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Dictionary » Amifostine
 

Amifostine

Introduction: Amifostine

Description of Amifostine

Amifostine: A phosphorylated aminosulfhydryl compound. After dephosphorylation by alkaline phosphatase to an active free sulfhydryl (thiol) metabolite, amifostine binds to and detoxifies cytotoxic platinum-containing metabolites of cisplatin and scavenges free radicals induced by cisplatin and ionizing radiation. The elevated activity of this agent in normal tissues results from both the relative abundance of alkaline phosphatase in normal tissues and the greater vascularity of normal tissues compared to tumor tissues. (NCI04)
Source: Diseases Database

Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Source: MeSH 2007

Terms associated with Amifostine:

Terms Similar to Amifostine:

  • Ethiofos
  • Gammaphos

Source - MeSH 2007

Broader terms for Amifostine

Source - MeSH 2007

Hierarchical classifications of Amifostine

The following list attempts to classify Amifostine into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

MeSH 2007 Hierarchy

External links related to: Amifostine

Source: Diseases Database

Interesting Medical Articles:

Medical dictionaries:

More Medical Dictionary Topics

  • Catchment area
  • Catchment Area (Health)
  • CATCN2
  • CATCN21
  • Catechase
  • Catechin
  • Catechinic acid
  • Catechol
  • Catechol 1,2-dioxygenase
  • Catechol 2,3-dioxygenase

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