The list of signs and symptoms mentioned in various sources for Klinefelter syndrome includes the 30 symptoms listed below:
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The list of other diseases or medical conditions that may be on the differential diagnosis list of alternative diagnoses for Klinefelter syndrome includes:
See the full list of 3 alternative diagnoses for Klinefelter syndrome
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Medical Books Excerpts Excerpts of published medical book chapters related to Klinefelter syndrome are available from published medical books for more detailed information about Klinefelter syndrome.
Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.
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Klinefelter's syndrome may not be apparent until puberty or later in mild cases. Because many of these patients aren't mentally retarded, behavioral problems in adolescence or infertility may be the only presenting features initially.
The syndrome's characteristic features include a small penis and prostate gland, small testicles, sparse facial and abdominal hair, feminine distribution of pubic hair (triangular shape), sexual dysfunction (impotence, lack of libido) and, in fewer than 50% of patients, gynecomastia. Aspermatogenesis and infertility result from progressive sclerosis and hyalinization of the seminiferous tubules in the testicles and from testicular fibrosis during and after puberty. In the mosaic form of Klinefelter's syndrome, such pathologic changes and resulting infertility may be delayed.
Klinefelter's syndrome may also be associated with osteoporosis, abnormal body build (long legs with short, obese trunk), tall stature, learning disabilities characterized by poor verbal skills and, in some individuals, behavioral problems beginning in adolescence. It's also associated with an increased incidence of pulmonary disease and varicose veins and a significantly increased rate of breast cancer because of the extra X chromosome.
Source: Professional Guide to Diseases (Eighth Edition), 2005
When considering symptoms of Klinefelter syndrome, it is also important to consider Klinefelter syndrome as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that Klinefelter syndrome may cause:
These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:
Full list of premium articles on symptoms and diagnosis
The symptom information on this page attempts to provide a list of some possible signs and symptoms of Klinefelter syndrome. This signs and symptoms information for Klinefelter syndrome has been gathered from various sources, may not be fully accurate, and may not be the full list of Klinefelter syndrome signs or Klinefelter syndrome symptoms. Furthermore, signs and symptoms of Klinefelter syndrome may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Klinefelter syndrome symptoms.
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