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Causes of Lysinuric protein intolerance

Lysinuric protein intolerance Causes: Book Excerpts

Related information on causes of Lysinuric protein intolerance:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Lysinuric protein intolerance may be found in:

Causes of Lysinuric protein intolerance: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Lysinuric protein intolerance.

Milk Protein Intolerance: Milk Protein Intolerance - pathophysiology
(The 5-Minute Pediatric Consult)

  • Unprocessed cow’s milk protein is 80% casein and 20% whey. The whey fraction contains >20 types of antigenic proteins, including β-lactoglobulin (the most allergenic of all), α-lactalbumin, bovine serum albumin, βExclusively breastfed infants may also develop milk protein intolerance through exposure to allergens that appear in breast milk.
  • Although β-lactoglobulin is suspected to be an antigen, no single protein fraction has been proven. Most children appear to be allergic to multiple cow’s milk proteins; rarely are patients allergic to only one fraction.
  • There is 25–30% cross-reactivity between milk proteins and soy proteins.

Milk Protein Intolerance - etiology

Predisposing factors include:

  • Age (diagnosis usually <2 years)
  • Immune deficiency (immaturity of the mucosal immune system, immaturity or damage of mucosal barrier function, low IgA)
  • History or presence of atopy
  • Early milk protein–based formula feeding
  • Allergenic formula
  • GI infection
>

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008


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