Prevalence and Incidence of Marfan syndrome
Prevalance of Marfan syndrome:
1 per 5,000 people are affected by Marfan syndrome worldwide, Genetics Home Reference website ... see also overview of Marfan syndrome.
Prevalance Rate:
approx 1 in 5,000 or 0.02% or 54,400 people in USA [Source statistic for calcuation: "1 per 5,000 people are affected by Marfan syndrome worldwide, Genetics Home Reference website" -- see also general information about data sources]
Marfan syndrome: Rare Disease
Marfan syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Marfan syndrome, or a subtype of Marfan syndrome,
affects less than 200,000 people in the US population.
Ophanet, who are a consortium of European partners,
currently defines a condition rare when if affects 1 person per 2,000.
They list Marfan syndrome as a "rare disease".
More information about Marfan syndrome is available from Orphanet
Marfan syndrome Prevalence: Book Excerpts
Prevalance of Marfan syndrome:
It is
estimated that at least 1 in 5,000 people in the United States have the
disorder.
(Source: excerpt from Questions and Answers about Marfan Syndrome: NIAMS)
Prevelance statistics for Marfan syndrome:
The following statistics relate to the prevalence of Marfan syndrome:
- More than 200,000 people are affected by Marfan syndrome and related conditions in the US (American Journal of Cardiology, 1995, National Marfan Foundation)
- more statistics...»
More Statistics about Marfan syndrome:
Survival rate statistics
All statistics for Marfan syndrome
Prevalence/Incidence of Marfan syndrome: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the prevalence and/or incidence of Marfan syndrome.
Scoliosis:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
Scoliosis may be functional, structural, or idiopathic. Functional (postural) scoliosis usually results from a discrepancy in leg lengths rather than from a fixed deformity of the spinal column; it corrects when the patient bends toward the convex side. Structural scoliosis results from a deformity of the vertebral bodies, and it doesn’t correct when the patient bends to the side. Structural scoliosis may be:
❑ congenital: usually related to a congenital defect, such as wedge vertebrae, fused ribs or vertebrae, or hemivertebrae; may result from trauma to zygote or embryo
❑ paralytic or musculoskeletal: develops several months after asymmetrical paralysis of the trunk muscles due to polio, cerebral palsy, or muscular dystrophy
❑ idiopathic (the most common form): may be transmitted as an autosomal dominant or multifactorial trait. This form appears in a previously straight spine during the growing years. Brain stem dysfunction, possibly due to a lesion of the posterior columns or the inner ear, may be the cause.
Idiopathic scoliosis can be classified as infantile, which affects mostly male infants between birth and age 3 and causes left thoracic and right lumbar curves; juvenile, which affects both sexes between ages 4 and 10 and causes varying types of curvature; or adolescent, which generally affects girls between age 10 and achievement of skeletal maturity and causes varying types of curvature.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
About prevalence and incidence statistics:
The term 'prevalence' of Marfan syndrome usually refers to the estimated population
of people who are managing Marfan syndrome at any given time.
The term 'incidence' of Marfan syndrome refers to the annual diagnosis rate,
or the number of new cases of Marfan syndrome diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
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