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AMN

More information on medical condition: Adrenoleukodystrophy:

Disease: AMN (Adrenoleukodystrophy)

AMN: Another name for Adrenoleukodystrophy.

AMN (condition): A rare disorder which has characteristic symptoms of Addison disease (adrenocortical insufficiency) and Schilder disease (cerebral sclerosis). Bronze skin, brain sclerosis and demyelination are the main symptoms.

Article Excerpts Related to Disease AMN (Adrenoleukodystrophy)

AMN: Adrenoleukodystrophy (ALD) is a rare, inherited metabolic disorder that afflicts the young boy Lorenzo Odone, whose story is told in the 1993 film "Lorenzo's oil." In this disease, the fatty covering (myelin sheath) on nerve fibers in the brain is lost, and the adrenal gland degenerates, leading to progressive neurological disability and death. (Source: Genes and Disease by the National Center for Biotechnology)

Adrenoleukodystrophy (ALD) is a rare, genetic disorder characterized by the breakdown or loss of the myelin sheath surrounding nerve cells in the brain and progressive dysfunction of the adrenal gland. ALD is one of a group of genetic disorders called the leukodystrophies that cause damage to the myelin sheath, the fatty covering — which acts as an insulator — on nerve fibers in the brain. (Source: excerpt from NINDS Adrenoleukodystrophy Information Page: NINDS)

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