Busulfan

Introduction: Busulfan

Description of Busulfan

Busulfan: An anticancer drug that belongs to the family of drugs called alkylating agents.
Source: National Institute of Health

Busulfan: A synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription. (NCI04)
Source: Diseases Database

Busulfan: alkylating agent having a selective immunosuppressive effect on bone marrow; has been used in the palliative treatment of chronic myeloid leukemia.
Source: CRISP

Busulfan: An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Source: MeSH 2007

Drug name confusion

Because many drug names share similar spellings or sound almost identical when spoken, it is possible to mistake the name of a particular medication. Other drugs that are sometimes confused with Busulfan include:

• Butalan

Terms associated with Busulfan:

Terms Similar to Busulfan:

• Busulphan

Source: Diseases Database

• Busulphan

Source - MeSH 2007

Broader terms for Busulfan

• Butylene Glycols
• Mesylates

Source - MeSH 2007

• alkylating agent
• antineoplastic
• methane sulfonate

Source - CRISP

Hierarchical classifications of Busulfan

The following list attempts to classify Busulfan into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Organic Chemicals
  • Alcohols
    • Glycols
      • Butylene Glycols
        • Busulfan

MeSH 2007 Hierarchy

• Organic Chemicals
  • Hydrocarbons
    • Hydrocarbons, Acyclic
      • Alkanes
        • Alkanesulfonic Acids
          • Alkanesulfonates
            • Mesylates
              • Busulfan

MeSH 2007 Hierarchy

• Organic Chemicals
  • Sulfur Compounds
    • Sulfur Acids
      • Sulfonic Acids
        • Alkanesulfonic Acids
          • Alkanesulfonates
            • Mesylates
              • Busulfan

External links related to: Busulfan

• CancerSourceMD.Com Drug Guide
• Busilvex , SPC from the eMC
• RxMed: Pharmaceutical Information - MYLERAN
• Myleran film coated tablets 2mg , SPC from the eMC
• Myleran Online, Description, Chemistry, Ingredients - Busulfan - RxList Monographs
• MDAdvice.com - Health Library - Prescription & Non-Prescription Drugs - BUSULFAN

Source: Diseases Database

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• Medical dictionary,
• Medical Acronymns/Abbreviations

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