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Dictionary » Cholinesterase inhibitor

Cholinesterase inhibitor

Introduction: Cholinesterase inhibitor

Description of Cholinesterase inhibitor

Cholinesterase inhibitor: an agent or medication with effects that inhibit the enzyme responsible for the reuptake of acetylcholine at cholinergic synapses, thus perpetuating its action at the receptor; most notable therapeutic application is in the treatment of myasthenia gravis or after nondepolarizing neuromuscular relaxants have been administered.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.

Cholinesterase inhibitor: Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Source: Diseases Database

Cholinesterase inhibitor: any substance or agent which suppresses, prevents or opposes the action of cholinesterase resulting in the potentiation of the action of endogenously released acetylcholine at cholinergic synapses; cholinesterase inhibition is associated with a variety of acute symptoms such as nausea, vomiting, blurred vision, stomach cramps, and rapid heart rate.
Source: CRISP

Cholinesterase inhibitor: Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Source: MeSH 2007