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Metabolic Alkalosis

Metabolic Alkalosis: Excerpt from A Pocket Manual of Differential Diagnosis

Chloride-Responsive (Urine Cl <10 mEq/L)


Vomiting, nasogastric suction
Gastric drainage or fistula
Diuretics
Posthypercapnic state
Villous adenoma of colon
Congenital chloride diarrhea
Cystic fibrosis

Chloride-Resistant (Urine Cl    >20 mEq/L)


Primary aldosteronism
Secondary aldosteronism
   Congestive heart failure
   Cirrhosis and ascites
   Malignant hypertension
   Adrenocorticotropic hormone (ACTH) or glucocorticoid excess (Cushing's disease, Cushing's syndrome, ectopic ACTH production)
   Bartter's syndrome
   Gitelman's syndrome
   Renin-secreting tumor (e.g., hemangiopericytoma)
Licorice ingestion
Excessive use of chewing tobacco
Severe potassium depletion
Congenital adrenal hyperplasia
Liddle's syndrome

Miscellaneous


Administration of alkali or alkalinizing agents, especially in the presence of renal insufficiency:
   Alkalinizing agents (e.g., citrate, lactate)
   Antacids (milk-alkali syndrome)
   Massive transfusion of blood or plasma substitute
Nonparathyroid hypercalcemia (e.g., bone metastases, multiple myeloma)
Nonreabsorbable anionic antibiotics, large doses (e.g., penicillin, carbenicillin)
Glucose ingestion after starvation

References

1. Shapiro JI, Kaehny WD: Pathogenesis and Management of Metabolic Acidosis and Alkalosis, p. 130. See Bibliography, 4.
2. Rose, p. 515. See Bibliography, 3.
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Book Source Details

  • Book Title: A Pocket Manual of Differential Diagnosis
  • Author(s): Stephen N. Adler, Dianne B. Gasbarra
  • Year of Publication: 1999
  • Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 1999 Lippincott Williams & Wilkins.

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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.




More About This Book:
Title: A Pocket Manual of Differential Diagnosis
Authors: Stephen N. Adler, Dianne B. Gasbarra
Publisher: Lippincott Williams & Wilkins
Copyright: 1999
ISBN: 0-78171-943-7

 » Next page: Introduction: Metabolism (Professional Guide to Diseases (Eighth Edition))

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