What is Multiple endocrine neoplasia type 1?
What is Multiple endocrine neoplasia type 1?
- Multiple endocrine neoplasia type 1: Rare inherited disease causing tumors in multiple glands.
- Multiple endocrine neoplasia type 1: The MEN1 gene is a cloned tumor suppressor gene for Multiple Endocrine Neoplasia, a predisposition for endocrine tumors and carcinoid tumors. The gene encodes the tumor suppressor protein MEN1, which regulates transcription through direct interaction with, and inhibition of, transcription factor JunD. Menin also interacts with SMAD3 and appears to be required for SMAD3/4-DNA binding at transcriptional regulatory sites. The human gene is located at 11q13.
Source - Diseases Database
Multiple endocrine neoplasia type 1 is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Multiple endocrine neoplasia type 1, or a subtype of Multiple endocrine neoplasia type 1,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Multiple endocrine neoplasia type 1 as a "rare disease".
Source - Orphanet
Multiple endocrine neoplasia type 1: Introduction
Types of Multiple endocrine neoplasia type 1:
Broader types of Multiple endocrine neoplasia type 1:
How many people get Multiple endocrine neoplasia type 1?
Prevalance of Multiple endocrine neoplasia type 1: 3 per 100,000 up to 20 per 100,000 (NIDDK)
Prevalance Rate of Multiple endocrine neoplasia type 1: approx 1 in 33,333 or 0.00% or 8,160 people in USA [about data]
Prevalance of Multiple endocrine neoplasia type 1:
MEN1 is quite rare, occurring in about
3 to 20 persons out of 100,000.
(Source: excerpt from Multiple Endocrine Neoplasia Type 1: NIDDK)
Who gets Multiple endocrine neoplasia type 1?
Profile for Multiple endocrine neoplasia type 1:
It affects both sexes equally and shows no
geographical, racial, or ethnic preferences.
(Source: excerpt from Multiple Endocrine Neoplasia Type 1: NIDDK)
How serious is Multiple endocrine neoplasia type 1?
Complications of Multiple endocrine neoplasia type 1:
see complications of Multiple endocrine neoplasia type 1
Prognosis of Multiple endocrine neoplasia type 1:
Most people with MEN1 will have long and
productive lives.
(Source: excerpt from Multiple Endocrine Neoplasia Type 1: NIDDK)
What causes Multiple endocrine neoplasia type 1?
Causes of Multiple endocrine neoplasia type 1: see causes of Multiple endocrine neoplasia type 1
What are the symptoms of Multiple endocrine neoplasia type 1?
Symptoms of Multiple endocrine neoplasia type 1:
see symptoms of Multiple endocrine neoplasia type 1
Complications of Multiple endocrine neoplasia type 1:
see complications of Multiple endocrine neoplasia type 1
Onset of Multiple endocrine neoplasia type 1: any age after 1st decade
Can anyone else get Multiple endocrine neoplasia type 1?
Contagion of genetic conditions:
generally not; see details in contagion of genetic diseases.
More information:
see contagiousness of Multiple endocrine neoplasia type 1
Inheritance of genetic conditions: see details in inheritance of genetic diseases.
Multiple endocrine neoplasia type 1: Testing
Diagnostic testing: see tests for Multiple endocrine neoplasia type 1.
Misdiagnosis: see misdiagnosis and Multiple endocrine neoplasia type 1.
How is it treated?
Treatments for Multiple endocrine neoplasia type 1:
see treatments for Multiple endocrine neoplasia type 1
Research for Multiple endocrine neoplasia type 1:
see research for Multiple endocrine neoplasia type 1
Organs Affected by Multiple endocrine neoplasia type 1:
Organs and body systems related to Multiple endocrine neoplasia type 1 include:
Name and Aliases of Multiple endocrine neoplasia type 1
Main name of condition: Multiple endocrine neoplasia type 1
Class of Condition for Multiple endocrine neoplasia type 1: genetic
Other names or spellings for Multiple endocrine neoplasia type 1:
MEN1, MEN I, Wermer's syndrome, Familial endocrine neoplasia type I, Endocrine adenoma-peptic ulcer complex, MEA, multiple endocrine adenomatosis I, multiple endocrine neoplasia I, pluriglandular adenomatosis I
MEN type 1, Wermer's syndrome
Source - Diseases Database
Multiple endocrine adenomatosis, Multiple endocrine neoplasia, Wermer syndrome, Zollinger-Ellison syndrome, Zollinger-Ellison syndrome, MEN 1, Multiple endocrine adenomatosis, Multiple endocrine neoplasia
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)
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