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A swab from the site of infection (urethra, cervix, or rectum) establishes a diagnosis of urethritis, cervicitis, salpingitis, endometritis, or proctitis. A culture of aspirated material establishes a diagnosis of epididymitis.
Antigen detection methods, including the enzyme-linked immunosorbent assay and the direct fluorescent antibody test, have long been used for identifying chlamydial infection. Tissue cell cultures, however, are more sensitive and specific. Newer nucleic acid probes using polymerase chain reactions are also commercially available and have become the diagnostic tests of choice.
Source: Professional Guide to Diseases (Eighth Edition), 2005
The following laboratory test results provide a definitive diagnosis of chlamydial infection:
❑ A swab from the site of infection (urethra, cervix, or rectum) establishes a diagnosis of urethritis, cervicitis, salpingitis, endometritis, or proctitis.
❑ A culture of aspirated material establishes a diagnosis of epididymitis.
❑ Antigen detection methods, including the enzyme-linked immunosorbent assay and the direct fluorescent antibody test, are the diagnostic tests of choice for identifying chlamydial infection, although tissue cell cultures are more sensitive and specific.
❑ Newer nucleic acid probes using polymerase chain reactions are also commercially available.
Source: Handbook of Diseases, 2003
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