Treatments for Mastocytosis
Treatments for Mastocytosis
The list of treatments mentioned in various sources
for Mastocytosis
includes the following list.
Always seek professional medical advice about any treatment
or change in treatment plans.
- Usually no treatment is required and the skin bumps disappear with age. Problematic causes may require theuse of antihistamine medication to manage the itching and other cases may require the bumps to be surgically removed
Drugs and Medications used to treat Mastocytosis:
Note:You must always seek professional medical advice about any prescription drug, OTC drug, medication, treatment
or change in treatment plans.
Some of the different medications used in the treatment of Mastocytosis include:
Discussion of treatments for Mastocytosis:
Several medicines help treat
the symptoms of mastocytosis.
- Antihistamines to work against mast cell chemicals
- Medicines to relieve cramping in the intestines
Medicines help treat other signs and symptoms of
mastocytosis, including
- Itching and other skin reactions
- Ulcer-like symptoms
- Low blood pressure
- Inability to take up nutrients from food
In rare cases
in which mastocytosis is cancerous or associated with a blood
disorder, the patient may have to use steroids and/or chemotherapy.
(Source: excerpt from
Mastocytosis, NIAID Fact Sheet: NIAID)
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Urticaria:
Treatment
(In a Page: Signs and Symptoms)
-
Identify and avoid physical or drug triggers
-
Systemic antihistamines (e.g., hydroxyzine, doxepin, cimetidine) are helpful and may be used alone or in combination with each other or with nonsedating antihistamines (e.g., loratidine, cetirizine, fexofenadine)
-
Severe attacks with associated angioedema may require administration of prednisone and epinephrine (consider pen-type epinephrine injector such as Epi-PenR)
-
Danazol is used to treat only the rare, hereditary subset of angioedema (without urticaria); it stimulates hepatic production of the dysfunctional or absent C1 esterase inhibitor, thereby normalizing the complement cascade
-
Treat yeast, tinea, or bacterial infections of the skin, mucosa, sinuses, or other locations with appropriate antifungal or antibacterial preparations
-
Treat thyroid disease if found
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» READ BOOK EXCERPT ONLINE »
Source: In a Page: Signs and Symptoms, 2004
Urticaria:
Treatment
(In A Page: Pediatric Signs and Symptoms)
- Urticaria: Antihistamine; if nonresponsive to antihistamine or chronic uritcaria, then use corticosteroids
- Severe angioedema/anaphylaxis: ABCs of resuscitation
–Epinephrine: 1:1,000, 0.01 mg/kg SC (1:10,000 IV/IO if in shock), every 15 minutes up to three doses, maximum cumulative dose: 0.3 mg (child), 0.5 mg (adult)
–IV fluids if hypotension
–Nebulized Albuterol; antihistamine; corticosteroid (for
late phase)
–Observation: Mild, 2–4 hrs; severe, 12–24 hours
–Consult pediatric allergist
–Give patient EpiPen for self-administration
-
Hereditary angioedema
–C1 esterase inhibitor concentrate; adults, danazol
-
Avoid exposure to causative agents
-
Desensitization to insect venoms
-
Treat underlying disorders
» READ BOOK EXCERPT ONLINE »
Source: In A Page: Pediatric Signs and Symptoms, 2007
Urticaria [Hives]:
Emergency interventions
(Handbook of Signs & Symptoms (Third Edition))
In an acute case of urticaria, quickly evaluate respiratory status, and take vital signs. Ensure patent I.V. access if you note any respiratory difficulty or signs of impending anaphylactic shock. Also, as appropriate, give local epinephrine or apply ice to the affected site to decrease absorption through vasoconstriction. Clear and maintain the airway, give oxygen as needed, and institute cardiac monitoring. Have resuscitation equipment at hand, and be prepared to begin cardiopulmonary resuscitation. Intubation or a tracheostomy may be required.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Signs & Symptoms (Third Edition), 2006
Cutaneous larva migrans:
Treatment
(Professional Guide to Diseases (Eighth Edition))
Topical application of thiabendazole, ivermectin, or albendazole is effective. The suspension is applied to lesions and the immediate surrounding areas four times daily for 1 week. Oral thiabendazole given in two divided doses for 3 to 5 days is effective. Oral ivermectin and albendazole are equally effective. Tell the patient that adverse effects of systemic thiabendazole include nausea, vomiting, abdominal pain, and dizziness.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Urticaria and angioedema:
Treatment
(Professional Guide to Diseases (Eighth Edition))
Treatment aims to prevent or limit contact with triggering factors or, if this is impossible, to desensitize the patient to them and to relieve symptoms. During desensitization, progressively larger doses of specific antigens (determined by skin testing) are injected intradermally. After the triggering stimulus has been removed, urticaria usually subsides in a few days — except for drug reactions, which may persist as long as the drug is in the bloodstream.
Diphenhydramine, hydroxyzine, or another antihistamine can ease itching and swelling in every kind of urticaria. Corticosteroid therapy may be necessary for some patients.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Urticaria [Hives]:
Emergency Interventions
(Professional Guide to Signs & Symptoms (Fifth Edition))
In a patient with acute urticaria, quickly evaluate his respiratory status and take his vital signs. Ensure patent I.V. access if you note respiratory difficulty or signs of impending anaphylactic shock. Also, as appropriate, give local epinephrine or apply ice to the affected site to decrease absorption of the irritating agent through vasoconstriction. Clear and maintain the airway, give oxygen as needed, and institute cardiac monitoring. Have resuscitation equipment at hand, and be prepared to begin cardiopulmonary resuscitation. Intubation or a tracheostomy may be required.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006
Urticaria and angioedema:
Treatment
(Handbook of Diseases)
Treatment aims to prevent or limit contact with triggering factors or, if this is impossible, to desensitize the patient to them and relieve symptoms. Once the triggering stimulus has been removed, urticaria usually subsides in a few days. (Drug reactions may persist until the drug is no longer in the bloodstream.)
During desensitization, progressively larger doses of specific antigens (determined by skin testing) are injected intradermally. Antihistamines such as hydroxyzine can ease itching and swelling in every kind of urticaria, although they may induce drowsiness.
Corticosteroid therapy may be necessary for some patients.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Urticaria:
Nursing considerations
(Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series)
To help relieve the patient’s discomfort, apply a bland skin emollient or one containing menthol and phenol. Expect to give an antihistamine, a systemic corticosteroid or, if stress is a suspected contributing factor, a tranquilizer. Tepid baths and cool compresses may also enhance vasoconstriction and decrease pruritus.
Patient teaching
Teach the patient to avoid the causative stimulus, if appropriate. Emphasize the importance of wearing a medical alert bracelet that identifies his allergies. Explain the risks of delayed symptoms and which signs and symptoms to report. Discuss methods and techniques to prevent anaphylaxis. Instruct the patient on the proper use of an anaphylaxis kit and epinephrine administration.
» READ BOOK EXCERPT ONLINE »
Source: Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series, 2007
Urticaria:
Emergency Actions
(Signs & Symptoms: A 2-in-1 Reference for Nurses)
In an acute case of urticaria, quickly evaluate respiratory status and take vital signs. Ensure patent I.V. access if you note any respiratory difficulty or signs of impending anaphylactic shock. Also, as appropriate, give local epinephrine or apply ice to the affected site to decrease absorption through vasoconstriction. Maintain a patent airway, give oxygen as needed, and institute cardiac monitoring. Have resuscitation equipment at hand, and be prepared to begin cardiopulmonary resuscitation. Intubation or a tracheostomy may be required.
» READ BOOK EXCERPT ONLINE »
Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007
Urticaria [Hives]:
Nursing considerations
(Nursing: Interpreting Signs and Symptoms)
▪ Apply a bland skin emollient or one containing menthol and phenol to the patient's skin.
▪ Administer an antihistamine, a systemic corticosteroid or, if stress is a suspected contributing factor, a tranquilizer, as ordered.
▪ Provide tepid baths and cool compresses to enhance vasoconstriction and decrease pruritus.
▪ Administer oxygen and monitor respiratory status.
Patient teaching
▪ Explain the underlying disorder and treatment plan.
▪ Teach the patient to avoid the causative stimulus, if identified.
▪ Emphasize the importance of wearing medical identification for allergies.
▪ Explain signs and symptoms that require prompt medical attention.
▪ Stress ways to avoid anaphylaxis.
▪ Teach the patient and his family how to use an anaphylaxis kit.
» READ BOOK EXCERPT ONLINE »
Source: Nursing: Interpreting Signs and Symptoms, 2007
Urticaria:
Urticaria - TREATMENT
(The 5-Minute Pediatric Consult)
Emergent Treatment
If any difficulty breathing, stridor or wheezing, or other signs of anaphylaxis, give epinephrine 0.01 mL/kg of the 1:1,000 solution SC/IM
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
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