1-in-2000 approximately. ... see also overview of Jacobs syndrome.
approx 1 in 2,000 or 0.05% or 136,000 people in USA [Source statistic for calcuation: "1-in-2000 approximately." -- see also general information about data sources]
Jacobs syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Jacobs syndrome, or a subtype of Jacobs syndrome, affects less than 200,000 people in the US population.
Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Jacobs syndrome as a "rare disease". More information about Jacobs syndrome is available from Orphanet
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Jacobs syndrome.
Common causes of this disease include:
❑ bacterial, fungal, or viral infection (infectious pericarditis)
❑ neoplasms (primary or metastatic from lungs, breasts, or other organs)
❑ high-dose radiation to the chest
❑ uremia
❑ hypersensitivity or autoimmune disease, such as acute rheumatic fever (most common cause of pericarditis in children), systemic lupus erythematosus, and rheumatoid arthritis
❑ postcardiac injury such as myocardial infarction (MI), which later causes an autoimmune reaction (Dressler’s syndrome) in the pericardium; trauma; or surgery that leaves the pericardium intact but causes blood to leak into the pericardial cavity
❑ drugs, such as hydralazine or procainamide
❑ idiopathic factors (most common in acute pericarditis).
Less common causes include aortic aneurysm with pericardial leakage, and myxedema with cholesterol deposits in the pericardium.
Pericarditis most commonly affects men ages 20 to 50, but it can also occur in children following infection with an adenovirus or coxsackievirus.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Source: The 5-Minute Pediatric Consult, 2008
The term 'prevalence' of Jacobs syndrome usually refers to the estimated population of people who are managing Jacobs syndrome at any given time. The term 'incidence' of Jacobs syndrome refers to the annual diagnosis rate, or the number of new cases of Jacobs syndrome diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.
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