Causes: Multiple endocrine neoplasia:
Endocrine glands are different from other organs in the body because they release hormones into the bloodstream. Hormones are powerful chemicals that travel through the blood, controlling and instructing the functions of various organs. Normally, the hormones released by endocrine glands are carefully balanced to met the body's needs. When a person has MEN, specific endocrine glands, such as the parathyroid glands, the pancreas gland, and the pituitary gland, tend to become overactive. When these glands go into overdrive, the result can be: excessive calcium in the bloodstream (resulting in kidney stones or kidney damage); fatigue; weakness; muscle or bone pain; constipation; indigestion; and thinning of bones.
(Source: Genes and Disease by the National Center for Biotechnology)
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Multiple endocrine neoplasia may be found in:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Multiple endocrine neoplasia.
MEN usually results from autosomal dominant inheritance. It affects males twice as often as females and may occur at any time from adolescence to old age, but is rare in children.There’s no racial predilection.
Source: Professional Guide to Diseases (Eighth Edition), 2005
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