What is Jacobs syndrome?

What is Jacobs syndrome?

• Jacobs syndrome: A very rare syndrome characterized mainly by heart inflammation (pericardium), joint disease and permanent finger flexion. The number of joints affected is variable.

Jacobs syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Jacobs syndrome, or a subtype of Jacobs syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Jacobs syndrome as a "rare disease".
Source - Orphanet

Name and Aliases of Jacobs syndrome

Main name of condition: Jacobs syndrome

XYY syndrome, pericarditis [arthropathy - camptodactyly syndrome], arthropathy [camptodactyly syndrome], Arthropathy camptodactyly syndrome, Pericarditis arthropathy camptodactyly syndrome, PAC syndrome, Fibrosing serositis, familial, Camptodactyly arthropathy pericarditis syndrome, CAP Syndrome, Camptodactyly-arthropathy-coxa vara-pericarditis syndrome, Congenital familial hypertrophic synovitis

YY syndrome, 47 XYY syndrome, Double Y, XYY Karyotype, Arthropathy camptodactyly syndrome, CAP Syndrome, Camptodactyly arthropathy pericarditis syndrome, Camptodactyly-arthropathy-coxa vara-pericarditis syndrome, Congenital familial hypertrophic synovitis, Fibrosing serositis, familial, PAC syndrome, Pericarditis arthropathy camptodactyly syndrome
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)

Types of Jacobs syndrome:

Parent types of Jacobs syndrome: Sex chromosome conditions, Intersex conditions, Y Chromosome Disorders, X Chromosome Disorders

Organs Affected by Jacobs syndrome:

chromosome, x chromosome, y chromosome, sex chromosomes

How many people get Jacobs syndrome?

Prevalance of Jacobs syndrome: 1-in-2000 approximately.
Prevalance Rate of Jacobs syndrome: approx 1 in 2,000 or 0.05% or 136,000 people in USA [about data]

How serious is Jacobs syndrome?

Complications of Jacobs syndrome: see complications of Jacobs syndrome

What causes Jacobs syndrome?

Class of Condition for Jacobs syndrome: genetic sex chromosomal
Causes of Jacobs syndrome: see causes of Jacobs syndrome

Can anyone else get Jacobs syndrome?

Inheritance of genetic conditions: see details in inheritance of genetic diseases.

How is it treated?

Treatments for Jacobs syndrome: see treatments for Jacobs syndrome