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Diseases » Interstitial lung disease » Clinical Trials

Clinical Trials for Interstitial lung disease

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Interstitial lung disease is grouped into the following categories:-

View by trial name

View by drugs used in Interstitial lung disease clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Interstitial lung disease:

Database of Interstitial Lung Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
Open-Label Study With Bosentan in Interstitial Lung Disease - This study is no longer recruiting patients (Current: 23 Nov 2006) - bosentan
Safety and Accuracy of Alveoscopy in Interstitial Lung Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
Epidemiology of Interstitial Lung Disease - This study has been completed (Current: 23 Nov 2006)
Idiopathic Pulmonary Fibrosis: a Case-Control Study - This study has been completed (Current: 23 Nov 2006)
Idiopathic Pulmonary Fibrosis--Pathogenesis and Staging - SCOR in Occupational and Immunological Lung Diseases - This study has been completed (Current: 23 Nov 2006)
Linkage Study in Familial Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006)
Popcorn Lung: the Discovery of a New Disease - This study has been completed (Current: 23 Nov 2006)
UPMC Simmons Center for Interstitial Lung Disease Research Registry - This study is currently recruiting patients (Current: 23 Nov 2006)
Can We Reduce Hospital Attendance Without Compromising Care by the Use of Telephone Consultation - This study is currently recruiting patients (Current: 23 Nov 2006)
Pulmonary Rehabilitation in Interstitial Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
Blood Collection From Individuals With Lung Disease for Genetic Studies - This study is currently recruiting patients (Current: 23 Nov 2006)
Lung Disease Associated With Rheumatoid Arthritis - This study is currently recruiting patients (Current: 23 Nov 2006)
Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis - This study is currently recruiting patients (Current: 23 Nov 2006)
Efficacy and Safety of Oral Bosentan in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - bosentan
Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study is currently recruiting patients (Current: 23 Nov 2006) - GC1008, Human Anti-Transforming Growth Factor-b 1, 2, 3 mAb
Gleevec Idiopathic Pulmonary Fibrosis (IPF) Study - This study has been completed (Current: 23 Nov 2006) - Imatinib Mesylate (Gleevec)
BUILD 3: Bosentan Use in Interstitial Lung Disease - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - bosentan
Diffuse Fibrotic Lung Disease - This study has been completed (Current: 23 Nov 2006) - prednisone,cyclophosphamide,dapsone
Treatment of Wegener's Granulomatosis With Cyclophosphamide - This study has been completed (Current: 23 Nov 2006)
Steroids and Methotrexate to Treat Systemic Vasculitis - This study has been completed (Current: 23 Nov 2006)
Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
Cyclophosphamide and Prednisone Followed by Methotrexate To Treat Vasculitides - This study has been completed (Current: 23 Nov 2006)
Diagnostic Effectiveness of Virtual Bronchoscopy - This study has been completed (Current: 23 Nov 2006)
Analysis of Bronchial Tissue and Fluid in Patients With Wegener's Granulomatosis - This study has been completed (Current: 23 Nov 2006)
Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone (Deskar),Pirfenidone
Segmental Bronchoalveolar Lavage - This study is currently recruiting patients (Current: 23 Nov 2006)
Assessment of Lung Inflammation in Patients With Atopic Asthma Using Positron Emission Tomography - This study has been completed (Current: 23 Nov 2006)
Phase I Trial of Recombinant Human Interleukin-10 (SCH 52000) in Patients With Wegener's Granulomatosis - This study has been completed (Current: 23 Nov 2006)
Mycophenolate Mofetil to Treat Wegener's Granulomatosis and Related Vascular Inflammatory Conditions - This study has been completed (Current: 23 Nov 2006) - Mycophenolate Mofetil
Treatment of Pulmonary Sarcoidosis With Pentoxifylline - This study has been completed (Current: 23 Nov 2006)
Specimen Collection for Individuals With Lung Disease Associated With Rheumatoid Arthritis - This study is currently recruiting patients (Current: 23 Nov 2006)
Etanercept to Treat Wegener's Granulomatosis - This study has been completed (Current: 23 Nov 2006) - Etanercept
Scleroderma Lung Study - This study has been completed (Current: 23 Nov 2006) - cyclophosphamide,azathioprine
Comparison of Treatments to Maintain Disease Remission in Patients With Wegener's Granulomatosis and Related Vasculitis Syndromes - This study has been completed (Current: 23 Nov 2006) - Mycophenolate Mofetil
Etanercept for Wegener's Granulomatosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Etanercept
Specialized Center of Research in Occupational and Immunologic Lung Disease - This study has been completed (Current: 23 Nov 2006)
Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases - This study is no longer recruiting patients (Current: 23 Nov 2006) - anti-thymocyte globulin,cyclophosphamide,cyclosporine,filgrastim,methylprednisolone,prednisone
Umbilical Cord Blood and Placental Blood Transplantation in Treating Patients With Hematologic Cancer or Aplastic Anemia - This study is currently recruiting patients (Current: 23 Nov 2006)
Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer - This study is currently recruiting patients (Current: 23 Nov 2006)
Pirfenidone in Treating Patients With Fibrosis Caused by Radiation Therapy for Cancer - This study has been suspended (Current: 23 Nov 2006) - pirfenidone
Etanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation - This study has been completed (Current: 23 Nov 2006) - etanercept
Daclizumab to Treat Wegener's Granulomatosis - This study has been completed (Current: 23 Nov 2006) - Daclizumab
IH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy for Early Breast Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - IH636 grape seed proanthocyanidin extract
A Study of the Safety and Efficacy Interferon-Gamma 1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006) - Interferon-gamma 1b
A Study of the Safety and Clinical Effects of Interferon Gamma-1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006) - Interferon-gamma 1b
Treatment of Resistant Langerhans Cell Histiocytosis With ENBREL - This study is no longer recruiting patients (Current: 23 Nov 2006) - Etanercept
A Randomized, Double-Blind, Three-Arm, Phase 3b Study Comparing the Safety and Efficacy of Interferon Gamma-1b With Azathioprine, and Azathioprine Alone in Patients With IPF Receiving Prednisone - This study has been terminated (Current: 23 Nov 2006) - interferon-gamma 1b,azathioprine
An Open-Label Study of the Safety and Efficacy of Subcutaneous Recombinant Interferon-Gamma 1b (IFN-Gamma 1b) in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006) - interferon-gamma 1b
Study Evaluating the Safety and Efficacy of Etanercept in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Etanercept
Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma - This study is no longer recruiting patients (Current: 23 Nov 2006) - Bosentan
An Open Label Pilot Study Examining the Use of Rituximab in Patients With Wegener's Granulomatosis Who Have Experienced Disease Relapse on Standard Therapies - This study has been completed (Current: 23 Nov 2006) - Rituximab
Safety and Tolerability Study of FG-3019 in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006) - FG-3019
The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Interferon gamma-1b ("Actimmune")
An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF - This study is no longer recruiting patients (Current: 23 Nov 2006) - Interferon gamma-1b
Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Women Who Have Undergone Radiation Therapy for Early Breast Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - hyperbaric oxygen
Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy - This study is currently recruiting patients (Current: 23 Nov 2006) - captopril
Pirfenidone for the Treatment of Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis (PF/IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Pirfenidone
Specimen Procurement From People With Hereditary Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases - This study is currently recruiting patients (Current: 23 Nov 2006) - anti-thymocyte globulin,busulfan,cyclophosphamide,cyclosporine,fludarabine phosphate,melphalan,methylprednisolone
Mycophenolate Mofetil for Treatment of Relapses of Wegener's Disease or Microscopic Polyangiitis (MPA) - This study is currently recruiting patients (Current: 23 Nov 2006) - mycophenolate mofetil
Rituximab for the Treatment of Wegener's Granulomatosis and Microscopic Polyangiitis - This study is currently recruiting patients (Current: 23 Nov 2006) - Rituximab,Cyclophosphamide,Azathioprine,Methylprednisolone (or other glucocorticoid),Prednisone
Inhaled Iloprost in Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Iloprost Inhalation Solution (Ventavis)
Beryllium Infliximab Study: Clinical Interventional Trial - This study is currently recruiting patients (Current: 23 Nov 2006) - Infliximab
Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation - This study is currently recruiting patients (Current: 23 Nov 2006)
Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol. - This study has been completed (Current: 23 Nov 2006) - Alendronate versus alfacalcidol (1-alpha OH vitamin D)
Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant - This study is currently recruiting patients (Current: 23 Nov 2006) - Etanercept
Risk Factors of Radiation Pneumonitis - This study is currently recruiting patients (Current: 23 Nov 2006)
Treatment of Idiopathic Pulmonary Fibrosis With Thalidomide - This study is currently recruiting patients (Current: 23 Nov 2006) - Thalidomide
T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic Disorders - This study is currently recruiting patients (Current: 23 Nov 2006) - busulfan, cyclophosphamide, and antithymocyte globulin (ATG)
Stem Cell Transplant for Immunologic or Histiocytic Disorders - This study is currently recruiting patients (Current: 23 Nov 2006) - Fludarabine,melphalan,ATG
Prospective Evaluations of Infectious Complication in Lung Transplant Recipients - This study is currently recruiting patients (Current: 23 Nov 2006)
Safety Study of Tetrathiomolybdate in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006) - Tetrathiomolybdate
Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study - This study is currently recruiting patients (Current: 23 Nov 2006) - minocycline
Evaluation of Patients With Idiopathic Pulmonary Fibrosis (IPF) Through an IPF Registry - This study is currently recruiting patients (Current: 23 Nov 2006)
A Pilot Study of Aerosol Interferon-Gamma Treatment in Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006) - Aerosol Interferon-gamma treatment
Microarray Analysis of Gene Expression in IPF - This study is currently recruiting patients (Current: 23 Nov 2006)
Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF) - This study is currently recruiting patients (Current: 23 Nov 2006)
Mycophenolate for Pulmonary Sarcoidosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Mycophenolate
Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - zileuton,azathioprine/prednisone
Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis - This study is currently recruiting patients (Current: 23 Nov 2006) - leucovorin calcium,methotrexate,prednisolone,vinblastine
Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
RATTRAP: Infliximab Versus Rituximab in Systemic Necrotizing Vasculitides - This study is currently recruiting patients (Current: 23 Nov 2006) - Infliximab,Rituximab
Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years - This study is currently recruiting patients (Current: 23 Nov 2006) - Corticosteroids (prednisone, methylprednisolone),Cyclophosphamide,Azathioprine,Mycophenolate mofetil
Determining Disease Activity Biomarkers in Individuals With Wegener's Granulomatosis and Microscopic Polyangiitis - This study is currently recruiting patients (Current: 23 Nov 2006)
Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension - This study is currently recruiting patients (Current: 23 Nov 2006) - Sildenafil (50 mg)
Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - sildenafil
Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
Use of Erythromycin in Mustard-Induced Bronchiolitis - This study has been completed (Current: 23 Nov 2006) - Erythromycin
Genomic and Proteomic Analysis of Disease Progression in IPF - This study is currently recruiting patients (Current: 23 Nov 2006)
Dry Powder Inhalation of Cyclosporine A in Lung Transplant Patients With Bronchiolitis Obliterans Syndrome - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Cyclosporine A dry powder inhalation (Drug)
Use of Clarithromycin in Mustard-Induced Bronchiolitis - This study has been completed (Current: 23 Nov 2006) - Clarithromycin
Dose Determination Safety and Activity Study of Inhaled NX1011 to Treat Pulmonary Arterial Hypertension - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - NX1011

Drugs used in Clinical Trials for Interstitial lung disease

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Interstitial lung disease: