The list of signs and symptoms mentioned in various sources for Jacobs syndrome includes the 9 symptoms listed below:
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Ocassionally other symptoms may also present themselves as symptoms of Jacobs syndrome. 2 of the more common ones are included in the list below:
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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.
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Neurogenic arthropathy begins insidiously with swelling, warmth, decreased mobility, and instability in a single joint or in many joints. It can progress to deformity. The first clue to vertebral neuroarthropathy, which progresses to gross spinal deformity, may be nothing more than a mild, persistent backache. Characteristically, pain is minimal despite obvious deformity.
The specific joint affected varies according to the underlying cause. Diabetes usually attacks the joints and bones of the feet; tabes dorsalis attacks the large weight-bearing joints, such as the knee, hip, ankle, or lumbar and dorsal vertebrae (Charcot spine); syringomyelia causes occurrence in the shoulder, elbow, or cervical intervertebral joint. Neurogenic arthropathy caused by intra-articular injection of corticosteroids usually develops in the hip or knee joint.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Acute pericarditis typically produces a sharp and often sudden pain that usually starts over the sternum and radiates to the neck, shoulders, back, and arms. However, unlike the pain of MI, pericardial pain is often pleuritic, increasing with deep inspiration and decreasing when the patient sits up and leans forward, pulling the heart away from the diaphragmatic pleurae of the lungs.
Pericardial effusion, the major complication of acute pericarditis, may produce effects of heart failure (such as dyspnea, orthopnea, and tachycardia), ill-defined substernal chest pain, and a feeling of fullness in the chest. (See Patterns of cardiac pain.)
Chronic constrictive pericarditis causes a gradual increase in systemic venous pressure and produces symptoms similar to those of chronic right-sided heart failure (fluid retention, ascites, and hepatomegaly).
Source: Professional Guide to Diseases (Eighth Edition), 2005
Neurogenic arthropathy begins insidiously with swelling, warmth, increased mobility, and instability in a single joint or in many joints. It can progress to deformity. The first clue to vertebral neuroarthropathy, which progresses to gross spinal deformity, may be nothing more than a mild, persistent backache. Characteristically, pain is minimal despite obvious deformity.
The specific joint that’s affected varies. Diabetes usually attacks the joints and bones of the feet; tabes dorsalis attacks the large weight-bearing joints, such as the knee, hip, ankle, or lumbar and dorsal vertebrae (Charcot spine); syringomyelia, the shoulder, elbow, or cervical intervertebral joint. Neurogenic arthropathy related to intra-articular injection of a corticosteroid usually develops in the hip or knee joint.
Source: Handbook of Diseases, 2003
Clinical features vary in the acute and chronic forms.
In acute pericarditis, a sharp and commonly sudden pain usually starts over the sternum and radiates to the neck, shoulders, back, and arms. However, unlike the pain of an MI, pericardial pain is often pleuritic, increasing with deep inspiration and decreasing when the patient sits up and leans forward, pulling the heart away from the diaphragmatic pleurae of the lungs.
Pericardial effusion, the major complication of acute pericarditis, may produce the effects of heart failure — such as dyspnea, orthopnea, and tachycardia — as well as ill-defined substernal chest pain and a feeling of fullness in the chest.
If the fluid accumulates rapidly, cardiac tamponade may occur, resulting in pallor, clammy skin, hypotension, paradoxical pulse (a decrease in systolic blood pressure equal to or greater than 10 mm Hg during slow inspiration), jugular vein distention and, eventually, cardiovascular collapse and death.
Chronic constrictive pericarditis causes a gradual increase in systemic venous pressure and produces symptoms similar to those of chronic right-sided heart failure (fluid retention, ascites, hepatomegaly).
Source: Handbook of Diseases, 2003
Source: The 5-Minute Pediatric Consult, 2008
These general reference articles may be of interest
in relation to medical signs and symptoms of disease in general:
Full list of premium articles on symptoms and diagnosis
The symptom information on this page
attempts to provide a list of some possible signs and symptoms of Jacobs syndrome.
This signs and symptoms information for Jacobs syndrome has been gathered from various sources,
may not be fully accurate,
and may not be the full list of Jacobs syndrome signs or Jacobs syndrome symptoms.
Furthermore, signs and symptoms of Jacobs syndrome may vary on an individual basis for each patient.
Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they
are indeed Jacobs syndrome symptoms.
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Medical Articles:
Neurogenic arthropathy:
Signs and symptoms
(Handbook of Diseases)
Pericarditis:
Signs and symptoms
(Handbook of Diseases)
Acute pericarditis
Chronic pericarditis
Pericarditis:
Pericarditis - signs & symptoms
(The 5-Minute Pediatric Consult)
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