Iridocorneal Endothelial Syndrome

Introduction: Iridocorneal Endothelial Syndrome

Iridocorneal Endothelial Syndrome: ICE syndrome is actually a grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome; Chandler's ... more about Iridocorneal Endothelial Syndrome.

Iridocorneal Endothelial Syndrome: A condition which is characterized by glaucoma, iris atrophy, decreased endothelium, and iris nodules. More detailed information about the symptoms, causes, and treatments of Iridocorneal Endothelial Syndrome is available below.

Symptoms of Iridocorneal Endothelial Syndrome

• Iris distortion
• Pupil distortion
• Corneal swelling
• Glaucoma
• One-eye affected only

See full list of 8 symptoms of Iridocorneal Endothelial Syndrome

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Medical Textbooks Online about Iridocorneal Endothelial Syndrome

Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

Causes of Iridocorneal Endothelial Syndrome

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Article Excerpts about Iridocorneal Endothelial Syndrome

ICE syndrome is actually a grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome; Chandler's syndrome; and essential (progressive) iris atrophy (hence the acronym ICE). The most common feature of this group of diseases is the movement of endothelial cells off the cornea onto the iris. This loss of cells from the cornea often leads to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil, the adjustable opening at the center of the iris that allows varying amounts of light to enter the eye. This cell movement also plugs the fluid outflow channels of the eye, causing glaucoma. (Source: excerpt from Facts About the Cornea and Corneal Disease: NEI)

Definitions of Iridocorneal Endothelial Syndrome:

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Iridocorneal Endothelial Syndrome as a "rare disease".
Source - Orphanet