Acetazolamide

Introduction: Acetazolamide

Description of Acetazolamide

Acetazolamide: The heterocyclic sulfonamide 5-acetylamido-1,3,4-thiadiazole-2-sulfonamide, which inhibits the action of carbonic anhydrase in the kidney, increasing the urinary excretion of sodium, potassium, and bicarbonate, reducing excretion of ammonium, raising the pH of the urine, and lowering the pH of the blood; used in respiratory acidosis for diuresis and to stimulate respiratory drive, in glaucoma to reduce intraocular pressure, and in epilepsy.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.

Acetazolamide: An agent that inhibits the function of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. Distributed throughout many cells and tissues, carbonic anhydrases play important roles in mineral and metabolic homeostasis. (NCI04)
Source: Diseases Database

Acetazolamide: carbonic anhydrase inhibitor that is sometimes effective against seizures.
Source: CRISP

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337).
Source: MeSH 2007

Drug name confusion

Because many drug names share similar spellings or sound almost identical when spoken, it is possible to mistake the name of a particular medication. Other drugs that are sometimes confused with Acetazolamide include:

• acetohexamide

Terms associated with Acetazolamide:

Broader terms for Acetazolamide

• Thiadiazoles

Source - MeSH 2007

• carbonic anhydrase inhibitor
• thiazole

Source - CRISP

Hierarchical classifications of Acetazolamide

The following list attempts to classify Acetazolamide into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Organic Chemicals
  • Sulfur Compounds
    • Thiazoles
      • Thiadiazoles
        • Acetazolamide

MeSH 2007 Hierarchy

• Heterocyclic Compounds
  • Heterocyclic Compounds, 1-Ring
    • Azoles
      • Thiazoles
        • Thiadiazoles
          • Acetazolamide

External links related to: Acetazolamide

• Carbonic anhydrase inhibitors for hypercapnic ventilatory failure in chronic obstructive pulmonary disease (Cochrane Review)
• Diamox Online, Description, Chemistry, Ingredients - Acetazolamide - RxList Monographs
• Acetazolamide (PIM 005)
• MedDet
• Diamox Online, Description, Chemistry, Ingredients - Acetazolamide - RxList Monographs

Source: Diseases Database

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