and gastric carcinoma); in the next circle one would consider gallbladder, pancreatic, liver, and heart diseases; and, in the final circle, kidney, CNS, hormonal alterations, and other systemic diseases.
A third approach is simply to apply the mnemonic MINT to the organs of the upper abdomen. It is recommended that the reader apply this method as an exercise. Table 41 applies the mnemonic VINDICATE to the same organs.
TABLE 41. INDIGESTION
| |
V |
I |
N |
D |
I |
C |
A |
T |
E |
| |
Vascular |
Inflammatory |
Neoplasm |
Degenerative |
Intoxication Idiopathic |
Congenital |
Autoimmune Allergic |
Trauma |
Endocrine |
Esophagus |
Varices |
Esophagitis |
Esophageal carcinoma |
Plummer-Vinson syndrome |
Lye stricture |
Hiatal hernia |
Scleroderma |
|
|
| |
|
|
|
|
|
Diverticulitis |
|
|
|
| |
|
|
|
|
|
Barrett esophagitis |
|
|
|
Stomach |
|
Gastritis Ulcer |
Carcinoma |
Atrophic gastritis |
Aspirin |
Cascade stomach |
|
Gastrectomy |
Zollinger–Ellison syndrome |
| |
|
|
|
Pernicious anemia |
Steroids |
|
|
|
|
| |
|
|
|
|
Reserpine |
|
|
|
|
| |
|
|
|
|
Alcohol |
|
|
|
|
| |
|
|
|
|
Coffee |
|
|
|
|
Duodenum and Small Intestines |
Abdominal angina |
Duodenitis Ulcer |
Polyp |
|
|
Diverticuli |
Scleroderma |
Gastrectomy with afferent loop obstruction |
Zollinger–Ellison syndrome |
| |
|
|
|
|
|
|
|
|
Uremic ulcer |
Gallbladder |
|
Cholecystitis |
Cholangiocarcinoma |
|
|
Stones from sickle cell anemia |
|
Calculus |
|
Liver |
Congestive heart failure |
Infectious hepatitis |
Hepatoma Metastatic carcinoma |
Cirrhosis |
Alcoholic cirrhosis |
|
|
|
|
Pancreas |
|
Pancreatitis |
Pancreatic carcinoma |
|
|
Fibrocystic disease |
|
|
Hyperparathyroidism |
Kidney |
|
Pyelonephritis |
|
|
Uremia |
|
|
Calculus |
|
Approach to the Diagnosis
The association of other symptoms and signs is important. If there is relief by antacids, esophagitis, gastritis, or an ulcer may be present. If there is blood in the stool, one should suspect an ulcer or carcinoma. Radiographic studies in the form of an upper GI series and esophagram, cholecystogram, and barium enema are usually indicated. A gastric analysis, esophagoscopy, and gastroscopy often need to be done. Awareness that a systemic disease such as an electrolyte disturbance or uremia may be the cause will suggest the need for other studies, especially if there are systemic symptoms, fever, or shortness of breath.
Other Useful Tests
- Esophageal motility studies (cardiospasm, reflux esophagitis)
- Ambulatory pH monitoring (reflux esophagitis)
- Bernstein test (reflux esophagitis)
- Gallbladder sonogram (cholecystitis)
- CT scan of the abdomen (neoplasm abscess, pancreatitis)
- Serial ECGs and cardiac enzymes (myocardial infarction)
- Circulation time (CHF)
Book Source Details
- Book Title: Differential Diagnosis in Primary Care
- Author(s): R. Douglas Collins
- Year of Publication: 2007
- Copyright Details: Differential Diagnosis in Primary Care, Copyright © 2007 Lippincott Williams & Wilkins.
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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.
» Next page: Dyspepsia (Handbook of Signs & Symptoms (Third Edition))
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