Causes of Lysinuric protein intolerance
Lysinuric protein intolerance Causes: Book Excerpts
Related information on causes of Lysinuric protein intolerance:
As with all medical conditions,
there may be many causal factors.
Further relevant information on causes of Lysinuric protein intolerance may be found in:
Causes of Lysinuric protein intolerance: Online Medical Books
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Milk Protein Intolerance:
Milk Protein Intolerance - pathophysiology
(The 5-Minute Pediatric Consult)
- Unprocessed cow’s milk protein is 80% casein and 20% whey. The whey fraction contains >20 types of antigenic proteins, including β-lactoglobulin (the most allergenic of all), α-lactalbumin, bovine serum albumin, βExclusively breastfed infants may also develop milk protein intolerance through exposure to allergens that appear in breast milk.
- Although β-lactoglobulin is suspected to be an antigen, no single protein fraction has been proven. Most children appear to be allergic to multiple cow’s milk proteins; rarely are patients allergic to only one fraction.
- There is 25–30% cross-reactivity between milk proteins and soy proteins.
Milk Protein Intolerance - etiology
Predisposing factors include:
- Age (diagnosis usually <2 years)
- Immune deficiency (immaturity of the mucosal immune system, immaturity or damage of mucosal barrier function, low IgA)
- History or presence of atopy
- Early milk protein–based formula feeding
- Allergenic formula
- GI infection
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Source: The 5-Minute Pediatric Consult, 2008
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Symptoms of Lysinuric protein intolerance
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