Symptoms of Marburg virus

Symptoms of Marburg virus

The list of signs and symptoms mentioned in various sources for Marburg virus includes the 42 symptoms listed below:

• Phase 1:
  • Sudden onset
  • Fever
  • Chills
  • Headache
  • Myalgia
• Phase 2:
  • Maculopapular rash
  • Trunk rash
  • Nausea
  • Vomiting
  • Chest pain
  • A sore throat
  • Abdominal pain
  • Diarrhea
  • Jaundice
  • Pancreas inflammation
  • Severe weight loss
  • Delirium
  • Shock
  • Liver failure
  • Massive hemorrhaging
  • Multi-organ dysfunction
• Fever
• Nausea
• Vomiting
• Chest pain
• Sore throat
• Abdominal pain
• Diarrhea
• Headache
• Muscle pain
• Rash
• Jaundice
• Pancreatitis
• Weight loss
• Delirium
• Neuropsychotic symptoms
• Hemorrhage
• Hypovolemic shock
• Multi-organ dysfunction
• Liver failure
• more information...»

Research symptoms & diagnosis of Marburg virus:

• Overview -- Marburg virus
• Diagnostic Tests for Marburg virus
• Home Diagnostic Testing
• Complications -- Marburg virus
• Misdiagnosis and Alternative Diagnoses
• Hidden Causes of Marburg virus
• Other Causes -- causes of these or similar symptoms

Marburg virus: Complications

Review medical complications possibly associated with Marburg virus:

• Multi-organ dysfunction
• Liver failure
• Pancreas inflammation (see Pancreas symptoms)
• Orchititis (see Testicle pain)
• Hepatitis
• Recurrent hepatitis (see Liver symptoms)
• Transverse myelitis
• more complications...»

Research More About Marburg virus

Do I have Marburg virus?

• Marburg virus: Introduction
• Marburg virus: Diagnostic Testing to confirm diagnosis
• Home Diagnostic Testing
• Alternative diagnoses and misdiagnosis for Marburg virus
• How serious is it?
• Treatments for Marburg virus
• More about Marburg virus

Home Diagnostic Testing

Home medical tests related to Marburg virus:

• Cold & Flu: Home Testing:
  • Home Fever Tests
  • Home Ear Infection Test Kits
  • Home Flu Tests
  • Home Strep A Tests
• more home tests...»

Wrongly Diagnosed with Marburg virus?

The list of other diseases or medical conditions that may be on the differential diagnosis list of alternative diagnoses for Marburg virus includes:

• Malaria
• Typhoid fever
• more diagnoses...»

See the full list of 2 alternative diagnoses for Marburg virus

More about symptoms of Marburg virus:

More information about symptoms of Marburg virus and related conditions:

• Other diseases with similar symptoms and common misdiagnoses
• Tests to determine if these are the symptoms of Marburg virus
• Symptoms that may be caused by complications of Marburg virus
• Associated conditions for Marburg virus
• Risk factors for Marburg virus

Other Possible Causes of these Symptoms

Click on any of the symptoms below to see a full list of other causes including diseases, medical conditions, toxins, drug interactions, or drug side effect causes of that symptom.

• A sore throat - see all causes of Sore throat
• Abdominal pain - see all causes of Abdominal pain
• Abdominal pain - see all causes of Abdominal pain
• Chest pain - see all causes of Chest pain
• Chest pain - see all causes of Chest pain
• Chills - see all causes of Chills
• Delirium - see all causes of Delirium
• Delirium - see all causes of Delirium
• Diarrhea - see all causes of Diarrhea
• Diarrhea - see all causes of Diarrhea
• Fever - see all causes of Fever
• Fever - see all causes of Fever
• Headache - see all causes of Headache
• Headache - see all causes of Headache
• Hemorrhage - see all causes of Bleeding symptoms
• Jaundice - see all causes of Jaundice
• Jaundice - see all causes of Jaundice
• Liver failure - see all causes of Liver failure
• Liver failure - see all causes of Liver failure
• Maculopapular rash - see all causes of Maculopapular rash
• Massive hemorrhaging - see all causes of Bleeding symptoms
• Muscle pain - see all causes of Muscle pain
• Myalgia - see all causes of Myalgia
• Nausea - see all causes of Nausea
• Nausea - see all causes of Nausea
• Pancreas inflammation - see all causes of Pancreas symptoms
• Pancreatitis - see all causes of Pancreatitis
• Rash - see all causes of Rash
• Severe weight loss - see all causes of Weight loss
• Shock - see all causes of Shock
• Sore throat - see all causes of Sore throat
• Sudden onset
• Trunk rash - see all causes of Rash
• Vomiting - see all causes of Vomiting
• Vomiting - see all causes of Vomiting
• Weight loss - see all causes of Weight loss

Medical Books Online about Marburg virus

Medical Books Excerpts Excerpts of published medical book chapters related to Marburg virus are available from published medical books for more detailed information about Marburg virus.

Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

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Symptoms of Marburg virus: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the symptoms of Marburg virus.

Allergic purpuras: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

Characteristic skin lesions of allergic purpura are purple, macular, ecchymotic, and of varying size. They’re caused by vascular leakage into the skin and mucous membranes. (See Purpuric lesions.) The lesions usually appear in symmetric patterns on the arms, legs, and buttocks and are accompanied by pruritus, paresthesia and, occasionally, angioneurotic edema. In children, skin lesions are generally urticarial and expand and become hemorrhagic. Scattered petechiae may appear on the legs, buttocks, and perineum.

Henoch-Schönlein syndrome commonly produces transient or severe colic, tenesmus (spasmodic contraction of the anal sphincter) and constipation, vomiting, and edema or hemorrhage of the mucous membranes of the bowel, resulting in GI bleeding, occult blood in the stool and, possibly, intussusception. Such GI abnormalities may precede overt, cutaneous signs of purpura. Musculoskeletal symptoms, such as rheumatoid pains and periarticular effusions, mostly affect the legs and feet.

In 25% to 50% of patients, allergic purpura is associated with GU signs and symptoms: nephritis; renal hemorrhages that may cause microscopic hematuria and disturb renal function; bleeding from the mucosal surfaces of the ureters, bladder, or urethra; and, occasionally, glomerulonephritis. Also possible are moderate and irregular fever, headache, anorexia, and localized edema of the hands, feet, or scalp.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Colorado tick fever: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

After a 3- to 6-day incubation period, Colorado tick fever begins abruptly with chills; temperature of 104° F (40° C); severe aching of back, arms, and legs; lethargy; and headache with eye movement such as extraocular movement. Photophobia, abdominal pain, nausea, and vomiting may occur. Rare effects include petechial or maculopapular rashes and central nervous system involvement. Symptoms subside after several days but return within 2 to 3 days and continue for 3 more days before slowly disappearing. Complete recovery usually follows.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Idiopathic thrombocytopenic purpura: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

Clinical features of ITP common to all forms of thrombocytopenia include petechiae, ecchymoses, and mucosal bleeding from the mouth, nose, or GI tract. Generally, hemorrhage is a rare physical finding. Purpuric lesions may occur in vital organs, such as the lungs, kidneys, or brain, and may prove fatal. In acute ITP, which commonly occurs in children, onset is usually sudden, causing easy bruising, epistaxis, and bleeding gums. Onset of chronic ITP is insidious.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Lassa fever: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

After a 7- to 18-day incubation period, this disease produces a fever that persists for 2 to 3 weeks, exudative pharyngitis, oral ulcers, lymphadenopathy with swelling of the face and neck, purpura, conjunctivitis, and bradycardia. Severe infection may also cause hepatitis, myocarditis, pleural infection, encephalitis, and permanent unilateral or bilateral deafness.

Virus multiplication in reticuloendothelial cells causes capillary lesions that lead to erythrocyte and platelet loss; mild to moderate thrombocytopenia (with a tendency toward bleeding); and secondary bacterial infection. These capillary lesions may also cause focal hemorrhage in the stomach, small intestine, kidneys, lungs, and brain and, possibly, hemorrhagic shock and peripheral vascular collapse.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Relapsing fever: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

The incubation period for relapsing fever is 5 to 15 days (the average is 7 days). Clinically, tick- and louse-borne diseases are similar. Both begin suddenly, with a temperature approaching 105° F (40.6° C), prostration, headache, severe myalgia, arthralgia, diarrhea, vomiting, coughing, and eye or chest pains. Splenomegaly is common; hepatomegaly and lymphade-nopathy may occur. During febrile periods, the victim's pulse and respiratory rates rise, and a transient macular rash may develop over his torso.

The first attack usually lasts from 3 to 6 days; then the patient's temperature drops quickly and is accompanied by profuse sweating. A skin rash on the trunk lasting 1 to 2 days is common after the primary febrile episode. The rash may be petechiae, macular, or papular. About 5 to 10 days later, a second febrile, symptomatic period begins. In louse-borne infection, additional relapses are unusual; but, in tick-borne cases, a second or third relapse is common. As the afebrile intervals become longer, relapses become shorter and milder because of antibody accumulation. Relapses are possibly due to antigenic changes in the Borrelia organism.

Complications from relapsing fever include nephritis, bronchitis, pneumonia, endocarditis, seizures, cranial nerve lesions, paralysis, and coma. Death may occur from hyperpyrexia, massive bleeding, circulatory failure, splenic rupture, or a secondary infection.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Rheumatic fever and rheumatic heart disease: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

In 95% of patients, rheumatic fever characteristically follows a streptococcal infection that appeared a few days to 6 weeks earlier. A temperature of at least 100.4° F (38° C) occurs, and most patients complain of migratory joint pain or polyarthritis. Swelling, redness, and signs of effusion usually accompany such pain, which most commonly affects the knees, ankles, elbows, or hips. In 5% of patients (generally those with carditis), rheumatic fever causes skin lesions such as erythema marginatum, a nonpruritic, macular, transient rash that gives rise to red lesions with blanched centers. Rheumatic fever may also produce firm, movable, nontender, subcutaneous nodules about 3 mm to 2 cm in diameter, usually near tendons or bony prominences of joints (especially the elbows, knuckles, wrists, and knees) and less often on the scalp and backs of the hands. These nodules persist for a few days to several weeks and, like erythema marginatum, often accompany carditis.

Later, rheumatic fever may cause transient chorea, which develops up to 6 months after the original streptococcal infection. Mild chorea may produce hyperirritability, a deterioration in handwriting, or an inability to concentrate. Severe chorea (Sydenham’s chorea) causes purposeless, nonrepetitive, involuntary muscle spasms; poor muscle coordination; and weakness. Chorea always resolves without residual neurologic damage.

The most destructive effect of rheumatic fever is carditis, which develops in up to 50% of patients and may affect the endocardium, myocardium, pericardium, or the heart valves. Pericarditis causes a pericardial friction rub and, occasionally, pain and effusion. Myocarditis produces characteristic lesions called Aschoff bodies (in the acute stages) and cellular swelling and fragmentation of interstitial collagen, leading to formation of a progressively fibrotic nodule and interstitial scars. Endocarditis causes valve leaflet swelling, erosion along the lines of leaflet closure, and blood, platelet, and fibrin deposits, which form beadlike vegetations. Endocarditis affects the mitral valve most often in females; the aortic, most often in males. In both females and males, endocarditis affects the tricuspid valves occasionally and the pulmonic only rarely.

Severe rheumatic carditis may cause heart failure with dyspnea; right upper quadrant pain; tachycardia; tachypnea; a hacking, nonproductive cough; edema; and significant mitral and aortic murmurs. The most common of such murmurs include:

❑ a systolic murmur of mitral insufficiency (high-pitched, blowing, holosystolic, loudest at apex, possibly radiating to the anterior axillary line)

❑ a midsystolic murmur due to stiffening and swelling of the mitral leaflet

❑ occasionally, a diastolic murmur of aortic insufficiency (low-pitched, rumbling, almost inaudible). Valvular disease may eventually result in chronic valvular stenosis and insufficiency, including mitral stenosis and insufficiency, and aortic insufficiency. In children, mitral insufficiency remains the major sequela of rheumatic heart disease.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Rocky Mountain spotted fever: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

The incubation period is usually about 7 days, but it can range from 2 to 14 days. Generally, the shorter the incubation time, the more severe the infection. Signs and symptoms, which usually begin abruptly, include a persistent temperature of 102° to 104° F (38.9° to 40° C); a generalized, excruciating headache; nausea and vomiting; and aching in the bones, muscles, joints, and back. In addition, the tongue is covered with a thick white coating that gradually turns brown as the fever persists and rises.

Initially, the skin may simply appear flushed. Between days 2 and 5, eruptions begin around the wrists, ankles, or forehead; within 2 days, they cover the entire body, including the scalp, palms, and soles. The rash consists of erythematous macules 1 to 5 mm in diameter that blanch on pressure; if untreated, the rash may become petechial and maculopapular. By the third week, the skin peels off and may become gangrenous over the elbows, fingers, and toes.

The pulse is strong initially, but it gradually becomes rapid (possibly reaching 150 beats/minute) and thready.

Alert A rapid pulse rate and hypotension (systolic pressure less than 90 mm Hg) herald imminent death from complete vascular collapse.

Other signs and symptoms include a bronchial cough, a rapid respiratory rate (as high as 60 breaths/minute), anorexia, constipation, abdominal pain, hepatomegaly, splenomegaly, insomnia, restlessness and, in extreme cases, delirium. Urine output falls to half of the normal level or less, is dark in color, and contains albumin. Complications, although uncommon, include lobar pneumonia, otitis media, pa-rotitis, disseminated intravascular coagulation (DIC) and, possibly, renal failure. In rare cases, RMSF leads to death.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Allergic purpura: Signs and symptoms
(Handbook of Diseases)

Allergic purpura is characterized by purple skin lesions that are macular, ecchymotic, and varying in size, usually appearing in symmetrical patterns on the arms and legs. The lesions are caused by vascular leakage into the skin and mucous membranes and are accompanied by pruritus, paresthesia and, occasionally, angioneurotic edema. In children, the lesions are generally urticarial, and they usually expand and become hemorrhagic. Scattered petechiae may appear on the legs, buttocks, and perineum.

Henoch-Schönlein syndrome commonly produces transient or severe colic, tenesmus (spasmodic contraction of the anal sphincter) and constipation, vomiting, and edema or hemorrhage of the mucous membranes of the bowel, resulting in GI bleeding, occult blood in the stool and, possibly, intussusception. Such GI abnormalities may precede overt, cutaneous signs of purpura. Musculoskeletal symptoms, such as rheumatoid pain and periarticular effusion, mostly affect the legs and feet.

In 25% to 50% of patients, allergic purpura is associated with GU signs and symptoms: nephritis; renal hemorrhages that may cause microscopic hematuria and disturb renal function; bleeding from the mucosal surfaces of the ureters, bladder, or urethra; and, occasionally, glomerulonephritis.

Other signs and symptoms include moderate and irregular fever, headache, anorexia, and localized edema of the hands, feet, or scalp.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Idiopathic thrombocytopenic purpura: Signs and symptoms
(Handbook of Diseases)

Signs and symptoms of ITP common to all forms of thrombocytopenia include petechiae, ecchymoses, and mucosal bleeding from the mouth, nose, and GI tract. Generally, hemorrhage is a rare physical finding. Purpuric lesions may occur in vital organs, such as the lungs, kidneys, or brain, and may prove fatal.

With acute ITP, which is common in children, onset is usually sudden and without warning, causing easy bruising, epistaxis, and bleeding gums. Onset of chronic ITP is insidious.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Rheumatic fever and rheumatic heart disease: Signs and symptoms
(Handbook of Diseases)

In 95% of patients, rheumatic fever characteristically follows a streptococcal infection that appeared a few days to 6 weeks earlier. A temperature of at least 100.4° F (38° C) occurs.

Joint pain

Most patients complain of migratory joint pain or polyarthritis. Swelling, redness, and signs of effusion usually accompany such pain, which most commonly affects the knees, ankles, elbows, or hips.

Skin lesions and nodules

In 5% of patients (generally those with carditis), rheumatic fever causes skin lesions, such as erythema marginatum. This nonpruritic, macular, transient rash gives rise to red lesions with blanched centers.

Rheumatic fever may also produce firm, movable, nontender, subcutaneous nodules ⅛" to ¾" (0.5 to 2 cm) in diameter, usually near tendons or bony prominences of joints (especially the elbows, knuckles, wrists, and knees) and less commonly on the scalp and backs of the hands. These nodules persist for a few days to several weeks and, like erythema marginatum, often accompany carditis.

Chorea

Later, rheumatic fever may cause transient chorea, which develops up to 6 months after the original streptococcal infection.

Mild chorea may produce hyperirritability, a deterioration in handwriting, or an inability to concentrate. Severe chorea causes purposeless, nonrepetitive, involuntary muscle spasms; poor muscle coordination; and weakness. Chorea always resolves without residual neurologic damage.

Carditis

The most destructive effect of rheumatic fever is carditis, which develops in up to 50% of patients. It may affect the endocardium, myocardium, pericardium, or the heart valves.

Pericarditis causes a pericardial friction rub and, occasionally, pain and effusion. Myocarditis produces characteristic lesions called Aschoff bodies (in the acute stages) and cellular swelling and fragmentation of interstitial collagen, leading to formation of a progressively fibrotic nodule and interstitial scars.

Endocarditis causes valve leaflet swelling, erosion along the lines of leaflet closure, and blood, platelet, and fibrin deposits, which form beadlike vegetations. Endocarditis usually affects the mitral valve in females and the aortic valve in males. In both sexes, endocarditis affects the tricuspid valves occasionally and the pulmonic valve only rarely.

Severe rheumatic carditis may cause heart failure with dyspnea, right-upper-quadrant pain, tachycardia, tachypnea, significant mitral and aortic murmurs, and a hacking, nonproductive cough.

The most common murmurs include:

❑ a systolic murmur of mitral insufficiency (high-pitched, blowing, holo-systolic, loudest at apex, possibly radiating to the anterior axillary line)

❑ a midsystolic murmur caused by stiffening and swelling of the mitral leaflet

❑ occasionally, a diastolic murmur of aortic insufficiency. Valvular disease may eventually result in chronic valvular stenosis and insufficiency, including mitral stenosis and insufficiency and aortic insufficiency. In children, mitral insufficiency remains the major after-effect of rheumatic heart disease.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Article Excerpts About Symptoms of Marburg virus:

After an incubation period of 5-10 days, the onset of the disease is sudden and is marked by fever, chills, headache, and myalgia. Around the fifth day after the onset of symptoms, a maculopapular rash, most prominent on the trunk (chest, back, stomach), may occur. Nausea, vomiting, chest pain, a sore throat, abdominal pain, and diarrhea then may appear.   Symptoms become increasingly severe and may include jaundice, inflammation of the pancreas, severe weight loss, delirium, shock, liver failure, massive hemorrhaging, and multi-organ dysfunction. (Source: excerpt from Marburg Hemorrhagic Fever: DVRD)

Marburg virus as a Cause of Symptoms or Medical Conditions

When considering symptoms of Marburg virus, it is also important to consider Marburg virus as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that Marburg virus may cause:

• Viral haemorrhagic fever

Marburg virus: Onset and Incubation

Incubation period for Marburg virus: 5-10 days

Medical articles and books on symptoms:

These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:

• Diagnostic Testing for a Diagnosis of Marburg virus
• Research Alternative Diagnoses for Marburg virus
• How serious is Marburg virus?
• More about Marburg virus
• Online Diagnosis
• Self Diagnosis Pitfalls
• Pitfalls of Online Diagnosis
• Symptoms of the Silent Killer Diseases
• Lesser known silent killer diseases
• Books on signs and symptoms

Full list of premium articles on symptoms and diagnosis

About signs and symptoms of Marburg virus:

The symptom information on this page attempts to provide a list of some possible signs and symptoms of Marburg virus. This signs and symptoms information for Marburg virus has been gathered from various sources, may not be fully accurate, and may not be the full list of Marburg virus signs or Marburg virus symptoms. Furthermore, signs and symptoms of Marburg virus may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Marburg virus symptoms.