The list of treatments mentioned in various sources for Melioidosis includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.
The first step in getting correct treatment is to get a correct diagnosis. Differential diagnosis list for Melioidosis may include:
The following are some of the latest treatments for Melioidosis:
These medical statistics relate to hospitals, hospitalization and Melioidosis:
ost cases of melioidosis can be treated with appropriate antibiotics. Burkholderia psuedomallei, the organism that causes melioidosis, is usually sensitive to imipenem, penicillin, doxycycline, amoxycillin-clavulanic acid, azlocillin, ceftazidime, ticarcillin-vulanic acid, ceftriaxone, and aztreonam. Treatment should be initiated early in the course of the disease. Although bloodstream infection with melioidosis can be fatal, the other types of the disease are nonfatal. The type of infection and the course of treatment can predict any long-term sequelae. (Source: excerpt from Melioidosis: DBMD)
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In the debilitated or otherwise vulnerable patient with clinical evidence of Pseudo-monas infection, treatment should begin immediately, without waiting for results of laboratory tests. Antibiotic treatment includes aminoglycosides, such as gentamicin or tobramycin, combined with an antipseudomonal penicillin, such as ticarcillin or piperacillin. An alternative combination is amikacin and a similar penicillin or imipenem and cilastatin. Such combination therapy is necessary because Pseudomonas quickly becomes resistant to ticarcillin alone.
Local Pseudomonas infections or septicemia secondary to wound infection requires 1% acetic acid irrigations; topical applications of colistimethate, polymyxin B, and silver sulfadiazine cream; and debridement or drainage of the infected wound.
Source: Professional Guide to Diseases (Eighth Edition), 2005
In the debilitated or otherwise vulnerable patient with clinical evidence of Pseudomonas infection, treatment should begin immediately, even before the results of laboratory tests are received.
Antibiotic treatment includes aminoglycosides, such as gentamicin or tobramycin, combined with a Pseudo-monas-sensitive penicillin, such as carbenicillin disodium or ticarcillin. An alternative combination is amikacin and a similar penicillin. Such combination therapy is necessary because Pseu-domonas quickly becomes resistant to carbenicillin alone.
CLINICAL TIP: In bacteremia, an aminoglycoside and beta-lactam antibiotic with anti-Pseudo-monals activity increases survival rates.
In urinary tract infections, carbenicillin indanyl sodium can be used alone if the organism is susceptible and the infection doesn’t have systemic effects; it’s excreted in the urine and builds up high urine levels that prevent resistance.
Local Pseudomonas infections or septicemia secondary to wound infection require 1% acetic acid irrigations, topical application of colistimethate sodium and polymyxin B, and debridement or drainage of the infected wound.
Source: Handbook of Diseases, 2003
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