Kernicterus: A rare condition involving high blood levels of bilirubin which can also accumulate in the brain and lead to neurological problems. More detailed information about the symptoms, causes, and treatments of Kernicterus is available below.
See full list of 19 symptoms of Kernicterus
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A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613) - (Source - Diseases Database)
An abnormal accumulation of bile pigment in the brain and other nerve tissue; causes yellow staining and tissue damage - (Source - WordNet 2.1)
Kernicterus is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Kernicterus, or a subtype of Kernicterus,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
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