Clinical Trials for Insulin Resistance

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Insulin Resistance is grouped into the following categories:-

• View by trial name
• View by drugs used in Insulin Resistance clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Insulin Resistance:

• Rosiglitazone to Reverse Metabolic Defects in Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides. - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosiglitazone,Fenofibrate
• Effect of Leptin Therapy in the Treatment of Severe Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006) - hu Leptin (A-100)
• Efficacy Pilot Study of Triflusal in the Attenuation of Insulin Resistance in Human Obesity - This study has been completed (Current: 23 Nov 2006) - Triflusal (DCI)
• Study of Recombinant Human Insulin-Like Growth Factor I in Patients With Severe Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006) - insulin-like growth factor I
• Effects of Oral Glucosamine on Insulin and Blood Vessel Activity in Normal and Obese People - This study is currently recruiting patients (Current: 23 Nov 2006) - Glucosamine Hydrochloride
• Tight Glycemic Control in Critical Care Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• Cytochrome P450 2E1 and Iron Overload - This study has been completed (Current: 23 Nov 2006)
• Influence of Insulin on BP Change During Adolescence - This study has been completed (Current: 23 Nov 2006)
• Glucolipotoxicity and Cardiac Dysfunction in Obesity - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Treatment of Insulin Resistance in Hypertensive, Obese Adolescents - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Telmisartan
• The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction - This study is currently recruiting patients (Current: 23 Nov 2006)
• Integrating the Genetic and Metabolic Faces of Obesity - This study is currently recruiting patients (Current: 23 Nov 2006) - thiazolidinedione
• Study of How Exercise or Weight Loss Effects Metabolic Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Study of Niacin and Rosiglitazone in Dysmetabolic Dyslipidemia - This study has been completed (Current: 23 Nov 2006) - fenofibrate,niacin,rosiglitazone
• Mechanisms of Insulin Resistance in Humans - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - 20% Intralipid,Salicylate
• Substrate Cycling in Energy Metabolism - This study is no longer recruiting patients (Current: 23 Nov 2006) - fenofibrate
• Does Olanzapine Increase the Risk of Developing Diabetes? - This study is currently recruiting patients (Current: 23 Nov 2006)
• Investigator Initiated Study of the Effects of Androgen Therapy on Carbohydrate and Lipid Metabolism In Elderly Men - This study is currently recruiting patients (Current: 23 Nov 2006) - Topical testosterone (Androgel) 10 g/day
• Pegylated-Interferon and Ribavirin Plus Metformin in the Treatment of Chronic HCV Infection and Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006) - metformin
• Metabolic Study of Concentric and Eccentric Muscle Training - This study has been completed (Current: 23 Nov 2006)
• Treating the Endothelium to Restore Insulin Sensitivity - This study is currently recruiting patients (Current: 23 Nov 2006) - Losartan
• Study In Patients With Insulin Resistance - This study has been completed (Current: 23 Nov 2006) - Avandia
• Diet, Exercise &/or Rosiglitazone for HIV-Associated Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosiglitazone insulin sensitizing agent
• Efficacy Study of Panax Ginseng to Boost Antipsychotics Effects in Schizophrenia - This study is no longer recruiting patients (Current: 23 Nov 2006) - Panax Ginseng
• Pioglitazone as a Treatment for Lipid and Glucose Abnormalities In Patients With Schizophrenia - This study is currently recruiting patients (Current: 23 Nov 2006) - Pioglitazone
• Exercise in Insulin-Resistant Minority Adolescents - This study is currently recruiting patients (Current: 23 Nov 2006)
• Genetic Studies of Insulin and Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Resistance Atherosclerosis Study (IRAS) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Insulin Resistance and Blood Pressure Regulation in Blacks - This study has been completed (Current: 23 Nov 2006)
• Insulin and Biogenic Amines in Cardiovascular Disease - This study has been completed (Current: 23 Nov 2006)
• Central Obesity and Disease Risk in Japanese Americans - This study has been completed (Current: 23 Nov 2006)
• Genetics of the Metabolic Syndrome in Japanese Americans - This study has been completed (Current: 23 Nov 2006)
• Insulin, Androgen, and Risk in African-American Women - This study has been completed (Current: 23 Nov 2006)
• Diet, Insulin Resistance, and Cardiovascular Risk - This study has been completed (Current: 23 Nov 2006)
• Lipoprotein Metabolism in Hypertensive African-Americans - This study has been completed (Current: 23 Nov 2006)
• Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy Syndrome - This study has been completed (Current: 23 Nov 2006) - Avandia administration for 6-12 weeks
• Bypass Angioplasty Revascularization Investigation in Type 2 Diabetics (BARI 2D) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Hypoglycemic Agents
• Influence of Insulin on BP Change During Adolescence - This study is no longer recruiting patients (Current: 23 Nov 2006)
• A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes) - This study has been completed (Current: 23 Nov 2006) - Metformin,pioglitazone,rosiglitazone
• Prenatal Nutrition and Adult Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone and Exercise Training: Effects on HIV-Infected People With Insulin Resistance, Hypertriglyceridemia, and Adipose Tissue Maldistribution - This study has been completed (Current: 23 Nov 2006) - rosiglitazone (Avandia)
• VA HDL Intervention Trial (VA-HIT) Ancillary Study Data Analysis - This study has been completed (Current: 23 Nov 2006)
• Epidemiology of Stress and the Metabolic Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Genomewide Search for Loci Underlying Metabolic Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Family Linkage Study of Obstructive Sleep Apnea (OSA) in Iceland - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans - This study has been completed (Current: 23 Nov 2006) - DHEA
• Use of a Nutritional Supplement to Treat Diabetic Symptoms in HIV-Infected Adults - This study is currently recruiting patients (Current: 23 Nov 2006) - Chromium piccolinate
• Insulin Resistance and Testosterone in Women - This study is currently recruiting patients (Current: 23 Nov 2006) - metformin,leuprolide acetate
• Chromium Picolinate for the Treatment of Metabolic Syndrome - This study has been completed (Current: 23 Nov 2006) - Chromium picolinate
• Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Dietary supplement for weight loss
• Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006) - Recombinant Human Growth Hormone,Rosiglitazone
• The Effects of Calorie Restriction With or Without Metformin on Weight and Insulin Resistance - This study has been completed (Current: 23 Nov 2006) - metformin
• The Primary Objective of This Study is to Determine Whether MICARDIS Improves Insulin Sensitivity in Overweight or Obese, Non-Diabetic, Normotensive Subjects. - This study has been completed (Current: 23 Nov 2006) - MICARDIS® (telmisartan)
• Determining the Responsiveness of Intestinal Lipoprotein Production to an Elevation of Plasma Free Fatty Acids - This study is currently recruiting patients (Current: 23 Nov 2006) - Intralipid,leucine, glycerol
• ARREST PAD (Peripheral Arterial Disease) - This study is currently recruiting patients (Current: 23 Nov 2006) - atorvastatin,rosiglitazone
• The Roles of Cytokines in the Mechanism of Insulin Resistance and Energy Balance - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Role of Insulin Resistance in PCOS - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overweight Patients With High Blood Pressure to Respond to Insulin - This study has been completed (Current: 23 Nov 2006) - Olmesartan medoxomil,Losartan potassium,Atenolol
• Correlation Between Continuous Glucose Monitoring and Intermittent Glucose Monitoring Values and Pregnancy Outcomes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Peripheral Effects of Exercise on Cardiovascular Health (STRRIDE I) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Oral Contraceptives in the Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Ortho Tri Cyclen
• A Study to Examine Changes in GIP Plasma Levels Following Gastric Bypass Surgery in Obese Patients - This study has been suspended (Current: 23 Nov 2006)
• He Purongo Mo Nga Kai Hei Arai i Te Matehuka Dietary Diabetes Prevention Study for Maori - This study has been completed (Current: 23 Nov 2006)
• Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - pioglitazone,nateglinide,placebo
• Relation of Inflammation and Insulin Resistance to Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosiglitazone,Atorvastatin
• Relation of Obesity With Frequency of Meals (MST 0557) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Research on the Nature, Diagnosis, and Treatment of Obesity and Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Resistance in Patients With Mood Disorder - This study is currently recruiting patients (Current: 23 Nov 2006) - rosiglitazone
• Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia - This study is currently recruiting patients (Current: 23 Nov 2006) - Niacin,Fenofibrate
• Acipimox to Improve Hyperlipidemia and Insulin Sensitivity Associated With HIV - This study is no longer recruiting patients (Current: 23 Nov 2006) - Acipimox
• (Mol-SHARE) Molecular Study of Health Assessment and Risk in Ethnic Groups - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Resistance in Non-Alcoholic Steatohepatitis - This study is currently recruiting patients (Current: 23 Nov 2006) - rosiglitazone,fenofibrate
• Effect of Salicylate on Glucose Metabolism in Insulin Resistance States - This study is no longer recruiting patients (Current: 23 Nov 2006) - salicylate
• Insulin Resistance and Vessel Function After Meals: Does Early Intervention Make a Difference? - This study is currently recruiting patients (Current: 23 Nov 2006) - Nateglinide
• The Study of HIV Protease Inhibitors and Their Effects on Glucose Metabolism - This study is currently recruiting patients (Current: 23 Nov 2006) - HIV protease inhibitors (lopinavir/ritonavir, indinavir, amprenavir, and ritonavir)
• Diagnosis of Insulin Resistance: 13C-Glucose Breath Test Vs HOMA Index. - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• The Metabolic Effects of Almond Consumption in Adults With Pre-Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effects of Resistance and Aerobic Exercise on Cardiovascular Health - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Resistance in Severely Obese Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Influence of Rosiglitazone on the Diuretic Effect of Furosemide and Amiloride - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosiglitazone versus placebo,response (sodium excretion) to amiloride infusion,response (sodium excetion) to furosemide infusion
• Popular Diets, Metabolism, and CVD Risk - This study is currently recruiting patients (Current: 23 Nov 2006)
• Salsalate Therapy to Reduce Insulin Resistance and Cardiovascular Risk - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Salsalate therapy vs. placebo
• Ziprasidone for Improving Insulin Sensitivity in People With Schizophrenia Who Are at Risk for Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Ziprasidone
• Effectiveness of Aripiprazole for Improving Side Effects of Clozapine in the Treatment of People With Schizophrenia - This study is currently recruiting patients (Current: 23 Nov 2006) - Aripiprazole
• Effect of Rosiglitazone in Nondiabetic Patients With the Metabolic Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006) - Rosiglitazone
• Study of Improving Insulin Sensitivity by Electroacupuncture Therapy - This study has been completed (Current: 23 Nov 2006)
• Changes in Inflammatory State in Asian Americans Changing From Traditional Asian Diets to American Diet - a Pilot Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Regulation of Lipoprotein Metabolism in Obese Men - This study has been completed (Current: 23 Nov 2006) - Atorvastatin,Fish oils
• A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - INCB13739
• Dietary Fish Protein in Subjects With Insulin Resistance - This study has been completed (Current: 23 Nov 2006)
• Oatmeal and Insulin Resistance - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• ACTIV- Exercise Intervention in Healthy Young Men - This study is currently recruiting patients (Current: 23 Nov 2006)
• Weight Loss in Diabetic, Older Obese Adults - This study is currently recruiting patients (Current: 23 Nov 2006)
• Comparing the Effects of Two Diets on the Heart, Blood Vessels, and Cholesterol Levels in Individuals With Metabolic Syndrome - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study - This study is currently recruiting patients (Current: 23 Nov 2006) - Study drugs: Metformin and fenofibrate
• Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial - This study is currently recruiting patients (Current: 23 Nov 2006) - Telmisartan (Micardis®) vs. Placebo
• Behavioral Factors in Coronary Heart Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Genetic Determinants:Low HDL, High Triglycerides, Obesity - This study has been completed (Current: 23 Nov 2006)
• Partnership Programs to Reduce Ethnic Differences in the Risk of Cardiovascular Disease - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• 20 Year Changes in Fitness & Cardiovascular Disease Risk - Ancillary to CARDIA - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Effects of Tumor Necrosis Factor (TNF)-Alpha Antagonism in Patients With Metabolic Syndrome - This study has been completed (Current: 23 Nov 2006) - Etanercept
• Inflammatory Profiles of Children at High Risk for Atherosclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Exercise and Weight Loss for Improving Mobility in People Who Are Obese and Have Heart Problems - This study is currently recruiting patients (Current: 23 Nov 2006)
• STOP CAP: Pravastatin and Atorvastatin to Prevent Heart Disease in People With High Cholesterol Level, Diabetes or Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Atorvastatin,Pravastatin
• Pancreatic Islet Function, Insulin Sensitivity, and Chronic Complications in Pre-Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effect of Vegetable Oils for Use by the Snack Food Industry on Plasma Lipid Levels and Inflammatory Markers - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Potential Role for Adenosine in the Haemodynamic Effects of Free Fatty Acids - This study is currently recruiting patients (Current: 23 Nov 2006) - Intravenous infusion of Intralipid/heparin,Intravenous infusion of Glycerol/heparin
• Weight and Metabolic Effects of an Almond Enriched Hypocaloric, Low Fat Diet on Overweight and Obese Persons - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Effects of Aripiprazole on Patients With Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Aripiprazole
• Rosiglitazone Versus Placebo in Chronic Stable Angina - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Rosiglitazone
• Atherosclerosis Underlying Development Assessed by Intima-Media Thickness in Patients on Rimonabant (Auditor) - This study has been completed (Current: 23 Nov 2006) - Rimonabant
• Phase IV, 9 Weeks Comparison Between MICARDIS 80 mg and Amlodipine 10 mg on Biological PPAR Gamma Activities - This study is currently recruiting patients (Current: 23 Nov 2006) - MICARDIS,amlodipine
• Efficacy of Topiramate for Weight Loss in Subjects With Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - topiramate
• Comparison of Two Different Diets on Health Outcomes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Aspirin
• Collaborative Care for Heart Failure Patients With the Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• PROCLAIM: Study Examining Effects of Clopidogrel Compared to Placebo on Inflammation in Subjects With Metabolic Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006) - clopidogrel
• The Effect of Diet and Exercise in Heart Failure - This study is currently recruiting patients (Current: 23 Nov 2006)
• Health of Young European Families and Fish Consumption - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Examining the Link Between Trace Elements and Cardiovascular Disease Risk Factors in Young Adults - This study is no longer recruiting patients (Current: 23 Nov 2006)
• The Effects of Cilnidipine on Metabolic Syndrome Improvement - This study is currently recruiting patients (Current: 23 Nov 2006) - Cilnidipine
• A Mechanistic Study of the Effects of LY518674 on High-Density Lipoprotein Cholesterol (HDL-C) Metabolism - This study is currently recruiting patients (Current: 23 Nov 2006) - LY518674
• Effectiveness of Nigella Sativa (Kalonji) Seed in Dyslipidemia - This study is currently recruiting patients (Current: 23 Nov 2006) - Nigella sativa seed
• The Effects of Omega-3 Fatty Acids on Metabolic Syndrome - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Omega-3 fatty acids in the form of fish oil capsule
• Cardiovascular Disease Risk Factors in Chinese American Immigrants - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• ROMEO (ROsuvastatin in MEtabolic Syndrome With Obesity) - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosuvastatin,Atorvastatin
• Lifestyle Modification and Metformin Use in the Treatment of HIV - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Metformin
• Evaluation of Effect of Exercise on Prescription - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Leptin to Treat Severe Insulin Resistance - Pilot Study - This study has been completed (Current: 23 Nov 2006) - Leptin A-100
• Metformin in Assisted Reproduction - This study is currently recruiting patients (Current: 23 Nov 2006) - Metformin / Placebo treatment for 4 months
• Metabolism and Body Shape of Healthy Children and Children With Chronic Infections - This study has been completed (Current: 23 Nov 2006)
• Methods for Measuring Insulin Sensitivity - This study is currently recruiting patients (Current: 23 Nov 2006)
• Heart Disease Risk Factors in African Americans - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of the Effects of Vitamin C on Patients With Type 2 Diabetes - This study has been completed (Current: 23 Nov 2006) - Acetylcholine
• A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients - This study has been completed (Current: 23 Nov 2006) - Abacavir sulfate,Amprenavir,Lamivudine
• Leptin to Treat Lipodystrophy - This study has been completed (Current: 23 Nov 2006) - hu Leptin (A-100)
• Effects of Rosiglitazone on Blood Vessels in Patients With High Blood Pressure and High Cholesterol - This study has been completed (Current: 23 Nov 2006)
• A Study to Determine How and Why HIV-Infected Subjects on Anti-Viral Treatment Develop Lipodystrophy - This study has been completed (Current: 23 Nov 2006) - Nelfinavir mesylate,Stavudine,Lamivudine,Efavirenz
• Treatment of Nonalcoholic Steatohepatitis With Pioglitazone - This study has been completed (Current: 23 Nov 2006)
• Use of a Test That Evaluates How the Body Handles Insulin and Glucose - This study has been completed (Current: 23 Nov 2006)
• Endothelial Dysfunction as a Risk Factor in HIV Study - This study has been completed (Current: 23 Nov 2006) - Pravastatin,Gemfibrozil,Rosiglitazone
• Treating Nonalcoholic Steatohepatitis With Pioglitazone - This study is currently recruiting patients (Current: 23 Nov 2006) - Actos (Pioglitazone)
• Treating Nonalcoholic Steatohepatitis (NASH) With Metformin - This study is currently recruiting patients (Current: 23 Nov 2006) - Metformin
• Genetics and Clinical Characteristics of Bardet-Biedl Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Resistance Intervention After Stroke (IRIS) Trial - This study is currently recruiting patients (Current: 23 Nov 2006) - pioglitazone
• Effects of Dark Chocolate on Insulin Sensitivity in People With High Blood Pressure - This study is currently recruiting patients (Current: 23 Nov 2006)
• Thyroid and Glucose and Energy Metabolism - This study is currently recruiting patients (Current: 23 Nov 2006) - Liothyronine (T3),Levothyroxine (T4)
• Low Carbohydrate Diet Compared to Calorie and Fat Restricted Diet in Patients With Obesity and Type II Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese Children - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study to Examine Insulin Resistance During Growth Hormone Treatment for Short Stature Due to Low Birthweight - This study is currently recruiting patients (Current: 23 Nov 2006) - somatropin (rDNA)
• Study to Identify Markers of Insulin Resistance During Growth Hormone Treatment for Short Stature - This study is currently recruiting patients (Current: 23 Nov 2006) - somatropin (rDNA)
• Growth Hormone, Cardiovascular Risk, and Visceral Adiposity in Women - This study is currently recruiting patients (Current: 23 Nov 2006) - Nutropin AQ growth hormone
• Randomized, Placebo-Controlled Study of Leptin for the Treatment of HIV Lipodystrophy and Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - r-metHuLeptin
• Glycemic Index and CVD: a Crossover Feeding Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pioglitazone Treatment in Polycystic Ovary Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006) - Tablet Actos, 30mg/day
• The Effect of Metformin in Overweight Patients With Dysregulated Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006) - Tablet Metformin 500 mg
• Body Composition, Glucose Metabolism, Insulin Resistance and Gene Expression in Muscle Cells in Healthy Overweight Women - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Free Fatty Acids and Vascular Function in Subjects With Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - acipimox
• Orlistat (Xenical) in the Treatment of Overweight Patients With Nonalcoholic Steatohepatitis (NASH) - This study is currently recruiting patients (Current: 23 Nov 2006) - Orlistat (Xenical)
• Barriers to Treatment in Obese Adolescents - This study is currently recruiting patients (Current: 23 Nov 2006)
• Comparison of Oxidative Stress and Insulin Resistance Before and After Using Physioneal in Peritoneal Dialysis Patients - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Physioneal
• The Relation Between OSA and Metabolic Syndrome: Role of Oxidative Stress - This study is currently recruiting patients (Current: 23 Nov 2006)
• Obesity, Weight Loss, and Cardiovascular Disease Risk - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Resistance Associated With Chronic Hepatitis C (CHC) and the Effect of Antiviral Therapy - This study is currently recruiting patients (Current: 23 Nov 2006) - Pegasys; Copegus
• Pioglitazone in Hepatitis C - This study is currently recruiting patients (Current: 23 Nov 2006) - Pioglitazone
• Pharmacogenetic Profiling of Antipsychotics-Induced X-Syndrome and Diabetes (PAXD) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Polycystic Ovary Syndrome (PCOS) and Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006) - depot leuprolide plus estrogen/progestin replacement,pioglitazone
• Therapy With Infergen, Ribavirin, & Avandia in a Group of Insulin Resistant, Chronic Hepatitis C, Genotype 1 Patients Who Are Previous Relapsers or Nonresponders to Pegylated Interferon and Ribavirin - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Infergen,ribavirin,rosiglitazone
• Rosiglitazone-Induced Weight Gain - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosiglitazone
• Assessment of Changes in Abdominal Fat - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Study of the Safety and Effectiveness of Topiramate on Insulin Sensitivity in Overweight or Obese Patients With Type 2 Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006) - topiramate
• Glucose Optimisation With Angiotensin II Antagonist Losartan (GOAAL) - This study has been completed (Current: 23 Nov 2006) - Amlodipine 10 mg or Losartan 100 mg + Amlodipine 5 mg
• Effect of Cinnamon on Glucose and Lipid Levels in Non-Insulin Dependent Type 2 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006) - Cinnamon 500 mg capsule twice daily
• Metformin in Patients With Non-Alcoholic Fatty Liver Disease (NAFLD) - This study is currently recruiting patients (Current: 23 Nov 2006) - Metformin
• Fibre and Appetite Regulation Trial (FART) - This study has been completed (Current: 23 Nov 2006) - Low fibre breakfast cereal (puffed rice/cornflakes),High fibre cereal (All Bran/Bran Flakes)
• Natural History Study of Patients With Excess Androgen - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effect of 48 Hours Treatment With Natural Peptide-Hormone GLP-1 in Patients With Chronic Heart Failure. - This study is currently recruiting patients (Current: 23 Nov 2006) - glucagon-like-peptide-1 (GLP-1)
• Physical Activity, Insulin Resistance and Function of Fat Tissue in the Offspring of Patients With Type 2 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Assessing the Efficacy and Safety of Rosiglitazone Added to Standard Therapy for Hepatitis C Genotype 1 With Fatty Liver - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosiglitazone and Pegasys/Ribavirin
• Niacin, N-3 Fatty Acids and Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006) - omega-3 acid ethyl esters,niacin
• The Prevalence of Vitamin D Deficiency and Effects of Vitamin D Supplementation in HIV-1 Infected Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - colecalciferol
• Prevention of Weight Gain in Young Adults - This study has been completed (Current: 23 Nov 2006)
• Effect Of Rosiglitazone On Carotid Intima Media Thickness In Patients With Insulin Resistance Syndrome And/Or Type 2 Diabetes - This study has been completed (Current: 23 Nov 2006) - Rosiglitazone
• PUFA in the Treatment of NASH in Patients With Type 2 Diabetes Mellitus (PUFA) - This study is currently recruiting patients (Current: 23 Nov 2006) - PUFA,Placebo
• The Effect of Cinnamon Extract on Insulin Resistance Parameters in Polycystic Ovary Syndrome: A Pilot Study - This study has been completed (Current: 23 Nov 2006) - Oral Cinnamon Extract
• Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment - This study is no longer recruiting patients (Current: 23 Nov 2006) - Drug: Rosiglitazone
• The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers - This study is currently recruiting patients (Current: 23 Nov 2006) - Salsalate,Rofecoxib
• Cross-Sectional and Longitudinal Studies of "Pre-Diabetes" in the Pima Indians - This study is currently recruiting patients (Current: 23 Nov 2006)
• Exenatide and Metformin Therapy in Overweight Women With PCOS - This study is currently recruiting patients (Current: 23 Nov 2006) - metformin, exenatide or combined (metformin & exenatide )
• Omega-3 Fatty Acids for High Triglycerides in HIV-Infected Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ziprasidone for Clozapine- or Olanzapine-Associated Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006) - Ziprasidone
• A Placebo-Controlled, Cross-Over Trial of Aripiprazole - This study is currently recruiting patients (Current: 23 Nov 2006) - Aripiprazole(drug)
• Study to Determine the Effects of Human Growth Hormone and Pioglitazone in Overweight, Prediabetic Adults - This study has been completed (Current: 23 Nov 2006) - Recombinant human growth hormone; pioglitazone
• Adolescent Gastric by-Pass and Diabetic Precursors - This study is currently recruiting patients (Current: 23 Nov 2006)
• Combination of Pioglitazone and Leptin as Treatment for the HAART -Induced Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Leptin,Pioglitazone
• The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Testosterone Effects on Men With the Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Testosterone,Anastrozole,Goserelin
• Breast Cancer Lymphedema: Role of Insulin Resistance/FOXC2 - This study is currently recruiting patients (Current: 23 Nov 2006)
• Non-Invasive Evaluation of Hepatic Fibrosis in Patients With the Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Potential Association of a Common L-FABP Polymorphism With Lipid-Induced Hepatic Insulin Resistance - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Mechanism of Fatty Acid-Induced Impairment of Glucose-Stimulated Insulin Secretion - This study is currently recruiting patients (Current: 23 Nov 2006) - N-acetylcysteine, intralipid, heparin
• Bumetanide Vs. Furosemide in Heart Failure - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Furosemide,Bumetanide
• Safety and Effects of Ramipril Combined With Candesartan - This study has been completed (Current: 23 Nov 2006) - ramipril,candesartan
• Metabolic Syndrome and Insulin Resistance in Primary Aldosteronism - This study is currently recruiting patients (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Insulin Resistance

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Insulin Resistance:

• 20% Intralipid - Mechanisms of Insulin Resistance in Humans - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Abacavir sulfate - A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients - This study has been completed (Current: 23 Nov 2006)
• Acetylcholine - Study of the Effects of Vitamin C on Patients With Type 2 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Acipimox - Acipimox to Improve Hyperlipidemia and Insulin Sensitivity Associated With HIV - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Acipimox - Free Fatty Acids and Vascular Function in Subjects With Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Actos (Pioglitazone) - Treating Nonalcoholic Steatohepatitis With Pioglitazone - This study is currently recruiting patients (Current: 23 Nov 2006)
• Amlodipine 10 mg or Losartan 100 mg + Amlodipine 5 mg - Glucose Optimisation With Angiotensin II Antagonist Losartan (GOAAL) - This study has been completed (Current: 23 Nov 2006)
• Amlodipine - Phase IV, 9 Weeks Comparison Between MICARDIS 80 mg and Amlodipine 10 mg on Biological PPAR Gamma Activities - This study is currently recruiting patients (Current: 23 Nov 2006)
• Amprenavir - A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients - This study has been completed (Current: 23 Nov 2006)
• Anastrozole - Testosterone Effects on Men With the Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Aripiprazole(drug) - A Placebo-Controlled, Cross-Over Trial of Aripiprazole - This study is currently recruiting patients (Current: 23 Nov 2006)
• Aripiprazole - Effectiveness of Aripiprazole for Improving Side Effects of Clozapine in the Treatment of People With Schizophrenia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Aripiprazole - The Effects of Aripiprazole on Patients With Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Aspirin - Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Atenolol - A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overweight Patients With High Blood Pressure to Respond to Insulin - This study has been completed (Current: 23 Nov 2006)
• Atorvastatin - ARREST PAD (Peripheral Arterial Disease) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Atorvastatin - ROMEO (ROsuvastatin in MEtabolic Syndrome With Obesity) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Atorvastatin - Regulation of Lipoprotein Metabolism in Obese Men - This study has been completed (Current: 23 Nov 2006)
• Atorvastatin - Relation of Inflammation and Insulin Resistance to Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Atorvastatin - STOP CAP: Pravastatin and Atorvastatin to Prevent Heart Disease in People With High Cholesterol Level, Diabetes or Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Avandia administration for 6-12 weeks - Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy Syndrome - This study has been completed (Current: 23 Nov 2006)
• Avandia - Study In Patients With Insulin Resistance - This study has been completed (Current: 23 Nov 2006)
• Bumetanide - Bumetanide Vs. Furosemide in Heart Failure - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Candesartan - Safety and Effects of Ramipril Combined With Candesartan - This study has been completed (Current: 23 Nov 2006)
• Chromium piccolinate - Use of a Nutritional Supplement to Treat Diabetic Symptoms in HIV-Infected Adults - This study is currently recruiting patients (Current: 23 Nov 2006)
• Chromium picolinate - Chromium Picolinate for the Treatment of Metabolic Syndrome - This study has been completed (Current: 23 Nov 2006)
• Cilnidipine - The Effects of Cilnidipine on Metabolic Syndrome Improvement - This study is currently recruiting patients (Current: 23 Nov 2006)
• Cinnamon 500 mg capsule twice daily - Effect of Cinnamon on Glucose and Lipid Levels in Non-Insulin Dependent Type 2 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Clopidogrel - PROCLAIM: Study Examining Effects of Clopidogrel Compared to Placebo on Inflammation in Subjects With Metabolic Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Colecalciferol - The Prevalence of Vitamin D Deficiency and Effects of Vitamin D Supplementation in HIV-1 Infected Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• DHEA - Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans - This study has been completed (Current: 23 Nov 2006)
• Depot Leuprolide Plus Estrogen/Progestin Replacement - Polycystic Ovary Syndrome (PCOS) and Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
• Dietary supplement for weight loss - Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Drug: Rosiglitazone - Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Efavirenz - A Study to Determine How and Why HIV-Infected Subjects on Anti-Viral Treatment Develop Lipodystrophy - This study has been completed (Current: 23 Nov 2006)
• Etanercept - Effects of Tumor Necrosis Factor (TNF)-Alpha Antagonism in Patients With Metabolic Syndrome - This study has been completed (Current: 23 Nov 2006)
• Fenofibrate - Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Fenofibrate - Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Fenofibrate - Insulin Resistance in Non-Alcoholic Steatohepatitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Fenofibrate - Study of Niacin and Rosiglitazone in Dysmetabolic Dyslipidemia - This study has been completed (Current: 23 Nov 2006)
• Fenofibrate - Substrate Cycling in Energy Metabolism - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Fish oils - Regulation of Lipoprotein Metabolism in Obese Men - This study has been completed (Current: 23 Nov 2006)
• Furosemide - Bumetanide Vs. Furosemide in Heart Failure - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Gemfibrozil - Endothelial Dysfunction as a Risk Factor in HIV Study - This study has been completed (Current: 23 Nov 2006)
• Glucagon-Like-Peptide-1 (Glp-1) - Effect of 48 Hours Treatment With Natural Peptide-Hormone GLP-1 in Patients With Chronic Heart Failure. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Glucosamine Hydrochloride - Effects of Oral Glucosamine on Insulin and Blood Vessel Activity in Normal and Obese People - This study is currently recruiting patients (Current: 23 Nov 2006)
• Goserelin - Testosterone Effects on Men With the Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• HIV protease inhibitors (lopinavir/ritonavir, indinavir, amprenavir, and ritonavir) - The Study of HIV Protease Inhibitors and Their Effects on Glucose Metabolism - This study is currently recruiting patients (Current: 23 Nov 2006)
• High fibre cereal (All Bran/Bran Flakes) - Fibre and Appetite Regulation Trial (FART) - This study has been completed (Current: 23 Nov 2006)
• Hu Leptin (A-100) - Effect of Leptin Therapy in the Treatment of Severe Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006)
• Hu Leptin (A-100) - Leptin to Treat Lipodystrophy - This study has been completed (Current: 23 Nov 2006)
• Hypoglycemic Agents - Bypass Angioplasty Revascularization Investigation in Type 2 Diabetics (BARI 2D) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• INCB13739 - A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Infergen - Therapy With Infergen, Ribavirin, & Avandia in a Group of Insulin Resistant, Chronic Hepatitis C, Genotype 1 Patients Who Are Previous Relapsers or Nonresponders to Pegylated Interferon and Ribavirin - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Insulin-Like Growth Factor I - Study of Recombinant Human Insulin-Like Growth Factor I in Patients With Severe Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006)
• Intralipid - Determining the Responsiveness of Intestinal Lipoprotein Production to an Elevation of Plasma Free Fatty Acids - This study is currently recruiting patients (Current: 23 Nov 2006)
• Intravenous infusion of Glycerol/heparin - The Potential Role for Adenosine in the Haemodynamic Effects of Free Fatty Acids - This study is currently recruiting patients (Current: 23 Nov 2006)
• Intravenous infusion of Intralipid/heparin - The Potential Role for Adenosine in the Haemodynamic Effects of Free Fatty Acids - This study is currently recruiting patients (Current: 23 Nov 2006)
• LY518674 - A Mechanistic Study of the Effects of LY518674 on High-Density Lipoprotein Cholesterol (HDL-C) Metabolism - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lamivudine - A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients - This study has been completed (Current: 23 Nov 2006)
• Lamivudine - A Study to Determine How and Why HIV-Infected Subjects on Anti-Viral Treatment Develop Lipodystrophy - This study has been completed (Current: 23 Nov 2006)
• Leptin A-100 - Leptin to Treat Severe Insulin Resistance - Pilot Study - This study has been completed (Current: 23 Nov 2006)
• Leptin - Combination of Pioglitazone and Leptin as Treatment for the HAART -Induced Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Leucine, Glycerol - Determining the Responsiveness of Intestinal Lipoprotein Production to an Elevation of Plasma Free Fatty Acids - This study is currently recruiting patients (Current: 23 Nov 2006)
• Leuprolide Acetate - Insulin Resistance and Testosterone in Women - This study is currently recruiting patients (Current: 23 Nov 2006)
• Levothyroxine (T4) - Thyroid and Glucose and Energy Metabolism - This study is currently recruiting patients (Current: 23 Nov 2006)
• Liothyronine (T3) - Thyroid and Glucose and Energy Metabolism - This study is currently recruiting patients (Current: 23 Nov 2006)
• Losartan potassium - A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overweight Patients With High Blood Pressure to Respond to Insulin - This study has been completed (Current: 23 Nov 2006)
• Losartan - Treating the Endothelium to Restore Insulin Sensitivity - This study is currently recruiting patients (Current: 23 Nov 2006)
• Low fibre breakfast cereal (puffed rice/cornflakes) - Fibre and Appetite Regulation Trial (FART) - This study has been completed (Current: 23 Nov 2006)
• MICARDIS® (telmisartan) - The Primary Objective of This Study is to Determine Whether MICARDIS Improves Insulin Sensitivity in Overweight or Obese, Non-Diabetic, Normotensive Subjects. - This study has been completed (Current: 23 Nov 2006)
• MICARDIS - Phase IV, 9 Weeks Comparison Between MICARDIS 80 mg and Amlodipine 10 mg on Biological PPAR Gamma Activities - This study is currently recruiting patients (Current: 23 Nov 2006)
• Metformin / Placebo treatment for 4 months - Metformin in Assisted Reproduction - This study is currently recruiting patients (Current: 23 Nov 2006)
• Metformin, Exenatide Or Combined (Metformin &Amp; Exenatide ) - Exenatide and Metformin Therapy in Overweight Women With PCOS - This study is currently recruiting patients (Current: 23 Nov 2006)
• Metformin - A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes) - This study has been completed (Current: 23 Nov 2006)
• Metformin - Insulin Resistance and Testosterone in Women - This study is currently recruiting patients (Current: 23 Nov 2006)
• Metformin - Lifestyle Modification and Metformin Use in the Treatment of HIV - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Metformin - Metformin in Patients With Non-Alcoholic Fatty Liver Disease (NAFLD) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Metformin - Pegylated-Interferon and Ribavirin Plus Metformin in the Treatment of Chronic HCV Infection and Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006)
• Metformin - The Effects of Calorie Restriction With or Without Metformin on Weight and Insulin Resistance - This study has been completed (Current: 23 Nov 2006)
• Metformin - Treating Nonalcoholic Steatohepatitis (NASH) With Metformin - This study is currently recruiting patients (Current: 23 Nov 2006)
• N-acetylcysteine, intralipid, heparin - Mechanism of Fatty Acid-Induced Impairment of Glucose-Stimulated Insulin Secretion - This study is currently recruiting patients (Current: 23 Nov 2006)
• Nateglinide - Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Nateglinide - Insulin Resistance and Vessel Function After Meals: Does Early Intervention Make a Difference? - This study is currently recruiting patients (Current: 23 Nov 2006)
• Nelfinavir mesylate - A Study to Determine How and Why HIV-Infected Subjects on Anti-Viral Treatment Develop Lipodystrophy - This study has been completed (Current: 23 Nov 2006)
• Niacin - Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Niacin - Niacin, N-3 Fatty Acids and Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006)
• Niacin - Study of Niacin and Rosiglitazone in Dysmetabolic Dyslipidemia - This study has been completed (Current: 23 Nov 2006)
• Nigella sativa seed - Effectiveness of Nigella Sativa (Kalonji) Seed in Dyslipidemia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Nutropin AQ growth hormone - Growth Hormone, Cardiovascular Risk, and Visceral Adiposity in Women - This study is currently recruiting patients (Current: 23 Nov 2006)
• Olmesartan medoxomil - A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overweight Patients With High Blood Pressure to Respond to Insulin - This study has been completed (Current: 23 Nov 2006)
• Omega-3 Acid Ethyl Esters - Niacin, N-3 Fatty Acids and Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006)
• Omega-3 fatty acids in the form of fish oil capsule - The Effects of Omega-3 Fatty Acids on Metabolic Syndrome - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Oral Cinnamon Extract - The Effect of Cinnamon Extract on Insulin Resistance Parameters in Polycystic Ovary Syndrome: A Pilot Study - This study has been completed (Current: 23 Nov 2006)
• Orlistat (Xenical) - Orlistat (Xenical) in the Treatment of Overweight Patients With Nonalcoholic Steatohepatitis (NASH) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ortho Tri Cyclen - Oral Contraceptives in the Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• PUFA - PUFA in the Treatment of NASH in Patients With Type 2 Diabetes Mellitus (PUFA) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Panax Ginseng - Efficacy Study of Panax Ginseng to Boost Antipsychotics Effects in Schizophrenia - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pegasys; Copegus. - Insulin Resistance Associated With Chronic Hepatitis C (CHC) and the Effect of Antiviral Therapy - This study is currently recruiting patients (Current: 23 Nov 2006)
• Physioneal - Comparison of Oxidative Stress and Insulin Resistance Before and After Using Physioneal in Peritoneal Dialysis Patients - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Pioglitazone - A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes) - This study has been completed (Current: 23 Nov 2006)
• Pioglitazone - Combination of Pioglitazone and Leptin as Treatment for the HAART -Induced Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pioglitazone - Insulin Resistance Intervention After Stroke (IRIS) Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pioglitazone - Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pioglitazone - Pioglitazone as a Treatment for Lipid and Glucose Abnormalities In Patients With Schizophrenia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pioglitazone - Pioglitazone in Hepatitis C - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pioglitazone - Polycystic Ovary Syndrome (PCOS) and Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
• Placebo - Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Placebo - PUFA in the Treatment of NASH in Patients With Type 2 Diabetes Mellitus (PUFA) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pravastatin - Endothelial Dysfunction as a Risk Factor in HIV Study - This study has been completed (Current: 23 Nov 2006)
• Pravastatin - STOP CAP: Pravastatin and Atorvastatin to Prevent Heart Disease in People With High Cholesterol Level, Diabetes or Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• R-Methuleptin - Randomized, Placebo-Controlled Study of Leptin for the Treatment of HIV Lipodystrophy and Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ramipril - Safety and Effects of Ramipril Combined With Candesartan - This study has been completed (Current: 23 Nov 2006)
• Recombinant Human Growth Hormone - Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006)
• Recombinant human growth hormone; pioglitazone - Study to Determine the Effects of Human Growth Hormone and Pioglitazone in Overweight, Prediabetic Adults - This study has been completed (Current: 23 Nov 2006)
• Response (Sodium Excetion) To Furosemide Infusion - The Influence of Rosiglitazone on the Diuretic Effect of Furosemide and Amiloride - This study is currently recruiting patients (Current: 23 Nov 2006)
• Response (Sodium Excretion) To Amiloride Infusion - The Influence of Rosiglitazone on the Diuretic Effect of Furosemide and Amiloride - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ribavirin - Therapy With Infergen, Ribavirin, & Avandia in a Group of Insulin Resistant, Chronic Hepatitis C, Genotype 1 Patients Who Are Previous Relapsers or Nonresponders to Pegylated Interferon and Ribavirin - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Rimonabant - Atherosclerosis Underlying Development Assessed by Intima-Media Thickness in Patients on Rimonabant (Auditor) - This study has been completed (Current: 23 Nov 2006)
• Rofecoxib - The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone (Avandia) - Rosiglitazone and Exercise Training: Effects on HIV-Infected People With Insulin Resistance, Hypertriglyceridemia, and Adipose Tissue Maldistribution - This study has been completed (Current: 23 Nov 2006)
• Rosiglitazone and Pegasys/Ribavirin - Assessing the Efficacy and Safety of Rosiglitazone Added to Standard Therapy for Hepatitis C Genotype 1 With Fatty Liver - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone insulin sensitizing agent - Diet, Exercise &/or Rosiglitazone for HIV-Associated Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone versus placebo - The Influence of Rosiglitazone on the Diuretic Effect of Furosemide and Amiloride - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes) - This study has been completed (Current: 23 Nov 2006)
• Rosiglitazone - ARREST PAD (Peripheral Arterial Disease) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Effect Of Rosiglitazone On Carotid Intima Media Thickness In Patients With Insulin Resistance Syndrome And/Or Type 2 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Rosiglitazone - Effect of Rosiglitazone in Nondiabetic Patients With the Metabolic Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Endothelial Dysfunction as a Risk Factor in HIV Study - This study has been completed (Current: 23 Nov 2006)
• Rosiglitazone - Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Insulin Resistance in Non-Alcoholic Steatohepatitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Insulin Resistance in Patients With Mood Disorder - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Relation of Inflammation and Insulin Resistance to Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Rosiglitazone Versus Placebo in Chronic Stable Angina - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Rosiglitazone - Rosiglitazone-Induced Weight Gain - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Study of Niacin and Rosiglitazone in Dysmetabolic Dyslipidemia - This study has been completed (Current: 23 Nov 2006)
• Rosiglitazone - Therapy With Infergen, Ribavirin, & Avandia in a Group of Insulin Resistant, Chronic Hepatitis C, Genotype 1 Patients Who Are Previous Relapsers or Nonresponders to Pegylated Interferon and Ribavirin - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Rosuvastatin - ROMEO (ROsuvastatin in MEtabolic Syndrome With Obesity) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Salicylate - Effect of Salicylate on Glucose Metabolism in Insulin Resistance States - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Salicylate - Mechanisms of Insulin Resistance in Humans - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Salsalate therapy vs. placebo - Salsalate Therapy to Reduce Insulin Resistance and Cardiovascular Risk - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Salsalate - The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers - This study is currently recruiting patients (Current: 23 Nov 2006)
• Somatropin (Rdna) - Study to Examine Insulin Resistance During Growth Hormone Treatment for Short Stature Due to Low Birthweight - This study is currently recruiting patients (Current: 23 Nov 2006)
• Somatropin (Rdna) - Study to Identify Markers of Insulin Resistance During Growth Hormone Treatment for Short Stature - This study is currently recruiting patients (Current: 23 Nov 2006)
• Stavudine - A Study to Determine How and Why HIV-Infected Subjects on Anti-Viral Treatment Develop Lipodystrophy - This study has been completed (Current: 23 Nov 2006)
• Study drugs: Metformin and fenofibrate - The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tablet Actos, 30mg/day - Pioglitazone Treatment in Polycystic Ovary Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Tablet Metformin 500 mg - The Effect of Metformin in Overweight Patients With Dysregulated Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Telmisartan (Micardis®) vs. Placebo - Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• Telmisartan - Treatment of Insulin Resistance in Hypertensive, Obese Adolescents - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Testosterone - Testosterone Effects on Men With the Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Thiazolidinedione - Integrating the Genetic and Metabolic Faces of Obesity - This study is currently recruiting patients (Current: 23 Nov 2006)
• Topical testosterone (Androgel) 10 g/day - Investigator Initiated Study of the Effects of Androgen Therapy on Carbohydrate and Lipid Metabolism In Elderly Men - This study is currently recruiting patients (Current: 23 Nov 2006)
• Topiramate - A Study of the Safety and Effectiveness of Topiramate on Insulin Sensitivity in Overweight or Obese Patients With Type 2 Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Topiramate - Efficacy of Topiramate for Weight Loss in Subjects With Metabolic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
• Triflusal (DCI) - Efficacy Pilot Study of Triflusal in the Attenuation of Insulin Resistance in Human Obesity - This study has been completed (Current: 23 Nov 2006)
• Ziprasidone - Ziprasidone for Clozapine- or Olanzapine-Associated Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ziprasidone - Ziprasidone for Improving Insulin Sensitivity in People With Schizophrenia Who Are at Risk for Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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