The follow list shows some of the possible medical causes of Jacobs syndrome that are listed by the Diseases Database:
Other conditions that might have Jacobs syndrome as a complication may, potentially, be an underlying cause of Jacobs syndrome. Our database lists the following as having Jacobs syndrome as a complication of that condition:
Conditions listing Jacobs syndrome as a symptom may also be potential underlying causes of Jacobs syndrome. Our database lists the following as having Jacobs syndrome as a symptom of that condition:
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Jacobs syndrome may be found in:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Jacobs syndrome.
Neurogenic arthropathy is most common in men older than 40 years. In adults, the most common cause of neurogenic arthropathy is diabetes mellitus. Other causes include tabes dorsalis (especially among patients age 40 to 60), syringomyelia (progresses to neurogenic arthropathy in about 25% of patients),myelopathy of pernicious anemia, spinal cord trauma, paraplegia, hereditary sensory neuropathy, and Charcot-Marie-Tooth disease. Amyloidosis, peripheral nerve injury, myelomeningocele (in children), leprosy, and alcoholism may cause neurogenic arthropathy, but only in rare occurrences.
Frequent intra-articular injection of corticosteroids has also been linked to neurogenic arthropathy. The analgesic effect of the corticosteroids may mask symptoms and allow continuous stress to accelerate joint destruction.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Common causes of this disease include:
❑ bacterial, fungal, or viral infection (infectious pericarditis)
❑ neoplasms (primary or metastatic from lungs, breasts, or other organs)
❑ high-dose radiation to the chest
❑ uremia
❑ hypersensitivity or autoimmune disease, such as acute rheumatic fever (most common cause of pericarditis in children), systemic lupus erythematosus, and rheumatoid arthritis
❑ postcardiac injury such as myocardial infarction (MI), which later causes an autoimmune reaction (Dressler’s syndrome) in the pericardium; trauma; or surgery that leaves the pericardium intact but causes blood to leak into the pericardial cavity
❑ drugs, such as hydralazine or procainamide
❑ idiopathic factors (most common in acute pericarditis).
Less common causes include aortic aneurysm with pericardial leakage, and myxedema with cholesterol deposits in the pericardium.
Pericarditis most commonly affects men ages 20 to 50, but it can also occur in children following infection with an adenovirus or coxsackievirus.
Source: Professional Guide to Diseases (Eighth Edition), 2005
In adults, the most common cause of neurogenic arthropathy is diabetes mellitus. Other causes include tabes dorsalis (especially among patients ages 40 to 60), syringomyelia (which progresses to neurogenic arthropathy in about 25% of patients), myelopathy of pernicious anemia, spinal cord trauma, paraplegia, hereditary sensory neuropathy, and Charcot-Marie-Tooth disease. Rarely, amyloidosis, peripheral nerve injury, myelomeningocele (in children), leprosy, or alcoholism causes neurogenic arthropathy.
Frequent intra-articular injections of a corticosteroid have also been linked to neurogenic arthropathy. The analgesic effect of the corticosteroid may mask symptoms and allow continuous damaging stress to accelerate joint destruction.
Source: Handbook of Diseases, 2003
Common causes of this disease include:
❑ bacterial, fungal, or viral infection (infectious pericarditis)
❑ neoplasms (primary, or metastases from lungs, breasts, or other organs)
❑ high-dose radiation to the chest
❑ uremia
❑ hypersensitivity, systemic disease, or autoimmune disease, such as acute rheumatic fever (most common cause of pericarditis in children), systemic lupus erythematosus, acquired immuno-deficiency syndrome–related disorders, or rheumatoid arthritis
❑ postcardiac injury, such as myocardial infarction (MI), which later causes an autoimmune reaction (Dressler’s syndrome) in the pericardium; trauma or surgery that leaves the pericardium intact but causes blood to leak into the pericardial cavity
❑ drugs, such as hydralazine, nydrazid, phenytoin, and procainamide
❑ idiopathic factors (most common in acute pericarditis).
Less common causes include aortic aneurysm with pericardial leakage and myxedema with cholesterol deposits in the pericardium.
Source: Handbook of Diseases, 2003
Source: The 5-Minute Pediatric Consult, 2008
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