Jacobs syndrome

Introduction: Jacobs syndrome

A rare chromosomal genetic syndrome where the male person has an extra Y male chromosome, becoming XYY instead of normal XY (male) or XX (female). The person is male and may be mostly normal, or may suffer from minor features from excess male hormones, such as excess acne being very tall, and in some cases behavioral complaints such as aggression.

Symptoms of Jacobs syndrome

• Immaturity
• Learning difficulties
• Arthritis
• Camptodactyly
• Swollen joints

See full list of 9 symptoms of Jacobs syndrome

Medical Textbooks Online about Jacobs syndrome

Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

Less Common Symptoms of Jacobs syndrome

• Coxa vara
• Enlarged liver

Read more about symptoms of Jacobs syndrome

Wrongly Diagnosed with Jacobs syndrome?

• Underlying causes of Jacobs syndrome (possibly wrongly diagnosed)

Causes of Jacobs syndrome

• Serum sickness
• Sweet's disease
• Jacobs arthropathy-camptodactyly syndrome
• Hypertrophic pulmonary osteo-arthropathy
• Rhizomelic pseudopolyarthritis

See full list of 114 causes of Jacobs syndrome

Read more about causes of Jacobs syndrome.

More information about causes of Jacobs syndrome:

• Jacobs syndrome as a symptom

Videos for Jacobs syndrome

Patient Surveys for Jacobs syndrome

• Patient Profile Survey
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• Survey about the symptoms of your Jacobs syndrome
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Statistics for Jacobs syndrome

• Medical statistics for Jacobs syndrome
• Prevalence and incidence statistics for Jacobs syndrome
• Death and Mortality statistics for Jacobs syndrome
• Society statistics for Jacobs syndrome

Stories from Users Related to Jacobs syndrome

• Could I have fractured my knee cap?
• bursa has pushed knee cap over
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• Anyone ever heard of synovitis?
• knee cap
• Food under crown/cap
• TO: MBarry Re: What sort of tests did you have performed? For pericarditis.
• familial hypertrophic synovitis
• Jacobs Syndrome/ xyy Syndrome
• Cap-Tel Captioned Telephone
• Jacob Creutzfeld desease
• Pericarditis with no Cause
• Mrs Jacobs

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User Interactive Forums

Read about other experiences, ask a question about Jacobs syndrome, or answer someone else's question, on our message boards:

• I can not get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for this?
• See all the forums.

Definitions of Jacobs syndrome:

Jacobs syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Jacobs syndrome, or a subtype of Jacobs syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Jacobs syndrome as a "rare disease".
Source - Orphanet