Clinical Trials for Mental retardation
Clinical trials are research studies conducted in an effort to improve overall patient health and care.
Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition.
Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks.
A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.
A brief description of each phase:
- Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
- Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
- Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
- Phase IV: These studies monitor long-term side effects after the treatment has been marketed.
Clinical Trials data for Mental retardation is grouped into the following categories:-
The format for each of the following is:
- The name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
- followed by a list of drug/s, if any, used in the trial
ClinicalTrials.gov has listed the following trials for Mental retardation:
- Study of Proteus Syndrome and Related Congenital Disorders - This study is currently recruiting patients (Current: 23 Nov 2006)
- Genetic Aspects of Neurologic and Psychiatric Disorders - This study has been completed (Current: 23 Nov 2006)
- Evaluation of Patients With Unresolved Chromosome Abnormalities - This study has been completed (Current: 23 Nov 2006)
- Phase II Study of Stereotypes and Mental Retardation: Neurobiological Basis - This study has been suspended (Current: 23 Nov 2006) - bromocriptine,sertraline hydrochloride
- Use of Sustained Release Antiepileptic Medication (Depakote ER) for Pediatric Epilepsy in a Mental Retardation/Developmental Disorder Population - This study is currently recruiting patients (Current: 23 Nov 2006)
- Prevalence of Spasticity in Adults With Mental Retardation Living in the Community - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
- Open Label Study of Zonisamide in the Treatment of Epilepsy in Patients With Mental Retardation - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Protein Synthesis in the Brain of Patients With Fragile X Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
- Study of Smith-Lemli-Opitz Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Cholesterol Suspension
- Atypical Neuroleptic Drugs in People With Mental Retardation/Developmental Delay - This study has been completed (Current: 23 Nov 2006) - risperidone,clozapine,olanzapine
- Self-Injury: Diagnosis and Treatment - This study is no longer recruiting patients (Current: 23 Nov 2006) - Naltrexone hydrochloride
- MR Scanning of Very Young Children With Severe Developmental Disorders - This study has been completed (Current: 23 Nov 2006)
- Copper Histidine Therapy for Menkes Diseases - This study is currently recruiting patients (Current: 23 Nov 2006) - Copper Histidine
- Phase II Pilot Study of Aminoimidazole Carboxamide Riboside (AICAR), a Precursor of Purine Synthesis, for Lesch-Nyhan Disease - This study has been completed (Current: 23 Nov 2006) - aminomidazole carboxamide riboside
- Study of Glyceryl Trierucate and Glyceryl Trioleate (Lorenzo's Oil) Therapy in Male Children With Adrenoleukodystrophy - This study is currently recruiting patients (Current: 23 Nov 2006) - glyceryl trierucate,glyceryl trioleate
- Study of Bile Acids in Patients With Peroxisomal Disorders - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - chenodeoxycholic acid,cholic acid,ursodiol
- Randomized Study of Beta Interferon and Thalidomide in Patients With Adrenoleukodystrophy - This study has been completed (Current: 23 Nov 2006) - glyceryl trierucate,glyceryl trioleate,interferon beta,thalidomide
- Phase I/II Study of Retroviral-Mediated Transfer of Iduronate-2-Sulfatase Gene Into Lymphocytes of Patients With Mucopolysaccharidosis II (Mild Hunter Syndrome) - This study has been completed (Current: 23 Nov 2006)
- Nutritional Aspects of Rett Syndrome - This study has been completed (Current: 23 Nov 2006)
- Study of Cardiac and Paroxysmal Abnormalities in Rett Syndrome - This study has been completed (Current: 23 Nov 2006)
- Study of the Pathogenesis of Rett Syndrome - This study has been completed (Current: 23 Nov 2006) - dextromethorphan,topiramate,Donepezil
- Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Study of Oral Cholic Acid in Patients With Inborn Errors of Bile Acid Synthesis - This study has been completed (Current: 23 Nov 2006)
- Effects of CX516 on Functioning in Fragile X Syndrome and Autism - This study has been completed (Current: 23 Nov 2006) - CX516 (Ampalex®)
- Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - dextromethorphan,donepezil hydrochloride
- Iduronate-2-Sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Iduronate-2-sulfatase enzyme replacement therapy
- Stem Cell Transplant for Inborn Errors of Metabolism - This study is currently recruiting patients (Current: 23 Nov 2006) - Busulfan,Cyclophosphamide,ATG
- An Open-Label Trial of Donepezil in Fragile X Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Donepezil
- A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Children With Autistic Disorder and Other Pervasive Developmental Disorders (PDD) - This study is no longer recruiting patients (Current: 23 Nov 2006) - risperidone
- Clinical Study and Gene Mutation Analysis of Adrenoleukodystrophy in Taiwanese Children - This study is currently recruiting patients (Current: 23 Nov 2006)
- Genetic and Physical Characteristics of Rett Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
- HSCT for High Risk Inherited Inborn Errors - This study is currently recruiting patients (Current: 23 Nov 2006) - Campath,Clofarabine
- Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian Disorders - This study is currently recruiting patients (Current: 23 Nov 2006) - 18 FDG
- Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion Syndromes - This study has been completed (Current: 23 Nov 2006)
- Reproduction and Survival After Cardiac Defect Repair - This study has been completed (Current: 23 Nov 2006)
- Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Vitamin D Metabolism and the Williams Syndrome - This study has been completed (Current: 23 Nov 2006) - Vitamin D
- Vitamin E in Aging Persons With Down Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Vitamin E,multivitamin
- Treatment of Self-Injurious Behavior in Individuals With Prader-Willi Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Topiramate
- Memantine and Down's Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Memantine Hydrochloride
- Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency - This study is currently recruiting patients (Current: 23 Nov 2006)
- Efficacy Study of Folinic Acid to Improve Mental Development of Children With Down Syndrome - This study has been completed (Current: 23 Nov 2006) - folinic acid
- Nordic Study on the Effects of Growth Hormone (Norditropin SimpleXx) Treatment in Adults With Prader-Willi Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Norditropin SimpleXx
- Characteristics of Prader-Willi Syndrome and Early-Onset Morbid Obesity - This study is currently recruiting patients (Current: 23 Nov 2006)
- Down Syndrome and Continuous Positive Pressure Therapy - This study is currently recruiting patients (Current: 23 Nov 2006)
- Investigation of the Developmental, Nutritional and Hormonal Regulation of Ghrelin in Children With Prader-Willi Syndrome - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Octreotide
- Molecular Analysis of Microphthalmia/Anophthalmia - This study is currently recruiting patients (Current: 23 Nov 2006)
- Simvastatin Therapy in Smith-Lemli-Opitz Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Simvastatin Susp.,OraPlus
- Effects of Enzyme Replacement in Gaucher's Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Macrophage-targeted glucocerebrosidase
- Cause and Pathogenesis of Neurometabolic Disorders - This study is currently recruiting patients (Current: 23 Nov 2006)
- Study of Inborn Errors of Cholesterol Synthesis and Related Disorders - This study is currently recruiting patients (Current: 23 Nov 2006)
- Akathisia (Restless Legs Syndrome) in People With Schizophrenia and Mental Retardation - This study has been completed (Current: 23 Nov 2006)
- Magnesium Sulfate to Prevent Brain Injury in Premature Infants - This study is no longer recruiting patients (Current: 23 Nov 2006) - magnesium sulfate
- Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - crystalline cholesterol oil-based suspension
- Agenesis of the Corpus Callosum & Aicardi Syndrome Research Project - This study is currently recruiting patients (Current: 23 Nov 2006)
- Dietary Supplements for the Treatment of Angelman Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Betaine,Creatine,Metafolin,Vitamin B12
The format for each of the following is:
- The drug,
- followed by the name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
ClinicalTrials.gov has listed the following drugs in trials for Mental retardation:
The trial data on this page has been sourced from
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