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Lactic Acidosis

Lactic Acidosis: Excerpt from A Pocket Manual of Differential Diagnosis

Associated with Impaired Tissue Oxygenation


Shock (e.g., hypovolemic, cardiogenic, septic)
Hypoxemia, respiratory failure
Anemia, severe

Occurring in Absence of Apparent Hypoxemia or Circulatory Insufficiency


Diabetes, uncontrolled
Hepatic failure
Renal failure
Malignancy, especially leukemia or lymphoma
Drugs, toxins
   Cyanide
   Carbon monoxide
   Methanol
   Salicylates
   Iron
   Strychnine
   Ethanol
Seizures
Excessive muscular activity (e.g., excessive exercise)
Alkalosis, respiratory or metabolic
d-Lactic acidosis (secondary to intestinal bacterial overgrowth)
Congenital enzyme deficiency (e.g., glycogen storage
disease)

References

1. Shapiro JI, Kaehny WD: Pathogenesis and Management of Metabolic Acidosis and Alkalosis, p. 130. See Bibliography, 4.
2. Rose, p. 554. See Bibliography, 3.
3. Kreisberg RA: Lactate Homeostasis and Lactic Acidosis. Ann Intern Med   92:227, 1980.

Book Source Details

  • Book Title: A Pocket Manual of Differential Diagnosis
  • Author(s): Stephen N. Adler, Dianne B. Gasbarra
  • Year of Publication: 1999
  • Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 1999 Lippincott Williams & Wilkins.

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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.




More About This Book:
Title: A Pocket Manual of Differential Diagnosis
Authors: Stephen N. Adler, Dianne B. Gasbarra
Publisher: Lippincott Williams & Wilkins
Copyright: 1999
ISBN: 0-78171-943-7

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