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Causes of Intestinal Conditions

Intestinal Conditions Causes: Book Excerpts

Intestinal Conditions as a symptom:

Conditions listing Intestinal Conditions as a symptom may also be potential underlying causes of Intestinal Conditions. Our database lists the following as having Intestinal Conditions as a symptom of that condition:

Medical news summaries relating to Intestinal Conditions:

The following medical news items are relevant to causes of Intestinal Conditions:

Related information on causes of Intestinal Conditions:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Intestinal Conditions may be found in:

Causes of Intestinal Conditions: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Intestinal Conditions.

Constipation: Differential Diagnosis
(In a Page: Signs and Symptoms)

  • Medications
    –Narcotic analgesics
    –Antihypertensives (e.g., calcium channel blockers)
    –Tricyclic antidepressants
    –Aluminum hydroxide in antacids
    –Iron supplements
  • Inadequate dietary fiber or liquid intake
  • Neurological dysfunction
    –Diabetes mellitus
    –Multiple sclerosis
    –Hirschsprung's disease
  • Mechanical difficulties
    –Colorectal cancer
    –Hernia
    –Diverticulitis
    –Inflammatory bowel syndrome
    –Adhesion
    –Stricture
    –Torsion
    –Volvulus
  • Metabolic and endocrine
    –Hypothyroidism
    –Hypercalcemia
    –Hypokalemia
  • Chronic laxative abuse

» READ BOOK EXCERPT ONLINE »

Source: In a Page: Signs and Symptoms, 2004

Constipation: Differential Diagnosis
(In A Page: Pediatric Signs and Symptoms)

  • Functional constipation
    –By far the most common etiology
    –Rome II criteria define chronic functional constipation in infants and young children as at least 2 weeks of scybalous, pebble-like, hard stools for the majority of stools, or firm stools two or fewer times per week
    –Presents with stool-withholding behavior
    –Often due to inadequate fluid/fiber intake
  • Drugs: Antacids (with aluminium and calcium), anticholinergics, antidepressants, bismuth, calcium antagonists, cough suppressants, opioid analgesics, phenobarbitol
  • Irritable bowel syndrome
    • Endocrine disorders
      –Hypercalcemia
      –Hypothyroidism
      –Hyperparathyroidism
      –Pregnancy
      –Reduction of steroid hormones in luteal and follicular phases of menstrual cycle
    • Hirschsprung disease
      –1/5,000 births, male to female ratio 4:1
      –94% do not pass meconium within 24 hours of birth
      –61% diagnosed by 12 months of life
    • Neurologic disease
      –Myelomeningoce
      –Hypotonia (e.g., Down, myopathies, prune-belly syndrome)
      –Cerebral palsy
  • Celiac disease
  • Cystic fibrosis
  • Inflammatory bowel disease
  • Lead toxicity
  • Structural abnormalities
    –Anal disorders (imperforate anus, anteriorly displaced anus, perianal fissures, strep infection, anal stenosis)
    –Colonic strictures (primary or secondary)
    –Pelvic masses (sacral teratoma)
  • Infectious disease
    –Infantile botulism
    –Chagas disease
  • Metabolic disorders
    –Uremia
    –Hypokalemia
    –Amyloid neuropathy
  • Ogilvie syndrome

» READ BOOK EXCERPT ONLINE »

Source: In A Page: Pediatric Signs and Symptoms, 2007

Constipation: Medical causes
(Handbook of Signs & Symptoms (Third Edition))

Anal fissure.

 A crack or laceration in the lining of the anal wall can cause acute constipation, usually due to the patient's fear of the severe tearing or burning pain associated with bowel movements. He may notice a few drops of blood streaking toilet tissue or his underwear.

Anorectal abscess.

 In anorectal abscess, constipation occurs together with severe, throbbing, localized pain and tenderness at the abscess site. The patient may also have localized inflammation, swelling, and purulent drainage and may complain of fever and malaise.

Cirrhosis.

In the early stages of cirrhosis, the patient experiences constipation along with nausea and vomiting and a dull pain in the right upper quadrant. Other early findings include indigestion, anorexia, fatigue, malaise, flatulence, hepatomegaly and, possibly, splenomegaly and diarrhea.

Diabetic neuropathy.

Diabetic neuropathy produces episodic constipation or diarrhea. Other signs and symptoms include dysphagia, orthostatic hypotension, syncope, and painless bladder distention with overflow incontinence. A male patient may also experience impotence and retrograde ejaculation.

Diverticulitis.

 In diverticulitis, constipation or diarrhea occurs with left lower quadrant pain and tenderness and possibly a palpable, tender, firm, fixed abdominal mass. The patient may develop mild nausea, flatulence, or a low-grade fever.

Hemorrhoids.

Thrombosed hemorrhoids cause constipation as the patient tries to avoid the severe pain of defecation. The hemorrhoids may bleed during defecation.

Hepatic porphyria.

 Abdominal pain, which may be severe, colicky, localized, or generalized, precedes constipation in hepatic porphyria. The patient may also have a fever, sinus tachycardia, labile hypertension, excessive diaphoresis, severe vomiting, photophobia, urine retention, nervousness or restlessness, disorientation and, possibly, visual hallucinations. Deep tendon reflexes may be diminished or absent. He may also have skin lesions causing itching, burning, erythema, altered pigmentation, and edema in areas exposed to light. Severe hepatic porphyria can produce delirium, coma, seizures, paraplegia, or complete flaccid quadriplegia.

Hypercalcemia.

With hypercalcemia, constipation usually occurs along with anorexia, nausea, vomiting, polyuria, and polydipsia. The patient may also display arrhythmias, bone pain, muscle weakness and atrophy, hypoactive deep tendon reflexes, and personality changes.

Hypothyroidism.

Constipation occurs early and insidiously in patients with hypothyroidism, in addition to fatigue, sensitivity to cold, anorexia with weight gain, menorrhagia in women, decreased memory, hearing impairment, muscle cramps, and paresthesia.

Intestinal obstruction.

Constipation associated with an intestinal obstruction varies in severity and onset, depending on the location and extent of the obstruction. With partial obstruction, constipation may alternate with leakage of liquid stools. With complete obstruction, obstipation may occur. Constipation can be the earliest sign of partial colon obstruction, but it usually occurs later if the level of the obstruction is more proximal. Associated findings include episodes of colicky abdominal pain, abdominal distention, nausea, or vomiting. The patient may also develop hyperactive bowel sounds, visible peristaltic waves, a palpable abdominal mass, and abdominal tenderness.

Irritable bowel syndrome (IBS).

IBS commonly produces chronic constipation, although some patients have intermittent, watery diarrhea and others complain of alternating constipation and diarrhea. Stress may trigger nausea and abdominal distention and tenderness, but defecation usually relieves these signs and symptoms. Patients typically have an intense urge to defecate and feelings of incomplete evacuation. Typically, the stools are scybalous and contain visible mucus.

Mesenteric artery ischemia.

Mesenteric artery ischemia is a life-threatening disorder that produces sudden constipation with failure to expel stool or flatus. Initially, the abdomen is soft and nontender, but soon severe abdominal pain, tenderness, vomiting, and anorexia occur. Later, the patient may develop abdominal guarding, rigidity, and distention; tachycardia; syncope; tachypnea; a fever; and signs of shock, such as cool, clammy skin and hypotension. A bruit may be heard.

Spinal cord lesion.

Constipation may occur with a spinal cord lesion, in addition to urine retention, sexual dysfunction, pain and, possibly, motor weakness, paralysis, or sensory impairment below the level of the lesion.

Other causes

Diagnostic tests.

Constipation can result from the retention of barium given during certain GI studies.

Drugs.

Patients commonly experience constipation when taking an opioid analgesic or other drugs, including vinca alkaloids, calcium channel blockers, antacids containing aluminum or calcium, anticholinergics, and drugs with anticholinergic effects (such as tricyclic antidepressants). Patients may also experience constipation from excessive use of laxatives or enemas.

Surgery and radiation therapy.

Constipation can result from rectoanal surgery, which may traumatize nerves, and abdominal irradiation, which may cause intestinal stricture.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Signs & Symptoms (Third Edition), 2006

Constipation: Medical causes
(Professional Guide to Signs & Symptoms (Fifth Edition))

Anal fissure

A crack or laceration in the lining of the anal wall can cause acute constipation, usually due to the patient’s fear of the severe tearing or burning pain associated with bowel movements. He may notice a few drops of blood streaking toilet tissue or his underwear.

Anorectal abscess

In this disorder, constipation occurs together with severe, throbbing, localized pain and tenderness at the abscess site. The patient may also have localized inflammation, swelling, and purulent drainage and may complain of fever and malaise.

Cirrhosis

In the early stages of cirrhosis, the patient experiences constipation along with nausea and vomiting, and a dull pain in the right upper quadrant. Other early findings include indigestion, anorexia, fatigue, malaise, flatulence, hepatomegaly and, possibly, splenomegaly and diarrhea.

Diabetic neuropathy

This type of neuropathy produces episodic constipation or diarrhea. Other signs and symptoms include dysphagia, orthostatic hypotension, syncope, and painless bladder distention with overflow incontinence. A male patient may also experience impotence and retrograde ejaculation.

Diverticulitis

In this disorder, constipation or diarrhea occurs with left-lower-quadrant pain and tenderness and possibly a palpable, tender, firm, fixed abdominal mass. The patient may develop mild nausea, flatulence, or a low-grade fever.

Hemorrhoids

Thrombosed hemorrhoids cause constipation as the patient tries to avoid the severe pain of defecation. The hemorrhoids may bleed during defecation.

Hepatic porphyria

Abdominal pain, which may be severe, colicky, and localized or generalized, precedes constipation in hepatic porphyria. The patient may also have a fever, sinus tachycardia, labile hypertension, diaphoresis, severe vomiting, photophobia, urine retention, nervousness or restlessness, disorientation and, possibly, visual hallucinations. Deep tendon reflexes may be diminished or absent. Some patients have skin lesions causing itching, burning, erythema, altered pigmentation, and edema in areas exposed to light. Severe hepatic porphyria can produce delirium, coma, seizures, paraplegia, or complete flaccid quadriplegia.

Hypercalcemia

In hypercalcemia, constipation usually is accompanied by anorexia, nausea, vomiting, polyuria, and polydipsia. The patient may also display arrhythmias, bone pain, muscle weakness and atrophy, hypoactive deep tendon reflexes, and personality changes.

Hypothyroidism

Constipation occurs early and insidiously in patients with hypothyroidism; it may be accompanied by fatigue, sensitivity to cold, anorexia with weight gain, menorrhagia, decreased memory, hearing impairment, muscle cramps, and paresthesia.

Intestinal obstruction

Constipation associated with this disorder varies in severity and onset, depending on the location and extent of the obstruction. In a partial obstruction, constipation may alternate with leakage of liquid stools. In a complete obstruction, obstipation may occur. Constipation can be the earliest sign of partial colon obstruction, but it usually occurs later if the level of the obstruction is more proximal. Associated findings include episodes of colicky abdominal pain, abdominal distention, nausea, and vomiting. The patient may also develop hyperactive bowel sounds, visible peristaltic waves, a palpable abdominal mass, and abdominal tenderness.

Irritable bowel syndrome

This common syndrome usually produces chronic constipation, although some patients have intermittent watery diarrhea and others complain of alternating constipation and diarrhea. Stress may trigger nausea and abdominal distention and tenderness, but defecation usually relieves these signs and symptoms. Many patients have an intense urge to defecate and feelings of incomplete evacuation. Typically, the stools are scybalous and contain visible mucus.

Mesenteric artery ischemia

This life-threatening disorder produces sudden constipation with failure to expel stool or flatus. Initially, the abdomen is soft and nontender but soon severe abdominal pain, tenderness, vomiting, and anorexia occur. Later, the patient may develop abdominal guarding, rigidity, and distention; tachycardia; syncope; tachypnea; fever; and signs of shock, such as cool, clammy skin and hypotension. A bruit may be heard.

Multiple sclerosis (MS)

This disorder can produce constipation in addition to ocular disturbances, such as nystagmus, blurred vision, and diplopia; vertigo; and sensory disturbances. The patient may also have motor weakness, seizures, paralysis, muscle spasticity, gait ataxia, intention tremor, hyperreflexia, dysarthria, or dysphagia. MS can also produce urinary urgency, frequency, and incontinence as well as emotional instability. A male patient may experience impotence.

Spinal cord lesion

Constipation may occur in this disorder along with urine retention, sexual dysfunction, pain, and possibly motor weakness, paralysis, or sensory impairment below the level of the lesion.

Tabes dorsalis

In tabes dorsalis, constipation is accompanied by an ataxic gait; paresthesia; loss of sensation of body position, deep pain, and temperature; Charcot’s joints; Argyll Robertson pupils; diminished deep tendon reflexes; and possibly impotence.

Ulcerative colitis

Constipation may occur in patients with chronic ulcerative colitis, but bloody diarrhea with pus, mucus, or both is the hallmark of this disorder. Other signs and symptoms include cramping lower abdominal pain, tenesmus, anorexia, low-grade fever and, occasionally, nausea and vomiting. Bowel sounds may be hyperactive. Later, weight loss, weakness, and arthralgias occur.

Ulcerative proctitis

This disorder produces acute constipation with tenesmus. The patient feels an intense urge to defecate but is unable to do so. Instead, he may eliminate mucus, pus, or blood.

Other causes

Diagnostic tests

Constipation can result from the retention of barium given during certain GI studies.

Drugs

Many patients experience constipation when taking an opioid analgesic or other drugs, including vinca alkaloids, calcium channel blockers, antacids containing aluminum or calcium, anticholinergics, and drugs with anticholinergic effects (such as tricyclic antidepressants). Patients may also experience constipation from excessive use of laxatives or enemas.

Surgery and radiation therapy

Constipation can result from rectoanal surgery, which may traumatize nerves, and abdominal irradiation, which may cause intestinal stricture.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006

Constipation: Differential Overview
(Field Guide to Bedside Diagnosis)

❑ Lifestyle

❑ Drugs

❑ Depression

❑ Irritable bowel syndrome

❑ Pelvic floor dysfunction

❑ Hypothyroidism

❑ Hypokalemia

❑ Colon cancer

❑ Anorectal pathology

❑ Voluntary retention

❑ Megacolon

❑ Mechanical obstruction

❑ Spinal cord pathology

❑ Hypercalcemia

❑ Scleroderma

» READ BOOK EXCERPT ONLINE »

Source: Field Guide to Bedside Diagnosis, 2007

Intestinal obstruction: Causes
(Handbook of Diseases)

Adhesions and strangulated hernias usually cause small-bowel obstructions; carcinomas usually cause large-bowel obstructions. A mechanical intestinal obstruction results from a foreign body (fruit pits, gallstones, or worms) or compression of the bowel wall due to stenosis, intussusception, volvulus of the sigmoid or cecum, tumors, or atresia.

A nonmechanical obstruction results from a physiologic disturbance, such as paralytic ileus (see Paralytic ileus), electrolyte imbalance, toxicity (uremia or generalized infection), a neurogenic abnormality (spinal cord lesions), or thrombosis or embolism of mesenteric vessels.

The three forms of intestinal obstruction are:

simple — blockage prevents intestinal contents from passing with no other complications

strangulated — blood supply to part or all of the obstructed section is cut off in addition to blockage of the lumen

close looped — both ends of a bowel section are occluded, isolating it from the rest of the intestine.

In all three forms, the physiologic effects are similar. When intestinal obstruction occurs, fluid, air, and gas collect near the site. Peristalsis increases temporarily as the bowel tries to force its contents through the obstruction, injuring intestinal mucosa and causing distention at and above the site of the obstruction. This distention blocks the flow of venous blood and halts normal absorptive processes. As a result, the bowel begins to secrete water, sodium, and potassium into the fluid pooled in the lumen. This results in distention and enormous amounts of fluid in the gut.

An obstruction in the upper intestine results in metabolic alkalosis from dehydration and loss of gastric hydrochloric acid; a lower obstruction causes slower dehydration and loss of intestinal alkaline fluids, resulting in metabolic acidosis. Ultimately, an intestinal obstruction may lead to ischemia, necrosis, and death.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Chronic constipation: Causes
(Handbook of Diseases)

Chronic constipation usually results from some deficiency in the three elements necessary for normal bowel activity: dietary bulk, fluid intake, and exercise. Other possible causes can include habitual disregard of the impulse to defecate, emotional conflicts, overuse of laxatives, or prolonged dependence on enemas, which dull rectal sensitivity to the presence of stool. Certain medications (tranquilizers, anticholinergics, opioids, antacids) can cause it, and patients with certain disorders (Parkinson’s disease, multiple sclerosis, hypothyroidism, scleroderma, lupus erythematosus) are more prone to develop it.

Clinical tip  Anal fissure can also precipitate chronic constipation.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Constipation: Medical causes
(Signs & Symptoms: A 2-in-1 Reference for Nurses)

Anal fissure

An anal fissure, a crack or laceration in the lining of the anal wall, can cause acute constipation, usually due to the patient’s fear of the severe tearing or burning pain associated with bowel movements. He may notice a few drops of blood streaking toilet tissue or his underwear.

Anorectal abscess

With an anorectal abscess, constipation occurs with severe, throbbing, localized pain and tenderness at the abscess site. The patient may also have localized inflammation, swelling, and purulent drainage and may complain of fever and malaise.

Diverticulitis

With diverticulitis, constipation or diarrhea occurs with left-lower-quadrant pain and tenderness and possibly a palpable, tender, firm, fixed abdominal mass. The patient may develop mild nausea, flatulence, or a low-grade fever.

Hemorrhoids

Thrombosed hemorrhoids cause constipation as the patient tries to avoid the severe pain of defecation. The hemorrhoids may bleed during defecation. The patient may notice bright red blood on stools or toilet tissue.

Hepatic porphyria

Abdominal pain, which may be severe, colicky, localized, or generalized, precedes constipation in hepatic porphyria. The patient may also have fever, sinus tachycardia, labile hypertension, excessive diaphoresis, severe vomiting, photophobia, urine retention, nervousness or restlessness, disorientation and, possibly, visual hallucinations. Deep tendon reflexes may be diminished or absent. Some patients have skin lesions causing itching, burning, erythema, altered pigmentation, and edema in areas exposed to light. Severe hepatic porphyria can produce delirium, coma, seizures, paraplegia, or complete flaccid quadriplegia.

Hypercalcemia

With hypercalcemia, constipation usually occurs along with anorexia, nausea, vomiting, polyuria, and polydipsia. The patient may also display arrhythmias, bone pain, muscle weakness and atrophy, hypoactive deep tendon reflexes, and personality changes.

Hypothyroidism

Constipation occurs early and insidiously in patients with hypothyroidism, in addition to fatigue, sensitivity to cold, anorexia with weight gain, menorrhagia, decreased memory, hearing impairment, muscle cramps, and paresthesia.

Intestinal obstruction

Constipation associated with intestinal obstruction varies in severity and onset, depending on the location and extent of the obstruction. With partial obstruction, constipation may alternate with leakage of liquid stools. With complete obstruction, obstipation may occur. Constipation can be the earliest sign of partial colon obstruction, but it usually occurs later if the level of the obstruction is more proximal. Associated findings include episodes of colicky abdominal pain, abdominal distention, nausea, or vomiting. The patient may also develop hyperactive bowel sounds, visible peristaltic waves, a palpable abdominal mass, and abdominal tenderness.

Irritable bowel syndrome

Irritable bowel syndrome, a common disorder, usually produces chronic constipation, although some patients have intermittent, watery diarrhea and others complain of alternating constipation and diarrhea. Stress may trigger nausea and abdominal distention and tenderness, but defecation usually relieves these signs and symptoms. Patients with irritable bowel syndrome commonly have an intense urge to defecate and feelings of incomplete evacuation. Typically, the stools are scybalous and contain visible mucus.

Mesenteric artery ischemia

Mesenteric artery ischemia, a life-threatening disorder, produces sudden constipation with failure to expel stools or flatus. Initially, the abdomen is soft and nontender but soon severe abdominal pain, tenderness, vomiting, and anorexia occur. Later, the patient may develop abdominal guarding, rigidity, and distention; tachycardia; syncope; tachypnea; fever; and signs of shock, such as cool, clammy skin and hypotension. A bruit may be heard.

Multiple sclerosis

Multiple sclerosis (MS) can produce constipation in addition to ocular disturbances, such as nystagmus, blurred vision, and diplopia; vertigo; and sensory disturbances. The patient may also have motor weakness, seizures, paralysis, muscle spasticity, gait ataxia, intention tremor, hyperreflexia, dysarthria, or dysphagia. MS can also produce urinary urgency, frequency, and incontinence as well as emotional instability. A male patient may experience impotence.

Spinal cord lesion

Constipation may occur with a spinal cord lesion, in addition to urine retention, sexual dysfunction, pain and, possibly, motor weakness, paralysis, or sensory impairment below the level of the lesion.

Ulcerative colitis

Constipation may occur in patients with chronic ulcerative colitis, but bloody diarrhea with pus, mucus, or both is the hallmark of this disorder. Other signs and symptoms include cramping lower abdominal pain, tenesmus, anorexia, low-grade fever and, occasionally, nausea and vomiting. Bowel sounds may be hyperactive. Later, weight loss, weakness, and arthralgia occur.

Other causes

Diagnostic tests

Constipation can result from the retention of barium given during certain GI studies.

Drugs

Patients often experience constipation when taking an opioid analgesic or other drugs, including vinca alkaloids, calcium channel blockers, antacids containing aluminum or calcium, anticholinergics, and drugs with anticholinergic effects (such as tricyclic antidepressants). Patients may also experience constipation from excessive use of laxatives or enemas.

Surgery and radiation therapy

Constipation can result from rectoanal surgery, which may traumatize nerves, and abdominal irradiation, which may cause intestinal stricture.

» READ BOOK EXCERPT ONLINE »

Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007

Constipation: Principal Causes of Constipation
(The Diagnostic Approach to Symptoms and Signs in Pediatrics)

  1. Constitutional
    1. Geneticpredisposition
    2. Colonic inertia
  2. Dietary factors
  3. Developmental, situational, and psychologicdisturbances
  4. Gastrointestinal disorders
    1. Anal fissure
    2. Anal stenosis
    3. Anterior location of the anus
    4. Proctitis
    5. Congenital aganglionic megacolon
    6. Cystic fibrosis
    7. Celiac disease
    8. Chronic intestinal pseudoobstruction
  5. Abdominal, pelvic, and sacral masses
  6. Neurologic disorders
    1. Mentalretardation
    2. Spinal dysraphism
    3. Spinal cord injury
    4. Spinal tumor
    5. Neuromuscular disorders
  7. Metabolic disorders
  8. Drugs

» READ BOOK EXCERPT ONLINE »

Source: The Diagnostic Approach to Symptoms and Signs in Pediatrics, 2006

Constipation: Medical causes
(Nursing: Interpreting Signs and Symptoms)

Anal fissure.A crack or laceration in the lining of the anal wall can cause acute constipation, usually due to the patient's fear of the severe tearing or burning pain associated with bowel movements. He may notice a few drops of blood streaking toilet tissue or his underwear.

Anorectal abscess.In anorectal abscess, constipation occurs together with severe, throbbing, localized pain and tenderness at the abscess site. The patient may also have localized inflammation, swelling, and purulent drainage and may complain of fever and malaise.

Cirrhosis.In the early stages of cirrhosis, the patient experiences constipation along with nausea and vomiting and a dull pain in the right upper quadrant. Other early findings include indigestion, anorexia, fatigue, malaise, flatulence, hepatomegaly and, possibly, splenomegaly and diarrhea.

Diabetic neuropathy.Diabetic neuropathy produces episodic constipation or diarrhea. Other signs and symptoms include dysphagia, orthostatic hypotension, syncope, and painless bladder distention with overflow incontinence. A male patient may also experience impotence and retrograde ejaculation.

Diverticulitis.In diverticulitis, constipation or diarrhea occurs with left lower quadrant pain and tenderness and possibly a palpable, tender, firm, fixed abdominal mass. The patient may develop mild nausea, flatulence, or a low-grade fever.

Hemorrhoids.Thrombosed hemorrhoids cause constipation as the patient tries to avoid the severe pain of defecation. The hemorrhoids may bleed during defecation.

Hepatic porphyria.Abdominal pain, which may be severe, colicky, localized, or generalized, precedes constipation in hepatic porphyria. The patient may also have a fever, sinus tachycardia, labile hypertension, excessive diaphoresis, severe vomiting, photophobia, urine retention, nervousness or restlessness, disorientation and, possibly, visual hallucinations. Deep tendon reflexes may be diminished or absent. He may also have skin lesions causing itching, burning, erythema, altered pigmentation, and edema in areas exposed to light. Severe hepatic porphyria can produce delirium, coma, seizures, paraplegia, or complete flaccid quadriplegia.

Hypercalcemia.With hypercalcemia, constipation usually occurs along with anorexia, nausea, vomiting, polyuria, and polydipsia. The patient may also display arrhythmias, bone pain, muscle weakness and atrophy, hypoactive deep tendon reflexes, and personality changes.

Hypothyroidism.Constipation occurs early and insidiously in patients with hypothyroidism, in addition to fatigue, sensitivity to cold, anorexia with weight gain, menorrhagia in women, decreased memory, hearing impairment, muscle cramps, and paresthesia.

Intestinal obstruction.Constipation associated with an intestinal obstruction varies in severity and onset, depending on the location and extent of the obstruction. With partial obstruction, constipation may alternate with leakage of liquid stools. With complete obstruction, obstipation may occur. Constipation can be the earliest sign of partial colon obstruction, but it usually occurs later if the level of the obstruction is more proximal. Associated findings include episodes of colicky abdominal pain, abdominal distention, nausea, or vomiting. The patient may also develop hyperactive bowel sounds, visible peristaltic waves, a palpable abdominal mass, and abdominal tenderness.

Irritable bowel syndrome (IBS).IBS commonly produces chronic constipation, although some patients have intermittent, watery diarrhea and others complain of alternating constipation and diarrhea. Stress may trigger nausea and abdominal distention and tenderness, but defecation usually relieves these signs and symptoms. Patients typically have an intense urge to defecate and feelings of incomplete evacuation. Typically, the stools are scybalous and contain visible mucus.

Mesenteric artery ischemia.Mesenteric artery ischemia is a life-threatening disorder that produces sudden constipation with failure to expel stool or flatus. Initially, the abdomen is soft and nontender, but soon severe abdominal pain, tenderness, vomiting, and anorexia occur. Later, the patient may develop abdominal guarding, rigidity, and distention; tachycardia; syncope; tachypnea; a fever; and signs of shock, such as cool, clammy skin and hypotension. A bruit may be heard.

Spinal cord lesion.Constipation may occur with a spinal cord lesion, in addition to urine retention, sexual dysfunction, pain and, possibly, motor weakness, paralysis, or sensory impairment below the level of the lesion.

Other causes

Diagnostic tests.Constipation can result from the retention of barium given during certain GI studies.

Drugs.Patients commonly experience constipation when taking an opioid analgesic or other drugs, including vinca alkaloids, calcium channel blockers, antacids containing aluminum or calcium, anticholinergics, and drugs with anticholinergic effects (such as tricyclic antidepressants). Patients may also experience constipation from excessive use of laxatives or enemas.

Surgery and radiation therapy.Constipation can result from rectoanal surgery, which may traumatize nerves, and abdominal irradiation, which may cause intestinal stricture.

» READ BOOK EXCERPT ONLINE »

Source: Nursing: Interpreting Signs and Symptoms, 2007


 » Next page: Risk Factors for Intestinal Conditions

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